Results 71 to 80 of about 214,597 (337)
Feasibility of recruitment to an oral dysplasia trial in the United Kingdom [PDF]
Background: Oral epithelial dysplasia (OED) has a malignant potential. Therapeutic options for OED remain both limited and without good evidence. Despite surgery being the most common method of treating OED, recurrence and potentially significant ...
Dunn, Janet A.+3 more
core +2 more sources
The Associations Between Chronic Active Lesions and White Matter Disease: A 7 Tesla Imaging Study
ABSTRACT Background The relationship between paramagnetic rim lesions (PRLs) and surrounding normally appearing white matter (NAWM) disease, potentially contributory to the associations seen between PRLs and clinical impairment, is underexplored. Objectives To assess whether PRLs correlate with a greater degree of NAWM injury in early MS.
Ellie McCluey+17 more
wiley +1 more source
Prevention of Non-steroidal Anti-inflammatory Drug-induced Peptic Ulcers
Nonsteroidal anti-inflammatory drugs (NSAID) are some of the most commonly prescribed medications in clinical practice. The long-term use of NSAIDs is one of the main causes of peptic ulcers and the increased risk of upper gastrointestinal tract ...
Seong Jun Chu+2 more
doaj +1 more source
Non-steroid agents for idiopathic pulmonary fibrosis
Idiopathic pulmonary fibrosis is a chronic progressive lung disease with poor outcome and no effective treatment to date. This is an update of a Cochrane Review first published in 2003.To assess the efficacy of non-steroid agents in adults with idiopathic pulmonary fibrosis.We searched the Cochrane Airways Group Register (30 March 2010), the Cochrane ...
SPAGNOLO, Paolo+7 more
openaire +6 more sources
ABSTRACT Introduction The kappa‐free light chain (κ‐FLC) index is known to be highly sensitive and specific for diagnosing multiple sclerosis (MS), while little is understood about lambda (λ)‐FLC. This study assessed the κ‐FLC and λ‐FLC indices in autoimmune glial fibrillary acidic protein (GFAP) astrocytopathy.
Michael Levraut+11 more
wiley +1 more source
Synthesis of 1 alpha,25-Dihydroxyvitamin D Analogues Featuring a S-2-symmetric CD-ring Core [PDF]
Three analogues of 1 alpha,25-dihydroxyvitamin D-3 (calcitriol), featuring a transfused decalin C, D-core with local S-2-symmetry, and possessing identical side-chain and seco-B,A-ring structures, have been synthesized starting from readily available ...
De Clercq, Pierre, Minne, Garrett
core +2 more sources
ABSTRACT Background Bladder dysfunction affects over 85% of people with multiple sclerosis (PwMS), yet current assessment methods are limited to periodic in‐clinic evaluations or subjective patient reports, failing to capture real‐world symptom fluctuations.
Valerie J. Block+8 more
wiley +1 more source
Clinical Characteristics of Parkinsonism in HTLV‐1‐Associated Myelopathy
ABSTRACT Objective Human T‐lymphotropic virus type 1 (HTLV‐1)‐associated myelopathy/tropical spastic paraparesis (HAM/TSP) is the classic neurological manifestation of HTLV‐1 infection; however, this virus has also been associated with other neurological disorders. Concurrent parkinsonism is relatively rare and presents diagnostic challenges.
Mika Dozono+8 more
wiley +1 more source
PEPTIC ULCER FREQUENCY DIFFERENCES RELATED TO H. PYLORI OR AINES
Background Peptic ulcer etiology has been changing because of H. pylori decline. Objectives To estimate peptic ulcer prevalence in 10 years-interval and compare the association with H. pylori and use of non-steroidal anti-inflammatory drugs.
Diego Michelon de CARLI+4 more
doaj +1 more source
Efficacy of NSAIDs for the prevention of acute mountain sickness: a systematic review and meta-analysis [PDF]
Background: Acute mountain sickness (AMS) can occur in anyone going to a high altitude. Non-steroidal anti-inflammatory drugs (NSAIDs) have been studied for the prevention of AMS with mixed results. In this systematic review, we analyze all existing data
Anil Pandit+4 more
doaj +1 more source