Results 151 to 160 of about 225,445 (370)

Germanane Quantum Dots Promote Metabolic Reprogramming of Immune Cells Toward Regulatory T Cells and Suppress Inflammation In Vitro and In Vivo

Advanced Functional Materials, EarlyView.
Metabolic changes in immune cells direct the phenotype and function of the host immune system. Smart nanomaterials must target metabolic pathways to direct immune cell fate. This study reports the fabrication and first application of germanane quantum dots (GeHQDs) to modulate inflammation in vitro and in vivo.
Abhay Srivastava, Alireza Rafieerad, Weiang Yan, Keshav Narayan Alagarsamy, Qingdong Guan, Leena Regi Saleth, Michel Aliani, Sanjiv Dhingra   +7 more
wiley   +1 more source

Generation of an Induced Pluripotent Stem Cell‐Derived Alveolar Type II In Vitro Model to Study Influenza A Virus Infection and Drug Treatments

Advanced Healthcare Materials, EarlyView.
Patient‐specific induced pluripotent stem cells (iPSCs) can be differentiated into alveolar type II cells (iAT2s), expanded as 3D alveolospheres, and grown at physiologically relevant air–liquid interface (ALI). This study shows for the first time the infectability of iAT2s by the influenza A virus (IAV) and proves their responsiveness to the well ...
Lena Gauthier, Hristina Koceva, Yann Bachelot, Rosanne W. Koutstaal, Puck B. van Kasteren, Marc Thilo Figge, Christian Eggeling, Alexander Sandy Mosig   +7 more
wiley   +1 more source

Effects of Steroidal and Non Steroidal Drugs on the Neovascularization Response Induced by Tumoral TA3 Supernatant on CAM from Chick Embryo

Biological Research, 2003
Angiogenesis, the development of new blood vessels from the existing vascular network, may result as a consequence of the increase or decrease of proangiogenic or antiangiogenic factors, respectively.
JORGE ZÚÑIGA, MARCELA FUENZALIDA, ANÍBAL GUERRERO, JULIO ILLANES, ALFREDO DABANCENS, EUGENIA DÍAZ, DAVID LEMUS   +6 more
doaj  

DOCKING STUDIES OF THE MECHANISM OF ACTION OF A POTENTIAL NON-STEROIDAL ANTI-INFLAMMATORY AGENT 3-[(3,5-DICHLOROPYRIDIN-2-YL)OXY]- 3,4-DIHYDRO-2H-BENZO[4,5]-IMIDAZO[2,1-B][1,3]-THIAZINE

, 2022
Nataliia SLYVKA, Lesya Saliyeva, Serhii HOLOTA, Vasyl Zhylko, Dmytro KHYLUK, M. V. Vovk   +5 more
openalex   +2 more sources

Sulindac sulfide reverses aberrant self-renewal of progenitor cells induced by the AML-associated fusion proteins PML/RARalpha and PLZF/RARalpha [PDF]

, 2011
Chromosomal translocations can lead to the formation of chimeric genes encoding fusion proteins such as PML/RARalpha, PLZF/RARalpha, and AML-1/ETO, which are able to induce and maintain acute myeloid leukemia (AML). One key mechanism in leukemogenesis is
Hagemeyer, Heike, Maier, Thorsten Jürgen, Oancea, Claudia, Puccetti, Elena, Roos, Jessica, Ruthardt, Martin, Steinert, Gunnar   +6 more
core  

Ascorbic Acid Modulates Collagen Properties in Glucocorticoid‐Induced Osteoporotic Bone: Insights into Chemical, Mechanical, and Biological Regulation

Advanced Healthcare Materials, EarlyView.
Osteoporosis from long‐term glucocorticoid (GIOP) use elevates susceptibility to fracture. This study shows GCs impair ascorbic acid (AA) metabolism in osteoblasts, collagen synthesis and extracellular matrix integrity. AA enhanced collagen biochemical and mechanical properties and restored osteoblast and endothelial function. These findings underscore
Micaila DE Curtis, Yoontae Kim, Rahul Patil, Xinran Zhang, Meth Jayatilake, Orelle Bulgin, Peter Lialios, Sana Surrency, Soraya Tarrah, Argyris K. Lazaris, Alison Grafton, James Williams IV, Seyedeh Boshra Nouraie, Maria Bizaki, Penelope Xeron, Edward Van Keuren, Jonathan E. Seppala, Evagelia C. Laiakis, Joanna B. Kitlinska, Stella Alimperti   +19 more
wiley   +1 more source

Acute gastrointestinal permeability responses to different non-steroidal anti-inflammatory drugs [PDF]

, 2001
Edgardo Smecuol, J C Bai, E Sugai, H Vazquez, S Niveloni, S Pedreira, E Mauriño, J Meddings   +7 more
openalex   +1 more source

Use of non-steroidal anti-inflammatory drugs and adverse outcomes during the COVID-19 pandemic: A systematic review and meta-analysis [PDF]

, 2022
Qi Zhou, Siya Zhao, Lidan Gan, Zhili Wang, Shuai Peng, Qinyuan Li, Hui Liu, Xiao Liu, Zijun Wang, Qianling Shi, Janne Estill, Zhengxiu Luo, Xiaohui Wang, Enmei Liu, Yaolong Chen   +14 more
openalex   +1 more source

Clinical Use of S53P4 Bioactive Glass in the Treatment of Bone Defects and Infected Bone: A Systematic Review of the Quality of Clinical Outcomes and A Grade Assessment

Advanced Healthcare Materials, EarlyView.
Bioactive glass (BAG) S53P4 is a synthetic bone substitute. Clinically it has been used in the treatment of benign bone tumor surgery, in spine surgery, in trauma surgery, in frontal sinus surgery, in diabetic foot osteomyelitis surgery, in mastoid surgery, in oral and maxillofacial surgery in more than 4000 patients, with excellent clinical long‐term ...
Sebastian CE Lindfors, Chris JJ Arts, Nina C Lindfors   +2 more
wiley   +1 more source

Use of non-steroidal anti-inflammatory drugs and risk of Parkinson's disease: nested case-control study [PDF]

, 2011
Jane A. Driver, Giancarlo Logroscino, Leonard Lu, J. Michael Gaziano, Tobias Kurth   +4 more
openalex   +1 more source