Results 241 to 250 of about 221,273 (329)

Smart Nanoparticles Disrupting Energy Supply through Triple Mechanisms to Kill Tumors via Dual Disruption of Mitochondria and Lysosomes

Advanced Science, EarlyView.
This study introduces a biomimetic nanoplatform (MTCA@C) designed for precise cancer therapy. It targets mitochondria to induce dysfunction through photodynamic activation, while concurrently blocking mitophagy via lysosomal alkalinization. The platform further triggers methuosis, resulting in tumor cell death through vacuolization and energy pathway ...
Xiao Xu, Qiqing Huang, Yang Liu, Jinzhuo Liu, Deyi Yang, Yanni Song, Xin Han   +6 more
wiley   +1 more source

Comparative efficacy of non-steroidal anti-inflammatory drugs in preventing postoperative macular edema following cataract surgery: a systematic review and Network Meta-analysis. [PDF]

Int J Ophthalmol
Lang M, Xuan J, Li X, Liu MM, Xu J, Liu T.   +5 more
europepmc   +1 more source

In Situ Assembly of Transformable Monopeptide on Activated Neutrophils Attenuates NETs‐Induced Hepatocellular Carcinoma Metastasis by Disrupting NE Nuclear Translocation

Advanced Science, EarlyView.
Activated neutrophils release extracellular traps (NETs) that promote tumor metastasis. FTP‐NPs are develpoed, a peptidic nanomaterial that binds NE on neutrophil membranes, forming NE‐fibril clusters that deactivate NE and prevent NETs formation. This strategy reduces metastasis and enhances the anti‐tumor immune response by targeting NE subcellular ...
Yichi Chen, Yijun Wang, Haitao Shang, Jiayue Qiu, Ruotian Zhang, Yuxiang Xiong, Tong Wang, Fengyi Wang, Anbang Wu, Xin Lin, Bolin Wu, Chen Huang, Wen Cheng, Lu Zhang   +13 more
wiley   +1 more source

Associations of genetic proxies for non-steroidal anti-inflammatory drugs with increased kidney stone risk: a Mendelian randomization study. [PDF]

Inflammopharmacology
Liu J, Dong K, Qin G, Ye C, Wu J, Wang E, Dong Z.   +6 more
europepmc   +1 more source

WCN25-907 CLINICAL CHARACTERISTICS IN CHILDREN WITH MONOGENIC AND NON-GENETIC STEROID-RESISTANT NEPHROTIC SYNDROME DUE TO FOCAL SEGMENTAL GLOMERULOSCLEROSIS TREATED WITH CALCINEURIN INHIBITORS

Larisa Prikhodina
openalex   +1 more source

Self-prescription of paracetamol and non-steroidal anti-inflammatory drugs among health science undergraduate students in Imam Abdulrahman Bin Faisal University

, 2019
Lama A. Almuhaish, Ranya H. Sabri, Norah K. AlAbdulwahab, Mona M. AlMubayid, Hedayh A. AlZaher   +4 more
openalex   +1 more source

Polystyrene Microplastics Exposure Aggravates Clear Cell Renal Cell Carcinoma Progression via the NF‐κB and TGF‐β Signaling Pathways

Advanced Science, EarlyView.
This research provides the first comprehensive evidence that PS‐MPs exacerbate ccRCC progression by activating the NF‐κB and TGF‐β pathways. These findings establish PS‐MPs as an environmental risk factor for ccRCC progression and identify the NF‐κB and TGF‐β signaling as potential therapeutic targets to mitigate the adverse effects of ‐PS‐MPs exposure.
Shiqi Ye, Jianfeng Xiang, Siqi Zhou, Qintao Ge, Aihetaimujiang Anwaier, Kun Chang, Gang Wei, Jiahe Lu, Xi Tian, Shuxuan Zhu, Yuchen Jiang, Wei Zhang, Tingting Cai, Moran Xu, Dingwei Ye, Danfeng Xu, Tao Wang, Hailiang Zhang, Wenhao Xu   +18 more
wiley   +1 more source

Assessment of non-steroidal anti-inflammatory drugs use and its complications among pediatric patients at a private tertiary care hospital in Malaysia. [PDF]

BMC Pediatr
Low JYC, Sivanandy P, Ingle PV, Manirajan P.   +3 more
europepmc   +1 more source

3P A steroid-based liquid biopsy for differentiating ovarian cancer from non-malignant adnexal masses

Marija Gjorgoska, Boštjan Pirš, Špela Smrkolj, Tea Lanišnik Rižner   +3 more
openalex   +2 more sources

A Supramolecular Nanoscavengers: Based “Cargo‐Exchange” Breaking Cholesterol Metabolic Dysregulation for Glioblastoma Therapy

Advanced Science, EarlyView.
Dysregulated cholesterol metabolism, driven by a complex array of mechanisms, is a defining characteristic of glioblastoma (GBM). In this study, supramolecular nanoscavengers are engineered by harnessing the intrinsic binding affinity between endogenous small‐molecule cholesterol and β‐cyclodextrin (β‐CD).
Zonghua Tian, Yun Chen, Jingyi Zhou, Shilin Zhang, Hongrui Fan, Xuwen Li, Tao Sun, Chen Jiang   +7 more
wiley   +1 more source