Results 171 to 180 of about 130,841 (291)

Arid1a Deficiency Drives Aristolochic Acid‐Induced Liver Tumorigenesis through Ctnnb1 Mutation and Defective Nucleotide Excision Repair

Advanced Science, EarlyView.
ARID1A is frequently mutated in both non‐malignant tissues and cancers, but its role in tumor development after exposure to genotoxic carcinogen remains unclear. It is found that aristolochic acid I accelerated liver tumorigenesis in ARID1A‐deficient context by impairing nucleotide excision repair and enhancing carcinogen bioactivation, revealing key ...
Lan Wang, Shi‐Hao Bai, Shu‐Jin Song, Xiao‐Li Zhang, Xue‐Ying Shang, Zhao‐Ning Lu, Xiao‐Fang Cui, Xin‐Le Zhu, Ze‐Guang Han   +8 more
wiley   +1 more source

Ischemic Colitis Induced by Concurrent Non-steroidal Anti-inflammatory Drug (NSAID) and Corticosteroid Use for Back Pain. [PDF]

Cureus
Almascati Y, Alhumaiqani A, Wen B, Alarayedh T.   +3 more
europepmc   +1 more source

Emerging Nanozyme Strategies for Precision Breast Cancer Treatment

Advanced Science, EarlyView.
Different types of nanozymes‐mediated chemotherapy, photothermal therapy, immunotherapy, and multiple combined therapies for the effective treatment of breast cancer. Abstract Breast cancer, the most common malignant tumor among women worldwide, poses a significant challenge to public health due to its high incidence and mortality rates.
Jian Zang, Zhaozhou Ren, Haibo Wang, Xing Yang, Yang Song, Jun Liao, Xiaoying Li   +6 more
wiley   +1 more source

Reduced Dose Perioperative Non-Steroidal Anti-Inflammatory Drugs in Arthroplasty Patients With Renal Impairment: A Five-Year Cohort Study. [PDF]

ANZ J Surg
Fernando-Canavan LTA, Stanny A, Richmond J, Mitchell DJ.   +3 more
europepmc   +1 more source

Antioxidant Carbon Dot of Selenomethionine Alleviates Oxidative Stress in Intervertebral Disc Degeneration

Advanced Science, EarlyView.
A selenomethionine‐derived carbon dot (Se‐Met‐CD) serves as a potent nano‐antioxidant, efficiently scavenging reactive oxygen species, protecting nucleus pulposus cells from oxidative damage, restoring extracellular matrix homeostasis, and significantly mitigating intervertebral disc degeneration in vivo, which demonstrates great promise as a nanozyme ...
Qingzheng Zhang, Zongtai Liu, Yirong Sun, Changfeng Fu, Jianxun Ding   +4 more
wiley   +1 more source

Long-Term Exposure to Non-Steroidal Anti-Inflammatory Medication in Relation to Dementia Risk. [PDF]

J Am Geriatr Soc
Vom Hofe I, Stricker BH, Ikram MK, Wolters FJ, Ikram MA.   +4 more
europepmc   +1 more source

Correction: Enteropathy induced by non-steroidal anti-inflammatory drugs [PDF]

, 1989

openalex   +1 more source

Spatial Transcriptomics and snRNA‐seq Expose CAF Niches Orchestrating Dual Stromal‐Immune Barriers in Hepatocellular Carcinoma

Advanced Science, EarlyView.
HmmyCAFs may form a triple immunosuppressive niche: possibly secrete ECM (POSTN, etc.) as physical barriers to block CD8⁺ T cells, induce CD8⁺ T exhaustion via those molecules, and use HIF‐1α‐driven metabolism to create acidic, nutrient‐poor microenvironments that suppress T cells.
Yingxue Li, Changxiang Huan, Haoting Sun, Wei Zhang, Zhen Guo, Chuanyu Li, Jia Yao, Zhiqi Zhang, Shizhe Yu, Qiongzhu Dong, Lunxiu Qin, Jinze Li, Lianqun Zhou   +12 more
wiley   +1 more source

Renal safety of Long-Term Non-steroidal Anti-inflammatory drugs use in patients with ankylosing spondylitis. [PDF]

Sci Rep
Kim YE, Park SY, Lee JS, Ha YJ, Yoo S, Kim S, Ahn SM, Hong S, Lee CK, Yoo B, Oh JS, Kim YG.   +11 more
europepmc   +1 more source

Benign stricture of the oesophagus: role of non-steroidal anti-inflammatory drugs.

, 1984
W E Wilkins, M G Ridley, A L Pozniak
openalex   +1 more source