Results 61 to 70 of about 202,719 (283)

The Introduction of Diphtheria-Tetanus-Pertussis and Oral Polio Vaccine Among Young Infants in an Urban African Community: A Natural Experiment

EBioMedicine, 2017
Background: We examined the introduction of diphtheria-tetanus-pertussis (DTP) and oral polio vaccine (OPV) in an urban community in Guinea-Bissau in the early 1980s.
Søren Wengel Mogensen, Andreas Andersen, Amabelia Rodrigues, Christine S Benn, Peter Aaby   +4 more
doaj   +1 more source

Complete and on-time routine childhood immunisation: determinants and association with severe morbidity in urban informal settlements, Nairobi, Kenya

Annals of Human Biology, 2020
Background: Completion of the full series of childhood vaccines on-time is crucial to ensuring greater protection against vaccine-preventable diseases. Aim: To examine determinants of complete and on-time vaccination and evaluate the relationship between
Martin K. Mutua, Shukri F. Mohamed, Elizabeth W. Kimani-Murage, Lucy Kiarie, Cara Bess Janusz, Peter Aaby, Ane B. Fisker, Elizabeth Echoka, Henrik Ravn   +8 more
doaj   +1 more source

Evaluation of non-specific effects of human rotavirus vaccination in medical risk infants

Vaccine, 2021
The WHO recommends research into non-specific effects of vaccination. For rotavirus vaccines, these have not yet been well established. We studied non-specific effects up to 18 months of age using data from a quasi-experimental before-after study comparing cohorts of rotavirus vaccinated and unvaccinated infants with medical risk conditions.Infants ...
Josephine A P, van Dongen, Elsbeth D M, Rouers, Marc J M, Bonten, Patricia C J, Bruijning-Verhagen   +3 more
openaire   +2 more sources

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

FEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

A Prospective Study of Individuals at Risk of Multiple Sclerosis Informs the Design of Primary Prevention Studies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective In multiple sclerosis, the optimal time for deploying a therapeutic intervention is before the central nervous system is damaged; given the success of trials treating the earliest stage of MS, the radiologically isolated syndrome, developing primary prevention strategies is an important next challenge.
Amy W. Laitinen, Ceren Tozlu, Tina Roostaei, Fatoumata Diallo, Kaho Onomichi, Jiyeon Son, Zongqi Xia, Philip L. De Jager   +7 more
wiley   +1 more source

Contradictory mortality results in early 2-dose measles vaccine trials: interactions with oral polio vaccine may explain differences

International Journal of Infectious Diseases
Objectives: Between 2003 and 2019, three trials (randomised controlled trials [RCTs]) in Guinea-Bissau randomised infants to an early 2-dose measles vaccine (MV) schedule at 4 and 9 months vs standard MV at 9 months.
Sebastian Nielsen, Ane B. Fisker, Ali Sie, Olaf Müller, Eric Nebie, Heiko Becher, Fiona van der Klis, Sofie Biering-Sørensen, Stine Byberg, Sanne M. Thysen, Isaquel da Silva, Amabelia Rodrigues, Cesario Martins, Hilton C. Whittle, Peter Aaby, Christine S. Benn   +15 more
doaj   +1 more source

Immunostimulation with oral vaccines for prevention and treatment of respiratory tract infections

Pediatria i Medycyna Rodzinna, 2016
The respiratory system is susceptible to unfavourable effects of biological and non-biological factors. In the protection against infectious agents, the immune system plays a crucial role thanks to close cooperation of specific (acquired) and non ...
Robert Szamborski
doaj   +1 more source

Influenza Vaccination Responses in Disabled Stroke Patients: A Single‐Center Prospective Observational Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to investigate the immunological response to influenza vaccination, the incidence and severity of influenza infection, and the side effects of the vaccination in patients with ischemic stroke. Methods This prospective observational study was conducted between 2023 and 2024 at Ramathibodi Hospital.
Achiraya Pakngao, Sureerat Suwatcharangoon, Pintip Ngamjanyapron, Kobporn Boonnak, Thanitta Suangtamai, Porpon Rotjanapan   +5 more
wiley   +1 more source

The Effect of Inactivated Mycobacterium Paratuberculosis Vaccine on the Response to a Heterologous Bacterial Challenge in Pigs

Frontiers in Immunology, 2019
Background: Vaccines may have non-specific effects, affecting resistance to heterologous pathogens. Veterinary vaccines have seldom been investigated for their non-specific effects.
Kristoffer Jarlov Jensen, Kristoffer Jarlov Jensen, Mette Sif Hansen, Peter Mikael Helweg Heegaard, Christine Stabell Benn, Christine Stabell Benn, Gregers Jungersen   +6 more
doaj   +1 more source

Recent Advances in Cancer Vaccines: Challenges, Achievements, and Futuristic Prospects

Vaccines, 2022
Cancer is a chronic disease, and it can be lethal due to limited therapeutic options. The conventional treatment options for cancer have numerous challenges, such as a low blood circulation time as well as poor solubility of anticancer drugs. Therapeutic
Madhu Gupta, Abhishek Wahi, Priyanka Sharma, Riya Nagpal, Neha Raina, Monika Kaurav, Jaydeep Bhattacharya, Sonia M. Rodrigues Oliveira, Karma G. Dolma, Alok K. Paul, Maria de Lourdes Pereira, Polrat Wilairatana, Mohammed Rahmatullah, Veeranoot Nissapatorn   +13 more
doaj   +1 more source