Results 41 to 50 of about 205,611 (276)

Prospects on Repurposing a Live Attenuated Vaccine for the Control of Unrelated Infections

Frontiers in Immunology, 2022
Live vaccines use attenuated microbes to acquire immunity against pathogens in a safe way. As live attenuated vaccines (LAVs) still maintain infectivity, the vaccination stimulates diverse immune responses by mimicking natural infection.
Sang-Uk Seo, Baik-Lin Seong, Baik-Lin Seong   +2 more
doaj   +1 more source

National Immunization Campaigns with Oral Polio Vaccine Reduce All-Cause Mortality: A Natural Experiment within Seven Randomized Trials

Frontiers in Public Health, 2018
BackgroundA recent WHO review concluded that live BCG and measles vaccine (MV) may have beneficial non-specific effects (NSEs) reducing mortality from non-targeted diseases. NSEs of oral polio vaccine (OPV) were not examined. If OPV vaccination campaigns
Andreas Andersen, Ane Baerent Fisker, Amabelia Rodrigues, Cesario Martins, Henrik Ravn, Henrik Ravn, Najaaraq Lund, Sofie Biering-Sørensen, Christine Stabell Benn, Christine Stabell Benn, Peter Aaby, Peter Aaby, Peter Aaby   +12 more
doaj   +1 more source

Measles Vaccination in Presence of Measles Antibody May Enhance Child Survival

Frontiers in Pediatrics, 2020
Background: In trials of early two-dose measles vaccination (MV), with the first dose being given before 9 months of age, vaccination in the presence of maternal antibody reduced mortality 2- to 3-fold compared with MV in the presence of no measles ...
Christine S. Benn, Christine S. Benn, Christine S. Benn, Cesário L. Martins, Andreas Andersen, Andreas Andersen, Ane B. Fisker, Ane B. Fisker, Ane B. Fisker, Hilton C. Whittle, Peter Aaby, Peter Aaby   +11 more
doaj   +1 more source

Non‐specific effects of vaccination on child survival? A prospective study in Senegal [PDF]

Tropical Medicine & International Health, 2005
SummaryObjectives  Several studies have shown an association between vaccination and child mortality in developing countries. The present paper examines this issue using data from a Senegalese rural area which has been monitored from 1983 to the present.Methods  We analysed two birth cohorts, comprising 7796 and 3573 persons who had received either BCG
Elguero, Eric, Simondon, Kirsten, Vaugelade, Jacques, Marra, Adama, Simondon, François   +4 more
openaire   +3 more sources

The non‐specific effects of maternal immunization on birth outcomes: The evidence, mechanisms, and the implications

International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2023
Preterm birth (PTB) and stillbirth remain two of the most important causes of death, morbidity, and disability in childhood. Despite efforts to reduce PTB and stillbirth worldwide, rates of these adverse outcomes remain persistently elevated, independent
M. Giles, Ahinsa Gunatilaka, S. Cole, T. Kollmann   +3 more
semanticscholar   +1 more source

Implications of the non-specific effect induced by Bacillus Calmette-Guerin (BCG) vaccine on vaccine recommendations

Jornal de Pediatria, 2023
Since the beginning of its use for the prevention of tuberculosis (TB) in 1921, other uses of BCG (Bacillus Calmette-Guérin) have been proposed, particularly in the treatment of malignant solid tumors, multiple sclerosis, and other autoimmune diseases.
Ekaterini Goudouris, Carolina Sanchez Aranda, Dirceu Solé   +2 more
openaire   +4 more sources

Non-Specific Effects of Bacillus Calmette-Guérin: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

medRxiv, 2022
Vaccines induce antigen-specific immunity which provides long-lived protection from the target pathogen. Trials especially from high infectious disease areas indicated that the tuberculosis vaccine Bacillus Calmette-Guerin (BCG) induces in addition non ...
G. Trunk, M. Davidović, J. Bohlius
semanticscholar   +1 more source

Non-specific effects of rabies vaccine on the incidence of common infectious disease episodes: study protocol for a randomized controlled trial

Trials, 2020
Background Vaccines may cause non-specific effects (NSEs) on morbidity and mortality through immune-mediated mechanisms that are not explained by the prevention of the targeted disease.
Darryn Knobel, Christianah Ibironke Odita, Anne Conan, Donna Barry, Marshalette Smith-Anthony, Juliet Battice, Shianne England, Bradford D. Gessner   +7 more
doaj   +1 more source

Potential role of specific antibodies as important vaccine induced protective mechanism against Aeromonas salmonicida in rainbow trout. [PDF]

PLoS ONE, 2012
Furunculosis caused by infection with Aeromonas salmonicida subsp. salmonicida has been a known threat to aquaculture for more than a century. Efficient prophylactic approaches against this disease are essential for continued growth of salmonid ...
Kasper Rømer Villumsen, Inger Dalsgaard, Lars Holten-Andersen, Martin Kristian Raida   +3 more
doaj   +1 more source

Non-specific effects of Pneumococcal and Haemophilus vaccines in children aged 5 years and under: a systematic review

BMJ Open, 2023
Objective To determine the evidence for non-specific effects of the Pneumococcal and Haemophilus influenza vaccine in children aged 5 years and under.Data sources A key word literature search of MEDLINE, EMBASE, The Cochrane Central Register of ...
Liam Glynn, Chris Watson, Joe Gallagher, Keith Geraghty, Mark T Ledwidge, Darragh Rooney   +5 more
doaj   +1 more source