Non-specific effects of Pneumococcal and Haemophilus vaccines in children aged 5 years and under: a systematic review. [PDF]
Geraghty K +5 more
europepmc +1 more source
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Sex-Differential and Non-specific Effects of Vaccines Over the Life Course. [PDF]
St Clair LA +4 more
europepmc +1 more source
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Reactive oxygen species production during non-specific elicitation, non-host resistance and field resistance expression in cultured tobacco cells. [PDF]
[Abstract]: We examined production of reactive oxygen species (ROS) and induction of cell death in tissue-cultured tobacco cells undergoing different disease resistance responses. A superoxide-dependent hypersensitive response occurs during both the race-
Sutherland, Mark W. +2 more
core
A flow diagram of Chiari I Malformation compression injury and non-specific effects is presented.
Under “What,” the anatomical areas or types of non-specific effects are presented. Under “How,” the type of injury or state-dependent effect is presented.
A. Katherine Harrington (552419) +10 more
core +1 more source
Correction to: Sex-Differential and Non-specific Effects of Vaccines Over the Life Course. [PDF]
St Clair LA +4 more
europepmc +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Nanomedicinal products: a survey on specific toxicity and side effects
Walter Brand,1,* Cornelle W Noorlander,1,* Christina Giannakou,2,3 Wim H De Jong,2 Myrna W Kooi,1 Margriet VDZ Park,2 Rob J Vandebriel,2 Irene EM Bosselaers,4 Joep HG Scholl,5 Robert E Geertsma2 1Centre for Safety of Substances and Products, 2Centre for
Brand W +9 more
core
The review of the Terrestrial Ecotoxicology Guidance concerns three groups of non‐target organisms (NTOs): non‐target arthropods other than bees, in‐soil organisms and non‐target terrestrial plants. Thus, specific protection goals (SPGs) would need to be
European Food Safety Authority (EFSA) +16 more
doaj +1 more source

