The Yin and Yang of the Non-Specific Effects of Vaccines [PDF]
EBioMedicine, 2017 Stephen Cose
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Non-specific Effects of Vaccines and Stunting: Timing May Be Essential [PDF]
EBioMedicine, 2016 Background: Bacillus Calmette-Guérin (BCG) vaccination possesses effects on health beyond its target disease, the so called “non-specific effects”. We evaluate these effects, as well as the effect of timing of BCG and other vaccinations, on stunting in ...
Mike L.T. Berendsen +3 more
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Non-specific Effects of Vaccines Illustrated Through the BCG Example: From Observations to Demonstrations [PDF]
Frontiers in Immunology, 2018 Epidemiological studies regarding many successful vaccines suggest that vaccination may lead to a reduction in child mortality and morbidity worldwide, on a grander scale than is attributable to protection against the specific target diseases of these ...
Deeva Uthayakumar +9 more
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Sex-Differential and Non-specific Effects of Vaccines Over the Life Course. [PDF]
Curr Top Microbiol Immunol, 2023 Biological sex and age have profound effects on immune responses throughout the lifespan and impact vaccine acceptance, responses, and outcomes. Mounting evidence from epidemiological, clinical, and animal model studies show that males and females respond differentially to vaccination throughout the lifespan.
St Clair LA +4 more
europepmc +4 more sources
Harnessing the non-specific immunogenic effects of available vaccines to combat COVID-19 [PDF]
Human Vaccines & Immunotherapeutics, 2021 No proven remedy is identified for COVID-19 yet. SARS-CoV-2, the viral agent, is recognized by some endosomal and cytosolic receptors following cell entry, entailing innate and adaptive immunity stimulation, notably through interferon induction ...
Pouria Mosaddeghi +4 more
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Systematic review and meta-analysis of the non-specific and broader impact of respiratory vaccines on acute lower respiratory infections in young children [PDF]
BMJ OpenObjectives Growing evidence suggests that vaccines targeting respiratory pathogens have non-specific and broader effects. We aimed to investigate the non-specific effects of respiratory vaccines on acute lower respiratory infection (ALRI ...
Leo Ng +5 more
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Australia, immunisation, GAVI, and the non‐specific effects of vaccines [PDF]
Australian and New Zealand Journal of Public Health, 2012 Frank Shann
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Non-specific effects of vaccination [PDF]
BMJ, 2005 EDITOR—Shann rightly questions the subtitle to my editorial, “Literature does not support either beneficial or detrimental effects.” I did not write it and failed to note its insertion by the editor at the last moment before the article went to press—for which I apologise. Of course, there are many well documented non-specific …
J Vaugelade +4 more
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EClinicalMedicine, 2021 Background: West African studies have suggested that national immunisation campaigns with oral polio vaccine (C-OPV) may non-specifically reduce all-cause child mortality rate by 15–25%.
Sebastian Nielsen +4 more
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Oral Polio Vaccine Campaigns May Reduce the Risk of Death from Respiratory Infections
Vaccines, 2021 Oral polio vaccine (OPV) campaigns, but not other campaigns, have been associated with major reductions in child mortality. Studies have shown that OPV reduces the risk of respiratory infections.
Sebastian Nielsen +4 more
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