Results 11 to 20 of about 202,719 (283)

Randomized clinical trials of COVID-19 vaccines: Do adenovirus-vector vaccines have beneficial non-specific effects? [PDF]

open access: yesiScience, 2023
Summary: We examined the possible non-specific effects of novel mRNA- and adenovirus-vector COVID-19 vaccines by reviewing the randomized control trials (RCTs) of mRNA and adenovirus-vector COVID-19 vaccines. We calculated mortality risk ratios (RRs) for
Christine S. Benn   +4 more
doaj   +3 more sources

Implications of Non-Specific Effects for Testing, Approving, and Regulating Vaccines [PDF]

open access: yesDrug Safety, 2023
The current framework for testing and regulating vaccines was established before the realization that vaccines, in addition to their effect against the vaccine-specific disease, may also have "non-specific effects" affecting the risk of unrelated diseases.
Christine Stabell Benn   +15 more
core   +10 more sources

Non-specific effects of veterinary vaccines: a systematic review [PDF]

open access: yesVaccine, 2022
The benefits of vaccines have been centred on their specific effects on subsequent infections by target pathogens. Recent studies, however, have opened up new insights into additional effects of vaccines known as non-specific effects (NSEs) or heterologous effects of vaccines.
Arega, Sintayehu   +3 more
openaire   +4 more sources

Do childhood vaccines have non-specific effects on mortality? [PDF]

open access: yesBulletin of the World Health Organization, 2003
A recent article by Kristensen et al. suggested that measles vaccine and bacille Calmette-Gu rin (BCG) vaccine might reduce mortality beyond what is expected simply from protection against measles and tuberculosis. Previous reviews of the potential effects of childhood vaccines on mortality have not considered methodological features of reviewed ...
Cooper, O. William   +3 more
core   +6 more sources

Australia, immunisation, GAVI, and the non‐specific effects of vaccines [PDF]

open access: yesAustralian and New Zealand Journal of Public Health, 2012
Frank Shann
doaj   +3 more sources

How to evaluate potential non-specific effects of vaccines: the quest for randomized trials or time for triangulation?

open access: yesExpert Review of Vaccines, 2018
Introduction: Emerging evidence suggests that vaccines, in addition to their disease-specific effects, have important non-specific effects (NSEs), which contribute to their overall effect on mortality and morbidity.
Christine Stabell Benn   +4 more
doaj   +2 more sources

Non-specific effects of vaccination [PDF]

open access: yesBMJ, 2005
EDITOR—Shann rightly questions the subtitle to my editorial, “Literature does not support either beneficial or detrimental effects.” I did not write it and failed to note its insertion by the editor at the last moment before the article went to press—for which I apologise. Of course, there are many well documented non-specific …
J Vaugelade   +4 more
  +9 more sources

National immunisation campaigns with oral polio vaccine may reduce all-cause mortality: Analysis of 2004–2019 demographic surveillance data in rural Bangladesh

open access: yesEClinicalMedicine, 2021
Background: West African studies have suggested that national immunisation campaigns with oral polio vaccine (C-OPV) may non-specifically reduce all-cause child mortality rate by 15–25%.
Sebastian Nielsen   +4 more
doaj   +1 more source

Oral Polio Vaccine Campaigns May Reduce the Risk of Death from Respiratory Infections

open access: yesVaccines, 2021
Oral polio vaccine (OPV) campaigns, but not other campaigns, have been associated with major reductions in child mortality. Studies have shown that OPV reduces the risk of respiratory infections.
Sebastian Nielsen   +4 more
doaj   +1 more source

Health effects of utilising hospital contacts to provide measles vaccination to children 9–59 months—a randomised controlled trial in Guinea-Bissau

open access: yesTrials, 2022
Background Measles vaccination coverage in Guinea-Bissau is low; fewer than 80% of children are currently measles vaccinated before 12 months of age. The low coverage hampers control of measles.
Ane B. Fisker   +5 more
doaj   +1 more source

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