Results 211 to 220 of about 710,958 (307)

A Radioresistant‐Tumor‐Targeted Nanoparticle for X‐Ray‐Controlled Nitric Oxide Release to Potentiate Radiotherapy

Advanced Science, EarlyView.
The PBTN targets GRP78 and, upon X‐ray irradiation, generates ONOO− to induce immunogenic cell death, thereby activating CD8+ T cells and establishing a systemic antitumor immune response. ABSTRACT Nitric oxide (NO) treated radioresistant tumors by relieving hypoxia and blocking DNA repair, but its nonselective toxicity has precluded therapeutic use ...
Wanze Zhang, Xiaoyan Yin, Ting Wang, Hongfu Zhao, Zhipeng Zhao, Jinbao Wang, Cheng Tao, Xuanchu Ge, Yanze Li, Linlin Liu, Fuxin Xue   +10 more
wiley   +1 more source

Predictive Value of Circulating Tumor Cells in Neoadjuvant Chemoimmunotherapy for Non-Small Cell Lung Cancer. [PDF]

Thorac Cancer
Yang J, Qin Z, Zhou Z, Liu J, Chen L, Mo Z, Liao M, Cui D, Wu K, Tang D, Chen J, Chen C.   +11 more
europepmc   +1 more source

The AUTACE That Degrades KRAS and Engages CD8+ T Cells for the Treatment of KRAS/TP53 Co‐Mutant Tumors

Advanced Science, EarlyView.
AUTACE is a bifunctional nanoplatform that integrates tumor targeting, immune engagement, and on‐demand KRAS degradation. It targets KRAS/TP53 co‐mutant tumors via TP53‐specific TCRs, elicits antitumor CD8+ T‐cell responses through surface anti‐CD3 antibodies, and uses low‐intensity focused ultrasound (LIFU) to trigger controlled release of the KRAS ...
Luo Li, Bolin Li, Yanan Hao, Bo Pang, Pan Li, Chunli Li, Yu Tang   +6 more
wiley   +1 more source

Can evolutionary therapy be applied in non-small cell lung cancer? [PDF]

Sci Rep
Jansén-Storbacka LR, Honasoge KS, Molnárová E, Soboleva A, Agema BC, Paats MS, Moes DJAR, Veerman GDM, Barbaro ABT, Dobbe R, Grossmann I, Azimi S, Mathijssen RHJ, Dingemans AC, Staňková K.   +14 more
europepmc   +1 more source

Autoimmune Encephalitis in Acute Care—Pathology, Diagnosis, and Management

Advanced Science, EarlyView.
ABSTRACT Autoimmune encephalitis (AE) is characterized by immune‐mediated inflammation of the brain parenchyma, presenting with various neurological syndromes, including but not limited to seizures, altered consciousness, neuropsychiatric symptoms, and movement disorders.
Suneesh Thilak, David Okoh, William Scotton, Shanika Samarasekera, Vikram Patil, Suresh Renukappa, Andrew Macduff, Subashini Suresh, Rajeev Krishnadas, Tonny Veenith   +9 more
wiley   +1 more source

[RNAi and non-small cell lung cancer.].

Zhongguo fei ai za zhi = Chinese journal of lung cancer, 2008
Chunyu YANG, Li CAI
openaire   +2 more sources

Updates in the Management of EGFR-Mutated Non-small Cell Lung Cancer (NSCLC). [PDF]

Curr Oncol Rep
Vyas A, Jeon WJ, Alhushki S, Singhi E, Rous FA, Thawani R, Desai A.   +6 more
europepmc   +1 more source

Activation of ERBB4 Pathway Inhibits Pathological Transdifferentiation of Lung Epithelial Progenitors into CD66c+ Basal Cells in Severe Lung Injury

Advanced Science, EarlyView.
In fibrotic distal lung regions, CD66c+ basal cells emerge as a pathological state. Using human distal lung organoids, this study identifies CD66c+ basal cells as a pro‐fibrotic state arising through transdifferentiation from secretory, AT2, and basal cells.
Kaijun Lin, Xinran Deng, Haonan Wang, Yamei Jiang, Jian Sun, Hailin Ding, Ming Ye, Xiaoting Wang, Yu Wang, Li Yuan, Zhenju Song, Xinhua Lin, Shenfei Sun, Ning Jiang   +13 more
wiley   +1 more source

Correction: Association of sarcopenia with survival and treatment response in brain metastasis of non-small cell lung cancer. [PDF]

Sci Rep
Schmidt L, Krenzlin H, Schmitz A, Jankovic D, Dauth A, Alessandri B, Sommer C, Brockmann MA, Ringel F, Keric N.   +9 more
europepmc   +1 more source