Results 111 to 120 of about 10,498,931 (287)

Self‐Sealing Microneedles Improve Precision and Reduce Reflux in Subretinal Cell Transplantation

open access: yesAdvanced Materials Technologies, EarlyView.
Ultrafine 49G microneedles enable subretinal delivery of induced pluripotent stem cell‐derived retinal pigment epithelial cells through a 50 µm outer diameter tip. Compared with conventional 38G microcannulas, these microneedles reduce cell suspension reflux in a rabbit model, highlighting the potential of microinvasive delivery instruments to improve ...
Jared Ching   +9 more
wiley   +1 more source

Risk Factors of Nonsteroidal Anti-inflammatory Drug-exacerbated Respiratory Disease: A Systematic Review and Meta-analysis of Observational Studies

open access: yesOman Medical Journal
Objectives: This meta-analysis aimed to identify the risk factors associated with nonsteroidal anti-inflammatory drug -exacerbated respiratory disease (NERD), a chronic eosinophilic, inflammatory respiratory disorder characterized by hypersensitivity to ...
Edwin Nugroho Njoto   +8 more
doaj   +1 more source

Inflammation Unchecked: Concurrent Kawasaki Disease and Stevens‐Johnson Syndrome in an 18‐Month‐Old Child

open access: yes
Arthritis Care &Research, EarlyView.
Catherine Deffendall   +6 more
wiley   +1 more source

An Anti‐Amyloidogenic Approach to Specifically Block Memory Consolidation in Mice for Therapeutic Intervention

open access: yesAdvanced Science, EarlyView.
Functional amyloid conversion of the translation regulator CPEB3 is essential for long‐term memory persistence. This study demonstrates that targeting this molecular switch with the anti‐amyloidogenic peptide QBP1 selectively blocks CPEB3 fibrillation without disrupting phase separation.
Paula López‐García   +13 more
wiley   +1 more source

Modes of cell death induced by tetrahydroisoquinoline-based analogs in MDA-MB-231 breast and A549 lung cancer cell lines

open access: yesDrug Design, Development and Therapy, 2018
Marcel Nel,1 Anna M Joubert,1 Wolfgang Dohle,2 Barry VL Potter,2 Anne E Theron1 1Department of Physiology, Faculty of Health Sciences, University of Pretoria, Pretoria, South Africa; 2Medicinal Chemistry & Drug Discovery, Department of Pharmacology,
Nel M   +4 more
doaj  

Effect of nonsteroidal anti-inflammatory drug Rofecoxib (Vioxx™) on the bone repair [PDF]

open access: yesRGO: Revista Gaúcha de Odontologia, 2008
Objective: To evaluate the effect of the nonsteroidal anti-inflammatory drug Rofecoxib (Vioxx™) on the bone repair process in the tibiae of stressed rats.
Luiz Alberto Milanezi   +2 more
doaj  

List of Non Steroidal Anti-inflammatory Drugs (NSAIDs) included in the study grouped by pharmacological class.

open access: yes, 2015
List of Non Steroidal Anti-inflammatory Drugs (NSAIDs) included in the study grouped by pharmacological class.
Stefan Visscher (140386)   +5 more
core   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

open access: yesAdvanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang   +6 more
wiley   +1 more source

Making Sweat Measurable: Induction, Sampling, and Refreshment in Wearable Biofluid Sensing

open access: yesAdvanced Science, EarlyView.
Wearable sweat sensing relies not only on chemical detection but also on controlled biofluid management. This Review integrates sweat physiology, induction strategies, and microfluidic sampling architectures, demonstrating how flux, transport, and refreshment shape measurement reliability.
Soyoung Shin, Wei Gao
wiley   +1 more source

Transcription Factor HOXC11 Drives Colorectal Cancer Progression and Metastasis via CAMK2A‐Dependent CXCL5 Upregulation

open access: yesAdvanced Science, EarlyView.
HOXC11 drives colorectal cancer progression by transcriptionally activating CAMK2A, which triggers NF‐κB–dependent CXCL5 upregulation. CXCL5–CXCR2 signaling further reinforces HOXC11 expression through the ERK1/2–SP1 axis, forming a prometastatic positive feedback loop that is effectively disrupted by combined CAMK2A and CXCR2 inhibition.
Qingyang Sun   +12 more
wiley   +1 more source

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