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Non-steroidal anti-inflammatory drugs
2013Several DSC studies have given a better understanding of the molecular mechanisms of interaction of many non-steroidal anti-inflammatory agents (NSAIDs), such as indomethacin, ibuprofen, naproxen, nimesulide, ketoprofen and oxicam drugs with cell membranes or with simplified phospholipid-based biomembrane models.The consequent changes in the ...
CARBONE, CLAUDIA+2 more
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2 Non-Steroidal Anti-Inflammatory Drugs
1967Publisher Summary This chapter explores that the study of inflammation and anti-inflammatory drugs gained considerable impetus from the demonstration in 1949 of the antirheumatic action of cortisone. Despite a considerable amount of research and an even greater amount of speculation, the mechanism of action of anti-inflammatory compounds is still ...
S S Adams, R Cobb
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Non-steroidal anti-inflammatory drugs
2003Introduction ___________________________________________________________ 419 Prostaglandins and renal function __________________________________________ 420 The prostaglandin pathway 420 Renal prostanoid receptors 421 Cyclooxygenase isoforms _________________________________________________ 422 Factors regulating isoform expression 422 Distribution ...
Ali J. Olyaei+3 more
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Non-steroidal Anti-inflammatory Drugs and Hypertension
Cell Biochemistry and Biophysics, 2013Non-steroidal anti-inflammatory drugs (NSAIDs) are frequently used to alleviate pain of the patients who suffer from inflammatory conditions like rheumatoid arthritis, osteoarthritis, and other painful conditions like gout. This class of drugs works by blocking cyclooxgenases which in turn block the prostaglandin production in the body.
Liuying Zheng, Xinping Du
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Non-steroidal anti-inflammatory drugs and the heart
Heart, 2010Older patients are the most likely to use non-steroidal anti-inflammatory drugs (NSAIDs) and are at the highest risk of developing incident heart failure. In their paper published in this issue of Heart , von den Hondel et al 1 present imaging data from the Rotterdam Study highlighting the phenotypic manifestation of NSAID use on the heart, with ...
Ashish Aneja, Michael E. Farkouh
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Interactions of non-steroidal anti-inflammatory drugs
Baillière's Clinical Rheumatology, 1988As NSAIDs are commonly used in patients receiving concomitant drug therapy, there is a risk of clinically significant drug interactions. Important interactions with NSAIDs involve one or both of two major mechanisms: pharmacokinetic (e.g. lithium, phenytoin and barbiturates) and pharmacodynamic (e.g. antihypertensive agents, diuretics). Prescription of
M.H. Lindon Wing, Anne L. Tonkin
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Non-steroidal anti-inflammatory drugs
1986This is a group of drugs with analgesic, antipyretic and anti-inflammatory properties whose main role is to provide symptomatic relief of pain and stiffness in various rheumatic and other conditions. In 1980 these drugs accounted for 5% of all patient prescriptions and around 10% of the total ingredient cost of all drugs (McLean, 1983).
David M. Grennan, Carol Higham
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Non-steroidal Anti-Inflammatory Drugs and Melanoma
Current Pharmaceutical Design, 2012Inflammation is an important contributor to the development and progression of all human cancers. Inflammatory lipid metabolites, prostaglandins, formed from arachidonic acid by prostaglandin H synthases commonly called cyclooxygenases (COXs), bind to specific receptors that activate signaling pathways driving to the development and progression of ...
Antonio Martorell-Calatayud+2 more
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Hypersensitivities to non-steroidal anti-inflammatory drugs
Expert Review of Clinical Immunology, 2014NSAIDs are the most commonly used medications worldwide and are responsible for almost 25% of adverse drug reactions. Such reactions can have different manifestations and can be immunologic or non-immunologic. The diagnosis is primarily based on the medical history, which can be difficult in patients receiving multiple medications. Because skin testing
Sami L. Bahna, Ahmad A. Mourad
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Non-steroidal anti-inflammatory drugs for the common cold
Cochrane Database of Systematic Reviews, 2009Non-steroidal anti-inflammatory drugs (NSAIDs) have been widely used for the treatment of pain and fever associated with the common cold.To determine the effects of NSAIDs versus placebo (and other treatments) on signs and symptoms of the common cold, and to determine any adverse effects of NSAIDs in people with the common cold.We searched CENTRAL ...
Yoon Jung Chang+4 more
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