Results 161 to 170 of about 9,961,334 (337)
BJGP OpenBackground: Overprescribing of potentially harmful medication in UK general practice has a complex association with socioeconomic deprivation. Aim: To assess trends in general practice prescribing of five high-risk medications and their relationship with
Tasneem Khan +6 more
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Advanced Science, EarlyView.Pd(II)/Cu(I) co‐catalyzed dual Csp2─Csp3 bonds construction from unactivated alkenes and arylsulfonyl chlorides to access benzo‐fused heterocycles with high efficiency and chemoselectivity. Abstract Transition‐metal‐catalyzed transformations offer a powerful approach to rapidly synthesize complex benzo‐fused heterocycles, crucial for drug and material ...
Jiahui Huang +9 more
wiley +1 more source
H‐2 AND NON ‐H‐2 DETERMINED STRAIN VARIATION IN PALATAL SHELF AND TONGUE ADENOSINE 3’:5’CYCLIC MONOPHOSPHATE: A POSSIBLE ROLE IN THE ETIOLOGY OF STEROID‐INDUCED CLEFT PALATE [PDF]
, 1979 Robert P. Erickson +2 more
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FABP4 as a Mediator of Lipid Metabolism and Pregnant Uterine Dysfunction in Obesity
Advanced Science, EarlyView.Obesity during late pregnancy contributes to uterine smooth muscle dysfunction, but the underlying mechanisms are unclear. This study identifies fatty acid binding protein 4 (FABP4) as a key player in the process, mediating excessive fatty acid uptake, lipid accumulation, and mitochondrial dysfunction in myometrial cells. FABP4 could be a novel uterine
Xuan Li +11 more
wiley +1 more source
APPLICATION OF SOLID DISPERSIONS WITH NON STEROIDAL ANTI INFLAMMATORY DRUGS IN PHARMACY
Разработка и регистрация лекарственных средств, 2019 The article provides a brief overview of the use of solid dispersions of NSAIDs with polymeric carriers. Solid dispersions are entered in various dosage forms for different purposes.
I. I. Krasnuk (Junior) +8 more
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Gut and Liver, 2012 Background/AimsAntithrombotic/nonsteroidal antiinflammatory drug (NSAID) therapies increase the incidence of upper gastrointestinal bleeding. The features of hemorrhagic peptic ulcer disease in patients receiving antithrombotic/NSAID therapies were ...
doaj +1 more source
The Misuse of Over-the-Counter NSAIDs [PDF]
, 2019 Over-the-counter nonsteroidal anti-inflammatory drugs (NSAIDs) are some of the most frequently used analgesics. The misuse of these medications occurs frequently and often without the patient’s realization.
Hudson, Sara
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Advanced Science, EarlyView.This study identifies a super‐enhancer‐driven transcriptional regulatory circuit comprising BCL6, SMAD3, and NFIB that cooperate to drive cholesterol synthesis via SREBF2/HMGCR/FDFT1 activation and regulate CDK2/CCND3 for cell cycle control. Targeting this circuit with BI‐3802 or downstream inhibitors (Fatostatin/Lovastatin) overcomes abiraterone ...
Liling Jiang +18 more
wiley +1 more source
‘Affinity’ chromatography of steroid-transforming enzymes with a non-steroidal ligand [PDF]
, 1979 A. G. Renwick +2 more
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Gut and Liver, 2016 Background/AimsThe interaction between nonsteroidal anti-inflammatory drugs (NSAIDs) and Helicobacter pylori remains controversial. We retrospectively investigated whether H.
doaj +1 more source