Results 41 to 50 of about 221,273 (329)

Vibrational properties of inclusion complexes: the case of indomethacin-cyclodextrin

, 2006
Vibrational properties of inclusion complexes with cyclodextrins are studied by means of Raman spectroscopy and numerical simulation. In particular, Raman spectra of the non-steroidal, anti-inflammatory drug indomethacin undergo notable changes in the ...
Anderson A., Barbara Rossi, Choi S. H., Gabriele Viliani, Giorgina Scarduelli, Graziano Guella, Ines Mancini, Lee A. S., Paolo Verrocchio   +8 more
core   +1 more source

Developing a complex intervention to improve prescribing safety in primary care:mixed methods feasibility and optimisation pilot study [PDF]

, 2014
Objectives (A) To measure the extent to which different candidate outcome measures identified high-risk prescribing that is potentially changeable by the data-driven quality improvement in primary care (DQIP) intervention.(B) To explore the value of ...
Dreischulte, Tobias, Grant, Aileen M., Guthrie, Bruce   +2 more
core   +6 more sources

Non-Steroidal Antiinflammatory Drugs

International Journal of Advanced Research in Science, Communication and Technology, 2022
Nonsteroidal anti-inflammatory drugs, or NSAIDs, are among the most often prescribed pain relievers. NSAIDs are a highly successful medicine class for pain and inflammation, but they are also known to cause gastrointestinal bleeding, cardiovascular side effects, and NSAID-induced nephrotoxicity.
null Prof. V. V. Nimbalkar, null Dr. P M. Gaikwad, null Gauri P. Shinde, null Simran M. Jaggi, null Snehal S. Jogdand, null Kalyani S. Mhaismale   +5 more
openaire   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Analysis of the use and adverse effects of non-steroidal anti-inflammatory drugs: A pilot study [PDF]

Vojnosanitetski Pregled, 2006
Background/Aim. The use and adverse effects of nonsteroidal anti-inflammatory drugs (NSAIDs) in outpatients with rheumatic diseases has not yet been studied enough.
Perić Aneta, Toskić-Radojičić Marija
doaj   +1 more source

Etoricoxib Coated Tablets: Bioequivalence Assessment between Two Formulations Administered under Fasting Conditions

Pharmaceutics, 2023
Etoricoxib is a non-steroidal anti-inflammatory drug with high selectivity for cyclooxygenase 2 (COX-2), exerting a pronounced anti-inflammatory effect with fewer adverse events when compared to COX-1 inhibitors.
Jessica Meulman, Marcelo Gomes Davanço, Débora Renz Barreto Vianna, Thalita Martins da Silva, Fernando Costa, Fernando Bastos Canton Pacheco, Milla Emke de Oliveira, Celso Francisco Pimentel Vespasiano   +7 more
doaj   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Potential Strategies in the Prevention of Nonsteroidal Anti-inflammatory Drugs-Associated Adverse Effects in the Lower Gastrointestinal Tract

Gut and Liver, 2020
With the increasing use of nonsteroidal anti-inflammatory drugs (NSAIDs), the incidence of lower gastrointestinal (GI) complications is expected to increase.
Chuan-Guo Guo, Wai K. Leung
doaj   +1 more source

A pharmacokinetic comparison of three pharmaceutical formulations of nimesulide in healthy volunteers [PDF]

Vojnosanitetski Pregled, 2005
Background/Aim. Switching the patient from one pharmaceutical formulation of the same drug to another, may lead to therapeutic inadequancy in some cases. To minimize the risk, careful pharmacokinetic studies are desired in the pre-registration period and
Jovanović Dušan, Kilibarda Vesna, Todorović Veljko, Potrebić Olivera   +3 more
doaj   +1 more source

Transcriptomic effects of the non-steroidal anti-inflammatory drug Ibuprofen in the marine bivalve Mytilus galloprovincialis Lam [PDF]

, 2016
The transcriptomic effects of Ibuprofen (IBU) in the digestive gland tissue of Mytilus galloprovincialis Lam. specimens exposed at low environmental concentrations (250 ng L-1) are presented. Using a 1.7 K feature cDNA microarray along with linear models
Amorim, Monica J. B., Bebianno, Maria João, Dondero, Francesco, Maria, Vera L.   +3 more
core   +1 more source