Results 161 to 170 of about 34,491,299 (291)

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

From Alpine Snow to Mediterranean Rivers: Non-Target Analysis of CECs in Contrasting Aquatic Environments

Contaminants of emerging concern (CECs) are increasingly detected in aquatic environments, including remote areas. Non-target analysis based on high-resolution mass spectrometry is a powerful strategy for characterizing complex mixtures, identifying ...
Alessia Fabbris, Arianna Ghignone, Masho Hilawie Belay, A. Arques, Mónika Adányi, Manuel A. Andino-Enriquez, I. Vallés, Paola Calza, Emilio Marengo, Elisa Robotti   +9 more
core  

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Visual target tracking via weighted non-sparse representation and online metric learning

, 2013
In this paper, we propose online metric learning tracking method that consider visual tracking as a similarity measurement problem, and incorporates adaptive metric learning and generative histogram model based on non-sparse linear representation into ...
Duan, Jingdi, Fan BJ(范保杰), Cong Y(丛杨)   +2 more
core  

Large-scale generation of in silico based spectral libraries to annotate dark chemical space features in non-target analysis. [PDF]

Anal Bioanal Chem
Egede Frøkjær E, Hansen M.
europepmc   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Enhancing the Detectable Chemical Space in an Effluent-Dominated Stream: Non-Target Analysis Reveals Potential Rapid <i>In Situ</i> Product Formation. [PDF]

Environ Sci Technol Lett
Mianecki AL, LeFevre GH.
europepmc   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

COMPREHENSIVE NON-TARGET SCREENING OF ALPINE SNOW AND SURFACE WATERS BY COMPLEMENTARY LC-HRMS AND GC-MS

Introduction Non-target screening (NTS) by high-resolution mass spectrometry (HRMS) has become a key approach for comprehensive characterization of complex environmental samples, including snow matrices.
Alessia Fabbris, Arianna Ghignone, Masho Hilawie Belay, Paola Calza, Manuel Andino-Enriquez, Emilio Marengo, Monika Adanyi, Elisa Robotti   +7 more
core  

FluoroMatch: A Comprehensive Software for Non-Targeted PFAS Analysis

ISEE Conference Abstracts, 2021
Paul Stelben, Jeremy P. Koelmel, Carrie A. Mcdonough, David A. Dukes, Juan J. Aristizabal Henao, Sara L. Nason, Yang Li, Sandi Sternberg, Elizabeth Lin, Manfred Beckmann, Antony J. Williams, John Draper, Jasen Finch, Chris Deigl, Emma E. Rennie, John A. Bowden, Krystal Godri Pollitt   +16 more
openaire   +1 more source