Results 61 to 70 of about 213,082 (269)

Tauroursodeoxycholic Acid Inhibits Nuclear Factor Kappa B Signaling in Gastric Epithelial Cells and Ameliorates Gastric Mucosal Damage in Mice

open access: yesThe Korean Journal of Gastroenterology, 2022
Background/Aims: Previous studies have reported the protective effects of tauroursodeoxycholic acid (TUDCA) on gastric epithelial cells in some animal models, but the precise mechanisms are unclear.
Su Hwan Kim   +10 more
doaj   +1 more source

Real‐World Investigation of Satralizumab in Patients With Neuromyelitis Optica Spectrum Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Satralizumab, a monoclonal antibody targeting the interleukin‐6 receptor, has demonstrated efficacy in clinical trials for neuromyelitis optica spectrum disorder (NMOSD). However, its real‐world effectiveness and safety compared to conventional immunosuppressive therapies remain uncertain.
Li‐Tsung Lin   +2 more
wiley   +1 more source

Olink Proteomics Analysis Reveals Heterogeneous Responses to FcRn Blockade in Anti‐AChR Antibody‐Positive Myasthenia Gravis: FGF‐19 as a Novel Biomarker

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to systematically observe the clinical manifestations, immune cell subsets, and dynamic changes in serological indicators in patients with myasthenia gravis (MG) before and after efgartigimod (EFG) treatment. Methods We analyzed the baseline data, laboratory parameters, and lymphocyte subset proportions in MG ...
Tiancheng Luo   +9 more
wiley   +1 more source

Risks and benefits of asthma therapies

open access: yesAllergology International, 2000
Maintenance use of short-acting adrenergic agents can cause tachyphylaxis, increased non-specific bronchial hyperreactivity, poorer clinical control, a worsened late allergic reaction and possibly an increased risk of death; therefore, 'as needed' use is
Peter König
doaj   +1 more source

Helicobacter pylori Eradication in Drug-related Peptic Ulcer

open access: yesThe Korean Journal of Gastroenterology, 2020
Non-steroidal anti-inflammatory drugs (NSAIDs) and aspirin are the most frequently prescribed drugs worldwide, and their long-term use often leads to peptic ulcers (PUs) along with serious complications, such as bleeding and perforation.
Moon Kyung Joo
doaj   +1 more source

Nonsteroidal Anti-Inflammatory Drugs and Ectodomain Shedding of the Amyloid Precursor Protein [PDF]

open access: yes, 2008
Background: Epidemiological studies have suggested that long-term use of nonsteroidal anti-inflammatory drugs (NSAIDs) is associated with a reduced incidence of Alzheimer's disease (AD).
Czirr, Eva   +8 more
core   +1 more source

Life‐Threatening Bradycardia in Anti‐NMDA‐Receptor Encephalitis and a Novel Use for Permanent Pacing

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Pediatric anti‐NMDA receptor encephalitis (pNMDARE) is an autoantibody‐mediated disorder that can cause severe autonomic dysfunction, including symptomatic bradycardia and asystole. Dysautonomia can last for years, making it very challenging to manage.
Sarah Tucker   +9 more
wiley   +1 more source

Nonsteroid anti-inflammatory drugs [PDF]

open access: yesEinstein (São Paulo), 2008
Non-steroidal anti-infl ammatory drugs are the most frequentlyprescribed medications worldwide. In the United States, around 17million people use daily these drugs, because many of them canbe bought as over the counter medication, and approximately ...
Wiliam Habib Chahade   +2 more
doaj  

Prevention of Non-steroidal Anti-inflammatory Drug-induced Peptic Ulcers

open access: yesThe Korean Journal of Gastroenterology, 2020
Nonsteroidal anti-inflammatory drugs (NSAID) are some of the most commonly prescribed medications in clinical practice. The long-term use of NSAIDs is one of the main causes of peptic ulcers and the increased risk of upper gastrointestinal tract ...
Seong Jun Chu   +2 more
doaj   +1 more source

Prediction of aromatase inhibitory activity using the efficient linear method (ELM) [PDF]

open access: yes, 2015
Aromatase inhibition is an effective treatment strategy for breast cancer. Currently, several in silico methods have been developed for the prediction of aromatase inhibitors (AIs) using artificial neural network (ANN) or support vector machine (SVM). In
Nantasenamat, Chanin   +3 more
core  

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