Results 51 to 60 of about 481,480 (297)
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Non-State Actors in Asymmetric Conflicts: What does It Mean and What Follows of It
Международная аналитикаThe article examines the problem of the participation of non-state actors in armed conflicts in the post-war period. The study is based on the theory of asymmetric conflict, which offers hypotheses about the reasons for the paradoxical defeat of ...
L. V. Deriglazova
doaj +1 more source
Section XVIII: Extraterritorial Operations Against Non-state Armed Groups [PDF]
, 2020 AbstractThe right of self-defence applies in response to an armed attack by non-State armed groups.
Yoram Dinstein, Arne Willy Dahl
openaire +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Ideology and civilian victimization in civil war [PDF]
, 2017 Why do some groups fighting in civil wars target civilians more than others? We propose an explanation that challenges the current focus on material and organizational factors and instead brings back and emphasizes the role of ideology. We argue that the
Ahmadov, Anar, Hughes, James
core
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
International legal obligations of armed opposition groups in Syria
International Review of Law, 2015 Starting with peaceful protests of people demanding democratic reforms and fundamental rights from the regime in Damascus, the Syria crisis developed into a full-fledged civil war causing largescale death, injury, and displacement.
Tilman Rodenhäuser
doaj +2 more sources
„The Good, the Bad and the Ugly”: Terrorists and NGOs in Modern Armed Conflicts
Facta Simonidis, 2019 The article aims at analyzing the roles played by the so-called non-state actors (NSAs) in modern armed conflicts. The analysis covered the activities of two classes of entities, i.e.
Michał Wallner
doaj +1 more source
War Everywhere: Rights, National Security Law, and the Law of Armed Conflict in the Age of Terror [PDF]
, 2004 Both international and domestic law take as a basic premise the notion that it is possible, important, and usually fairly straightforward to distinguish between war and peace, emergencies and normality, the foreign and the domestic, the external and the ...
Brooks, Rosa Ehrenreich
core +2 more sources
‘New’ and ‘old’ wars – the changing dimensions of warfare [PDF]
, 2018 The article aims to present the issue of ‘old’ versus ‘new’ wars in relation to their specific features. It focuses on the characteristics of both phenomena, as well as providing an analysis of the causes and sources of armed conflicts and their changing
Antczak, Anna
core +3 more sources