Results 261 to 270 of about 130,841 (291)
Non‐steroidal anti‐inflammatory drugs [PDF]
Medical Journal of Australia, 1995 The elderly are at higher risk of adverse reactions from non-steroidal anti-inflammatory drugs (NSAIDs), including those due to drug interactions, than younger people. Before prescribing oral NSAIDs in the elderly, the clinician should consider other forms of therapy and topical NSAIDs.
David I. Quinn +2 more
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A Non-Steroidal Facial Amphiphile
Journal of the American Chemical Society, 2006This paper gives the synthesis of an unusual non-steroidal amphiphile consisting of a large rigid molecule that possesses two water-solubilizing sulfates on one face and an extended hydrophobic surface on the other. The properties of this compound have been examined by X-ray analysis, light and cryo-electron microscopy, surface tension, conductivity ...
Jennifer L. Sorrells, Fredric M. Menger
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Non-Steroidal Anti-Inflammatory Drugs
Rheumatology, 1993Pre-clinical studies suggest that, whilst NSAIDs have similar anti-inflammatory efficacy, the potential for producing side effects varies widely between members of this class of therapeutic agents. The ways in which NSAIDs produce one of their most serious side effects, gastrointestinal damage, are outlined and consideration is given to ways of ...
lain N. Taylor, Gavin N. C. Kenny
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Follicular Non-Steroidal Regulators [PDF]
, 1979 Chemical messengers synthesized both within and without the ovary control follicular and oocyte maturation and ovulation. The extraovarian messengers, whose roles are better defined, are the pituitary gonadotropins-luteinizing hormone (LH) and follicle stimulating hormone (FSH).
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1999
Endogenous estrogens, such as 17β-estradiol (1, Scheme 1), have long been recognized as the primary hormones involved in the development and maintenance of the female sex organs, mammary glands and other sexual characteristics. More recently, their involvement in the growth and/or function of a number of other tissues, such as the skeleton, the ...
J. A. Dodge, C. D. Jones
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Endogenous estrogens, such as 17β-estradiol (1, Scheme 1), have long been recognized as the primary hormones involved in the development and maintenance of the female sex organs, mammary glands and other sexual characteristics. More recently, their involvement in the growth and/or function of a number of other tissues, such as the skeleton, the ...
J. A. Dodge, C. D. Jones
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In vitro bioassays of non-steroidal phytoestrogens
The Journal of Steroid Biochemistry and Molecular Biology, 1993Some of the isoflavonoids present in human diet as well as in urine are expected to exert biologic effects as they have been reported to bind to estrogen receptors and to be estrogenic in other species. This report describes the in vitro assessment of estrogenic effects of isoflavonoids using human endometrial cells and tissue.
Herman Adlercreutz +3 more
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Perioperative analgesia with non-steroidal analgesics
Current Opinion in Anaesthesiology, 1998Non-steroidal anti-inflammatory drugs are widely used for perioperative analgesia as a sole analgesic after minor surgical procedures and in combination with other types of analgesics after major surgery. The development and use of new selective cyclo-oxygenase-2 inhibitors hopefully reduce the likelihood of perioperative adverse effects that may ...
P. Tarkkila, Per H. Rosenberg
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Non-Steroidal Steroid Receptor Modulators
Current Medicinal Chemistry, 2005The last ten years much attention has been focused on the finding of non-steroidal ligands for steroidal nuclear receptors for reasons such as diminishing cross-reactivity to eliminate side effect profiles, changing physicochemical properties which might cause different tissue distribution profiles and altering binding modes which influence the binding
Pedro H. H. Hermkens +4 more
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Non-steroidal progesterone receptor modulators
Expert Opinion on Therapeutic Patents, 2003Progesterone (P4) plays an essential role in female reproduction and progesterone receptor (PR) agonists have been used in female contraceptives and in postmenopausal hormone therapy. Recent studies in women and non-human primates show that PR antagonists may also have potential as contraceptive agents and for the treatment of various gynaecological ...
Zhiming Zhang +4 more
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Non-steroidal anti-inflammatory drugs
2013Several DSC studies have given a better understanding of the molecular mechanisms of interaction of many non-steroidal anti-inflammatory agents (NSAIDs), such as indomethacin, ibuprofen, naproxen, nimesulide, ketoprofen and oxicam drugs with cell membranes or with simplified phospholipid-based biomembrane models.The consequent changes in the ...
CARBONE, CLAUDIA +2 more
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