Results 81 to 90 of about 346,212 (321)

Immunostimulation with oral vaccines for prevention and treatment of respiratory tract infections

Pediatria i Medycyna Rodzinna, 2016
The respiratory system is susceptible to unfavourable effects of biological and non-biological factors. In the protection against infectious agents, the immune system plays a crucial role thanks to close cooperation of specific (acquired) and non ...
Robert Szamborski
doaj   +1 more source

Complete and on-time routine childhood immunisation: determinants and association with severe morbidity in urban informal settlements, Nairobi, Kenya

Annals of Human Biology, 2020
Background: Completion of the full series of childhood vaccines on-time is crucial to ensuring greater protection against vaccine-preventable diseases. Aim: To examine determinants of complete and on-time vaccination and evaluate the relationship between
Martin K. Mutua, Shukri F. Mohamed, Elizabeth W. Kimani-Murage, Lucy Kiarie, Cara Bess Janusz, Peter Aaby, Ane B. Fisker, Elizabeth Echoka, Henrik Ravn   +8 more
doaj   +1 more source

Recent Advances in Cancer Vaccines: Challenges, Achievements, and Futuristic Prospects

Vaccines, 2022
Cancer is a chronic disease, and it can be lethal due to limited therapeutic options. The conventional treatment options for cancer have numerous challenges, such as a low blood circulation time as well as poor solubility of anticancer drugs. Therapeutic
Madhu Gupta, Abhishek Wahi, Priyanka Sharma, Riya Nagpal, Neha Raina, Monika Kaurav, Jaydeep Bhattacharya, Sonia M. Rodrigues Oliveira, Karma G. Dolma, Alok K. Paul, Maria de Lourdes Pereira, Polrat Wilairatana, Mohammed Rahmatullah, Veeranoot Nissapatorn   +13 more
doaj   +1 more source

A prime/boost DNA/Modified vaccinia virus Ankara vaccine expressing recombinant Leishmania DNA encoding TRYP is safe and immunogenic in outbred dogs, the reservoir of zoonotic visceral leishmaniasis [PDF]

Previous studies demonstrated safety, immunogenicity and efficacy of DNA/modified vaccinia virus Ankara (MVA) prime/boost vaccines expressing tryparedoxin peroxidase (TRYP) and Leishmania homologue of the mammalian receptor for activated C kinase (LACK ...
Alcami, Antonio, Antoniou, Maria, Begoña Ruiz-Argüello, Maria, Blackwell, Jenefer M., Carson, Connor, Christodoulou, Vasiliki, Courtenay, Orin, Messaritakis, Ippokratis   +7 more
core   +1 more source

Biological therapy in the treatment of melanoma [PDF]

, 2018
Melanoma is one of the most aggressive tumors and its incidence is on the rise. The low rates of survival in metastatic melanoma has led to the development of new drugs for this type of patient, such as biological therapy which has shown remarkable ...
Benea, Vasile, Georgescu, Simona Roxana, Ghita, Ela, Ioghen, Mihaela Roxana, Ion, Alexandra-Florentina, Mitran, Cristina-Iulia, Mitran, Madalina-Irina, Sarbu, Maria Isabela, Tampa, Mircea   +8 more
core   +3 more sources

Portable Low‐Field Magnetic Resonance Imaging in People With Human Immunodeficiency Virus

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The aging population of people with HIV (PWH) raises heightened concerns regarding accelerated aging and dementia. Portable, low‐field MRI (LF‐MRI) is an innovative technology that could enhance access and facilitate routine monitoring of PWH.
Annabel Sorby‐Adams, Malachi Keo, Jennifer Guo, Daire Daly, Richard Ahern, Kimon Zachary, Gregory Robbins, Rajesh T. Gandhi, Bragi Sveinsson, Adam de Havenon, Kevin N. Sheth, Otto Rapalino, Juan Eugenio Iglesias Gonzales, W. Taylor Kimberly, Shibani S. Mukerji   +14 more
wiley   +1 more source

Contradictory mortality results in early 2-dose measles vaccine trials: interactions with oral polio vaccine may explain differences

International Journal of Infectious Diseases
Objectives: Between 2003 and 2019, three trials (randomised controlled trials [RCTs]) in Guinea-Bissau randomised infants to an early 2-dose measles vaccine (MV) schedule at 4 and 9 months vs standard MV at 9 months.
Sebastian Nielsen, Ane B. Fisker, Ali Sie, Olaf Müller, Eric Nebie, Heiko Becher, Fiona van der Klis, Sofie Biering-Sørensen, Stine Byberg, Sanne M. Thysen, Isaquel da Silva, Amabelia Rodrigues, Cesario Martins, Hilton C. Whittle, Peter Aaby, Christine S. Benn   +15 more
doaj   +1 more source

Heterologous Immunity: Role in Natural and Vaccine-Induced Resistance to Infections

Frontiers in Immunology, 2019
The central paradigm of vaccination is to generate resistance to infection by a specific pathogen when the vacinee is re-exposed to that pathogen. This paradigm is based on two fundamental characteristics of the adaptive immune system, specificity and ...
Babita Agrawal
doaj   +1 more source

Mucosal delivery of tuberculosis vaccines: a review of current approaches and challenges. [PDF]

, 2019
Introduction: Tuberculosis (TB) remains a major health threat and it is now clear that the current vaccine, BCG, is unable to arrest the global TB epidemic. A new vaccine is needed to either replace or boost BCG so that a better level of protection could
Barclay WR, Elena Stylianou, Helen McShane, Matthew J. Paul, Rajko Reljic, Resende Co T, Rodriguez A, Uranga S, Wong EA   +8 more
core   +1 more source

Developing the concept of beneficial non-specific effect of live vaccines with epidemiological studies [PDF]

Clinical Microbiology and Infection, 2019
Epidemiological and immunological studies are increasingly reporting non-specific effects (NSEs) of vaccines; i.e. vaccines may affect the risk and severity of non-targeted infections. We reviewed how epidemiological studies developed the concept of beneficial NSEs of live vaccines.This is a personal narrative of how we came to pursue the concept of ...
Aaby, P., Benn, C. S.
openaire   +4 more sources