Results 261 to 270 of about 122,879 (287)
Follicular Non-Steroidal Regulators [PDF]
, 1979 Chemical messengers synthesized both within and without the ovary control follicular and oocyte maturation and ovulation. The extraovarian messengers, whose roles are better defined, are the pituitary gonadotropins-luteinizing hormone (LH) and follicle stimulating hormone (FSH).
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1999
Endogenous estrogens, such as 17β-estradiol (1, Scheme 1), have long been recognized as the primary hormones involved in the development and maintenance of the female sex organs, mammary glands and other sexual characteristics. More recently, their involvement in the growth and/or function of a number of other tissues, such as the skeleton, the ...
J. A. Dodge, C. D. Jones
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Endogenous estrogens, such as 17β-estradiol (1, Scheme 1), have long been recognized as the primary hormones involved in the development and maintenance of the female sex organs, mammary glands and other sexual characteristics. More recently, their involvement in the growth and/or function of a number of other tissues, such as the skeleton, the ...
J. A. Dodge, C. D. Jones
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In vitro bioassays of non-steroidal phytoestrogens
The Journal of Steroid Biochemistry and Molecular Biology, 1993Some of the isoflavonoids present in human diet as well as in urine are expected to exert biologic effects as they have been reported to bind to estrogen receptors and to be estrogenic in other species. This report describes the in vitro assessment of estrogenic effects of isoflavonoids using human endometrial cells and tissue.
Herman Adlercreutz +3 more
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Perioperative analgesia with non-steroidal analgesics
Current Opinion in Anaesthesiology, 1998Non-steroidal anti-inflammatory drugs are widely used for perioperative analgesia as a sole analgesic after minor surgical procedures and in combination with other types of analgesics after major surgery. The development and use of new selective cyclo-oxygenase-2 inhibitors hopefully reduce the likelihood of perioperative adverse effects that may ...
P. Tarkkila, Per H. Rosenberg
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Non-Steroidal Steroid Receptor Modulators
Current Medicinal Chemistry, 2005The last ten years much attention has been focused on the finding of non-steroidal ligands for steroidal nuclear receptors for reasons such as diminishing cross-reactivity to eliminate side effect profiles, changing physicochemical properties which might cause different tissue distribution profiles and altering binding modes which influence the binding
Pedro H. H. Hermkens +4 more
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Non-steroidal progesterone receptor modulators
Expert Opinion on Therapeutic Patents, 2003Progesterone (P4) plays an essential role in female reproduction and progesterone receptor (PR) agonists have been used in female contraceptives and in postmenopausal hormone therapy. Recent studies in women and non-human primates show that PR antagonists may also have potential as contraceptive agents and for the treatment of various gynaecological ...
Zhiming Zhang +4 more
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Non-steroidal interference with male fertility
Advances in Contraception, 1986This review addresses the varied history of male contraception as it applies to nonsteroidal materials. Some of the antispermatogenic agents discussed are 1) hormonally active agents; 2) luteinizing hormone-releasing hormone analogs; 3) non-hormonal agents such as nitrofurans alkylating agents thiophenes bis-diamines dinintropyrroles fluoroacetamide 1-
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Non-Steroidal Subtype Selective Estrogens
Current Medicinal Chemistry, 2005The biological effects of estrogens are thought to be mediated by two receptors referred to as ERalpha and ERbeta. In recent years significant efforts have been devoted to the design of subtype selective ligands. These ligands are valuable tools to establish the precise biological role of each of the subtypes and to develop new generations of ...
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Evaluating Non-steroidal Antiinflammatory Drugs
Scandinavian Journal of Rheumatology, 1988Non-steroidal antiinflammatory drugs (NSAID) are important for many reasons. First, due to their proven analgesic and antiinflammatory effects, they are important to the patients who need them for symptomatic improvement of various painful conditions (1).
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2 Non-Steroidal Anti-Inflammatory Drugs
1967Publisher Summary This chapter explores that the study of inflammation and anti-inflammatory drugs gained considerable impetus from the demonstration in 1949 of the antirheumatic action of cortisone. Despite a considerable amount of research and an even greater amount of speculation, the mechanism of action of anti-inflammatory compounds is still ...
S S Adams, R Cobb
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