Results 81 to 90 of about 122,879 (287)
Effect of nonsteroidal anti-inflammatory drug Rofecoxib (Vioxx™) on the bone repair [PDF]
Objective: To evaluate the effect of the nonsteroidal anti-inflammatory drug Rofecoxib (Vioxx™) on the bone repair process in the tibiae of stressed rats.
Luiz Alberto Milanezi+2 more
doaj
This work utilizes spatial transcriptomics to map the transcriptional landscape of adenomyosis with obvious invagination structure from the invaginating site to deep lesions. By integrating with single‐cell RNA sequencing, this study elucidates the molecular features of invagination, invasion, and fibrosis, and finds the major participants and vital ...
Boyu Li+19 more
wiley +1 more source
Diaryloxazole and Diarylthiazolealkanoic Acids: Two Novel Series of Non-steroidal Anti-inflammatory Agents [PDF]
Kristen Brown+3 more
openalex +1 more source
Machine Learning‐Enabled Drug‐Induced Toxicity Prediction
Unexpected toxicity accounts for 30% of drug development failures. This review highlights ML innovations in predicting drug‐induced toxicity, emphasizing comparative analyses, interpretable algorithms, and multi‐source data integration. It categorizes toxicity types, summarizes ML models, and organizes key databases, offering strategies to address ...
Changsen Bai+5 more
wiley +1 more source
Regulatory effect of gut microbes on blood pressure
The interaction between gut microbiota and hypertension, the genera which affect the blood pressure in taxonomic level, and the commonly used treatments to hypertension based on the gut microbes were summarized in this review. The increases of Lactobacillus, etc.
Dong Yan+6 more
wiley +1 more source
Marcel Nel,1 Anna M Joubert,1 Wolfgang Dohle,2 Barry VL Potter,2 Anne E Theron1 1Department of Physiology, Faculty of Health Sciences, University of Pretoria, Pretoria, South Africa; 2Medicinal Chemistry & Drug Discovery, Department of Pharmacology,
Nel M+4 more
doaj
Extracts from "Clinical Evidence": Non-steroidal anti-inflammatory drugs
Definition Non-steroidal anti-inflammatory drugs (NSAIDs) have anti-inflammatory, analgesic, and antipyretic effects and inhibit thrombocyte aggregation. The drugs have no documented effect on the disease process itself. Incidence/prevalence NSAIDs are widely used.
openaire +5 more sources
‘Chondroprotection’ by non-steroidal anti-inflammatory drugs. [PDF]
Non steroidal anti-inflammatory drugs may influence the osteoarthritis process osteoarthritis is a dynamic, metabolically active remodelling process with potential to compensate for a variety of triggering insults.
openaire +2 more sources
Single‐Cell Atlas Reveals Tumorigenic Profiles and Immune Dynamics of Adrenal Incidentalomas
Single‐cell RNA sequencing reveals cellular heterogeneity in adrenal incidentalomas, identifying distinct tumor cell populations. Clusterin is recognized as a biomarker for adrenocortical tumors, correlating with established markers. MYCN‐positive clusters in pheochromocytomas indicated poorer survival.
Meng Wang+18 more
wiley +1 more source
THE EFFECT OF NON‐STEROIDAL ANTI‐INFLAMMATORY DRUGS ON HISTAMINE FORMATION IN THE RAT [PDF]
A. G. RADWAN, G.B. West
openalex +1 more source