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The Relationship between Exposome and Microbiome

Microorganisms
Currently, exposome studies include a raft of different monitoring tools, including remote sensors, smartphones, omics analyses, distributed lag models, etc.
Antonino De Lorenzo, Laura Di Renzo, David Della-Morte   +2 more
exaly   +3 more sources

Defining the Exposome Using Popular Education and Concept Mapping With Communities in Atlanta, Georgia

Frontiers in Public Health, 2022
IntroductionThe exposome concept provides a framework to better incorporate the environment into the study of health and disease and has been defined by academics to encompass all lifetime exposures including toxicants, diet, and lifestyle choices ...
Erin Lebow-Skelley, Lynne Young, Lynne Young, Yomi Noibi, Yomi Noibi, Karla Blaginin, Karla Blaginin, Margaret Hooker, Dana Williamson, Martha Scott Tomlinson, Michelle C. Kegler, Melanie A. Pearson   +11 more
doaj   +1 more source

Impact of perinatal environmental health education intervention on exposure to endocrine disruptors during pregnancy—PREVED study: study protocol for a randomized controlled trial

Trials, 2021
Background The suspected or actual effects on health of endocrine-disrupting chemicals (EDC) and their ubiquitous presence in everyday life justify the implementation of health promotion interventions. These interventions should ideally be applied during
Houria E. L. Ouazzani, Steeve Rouillon, Nicolas Venisse, Lynda Sifer-Rivière, Antoine Dupuis, Guillaume Cambien, Sarah Ayraud-Thevenot, Anne-Sophie Gourgues, Pascale Pierre-Eugène, Fabrice Pierre, Sylvie Rabouan, DisProSE Group, Virginie Migeot, Marion Albouy-Llaty   +13 more
doaj   +1 more source

Estimating Aggregate Environmental Risk Score in Psychiatry: The Exposome Score for Schizophrenia

Frontiers in Psychiatry, 2021
To understand the role of environment in the pathoetiology of psychosis spectrum disorders, research has thus far mainly investigated the effects of single exposures in isolation, such as the association between cannabis use and schizophrenia.
Lotta-Katrin Pries, Gamze Erzin, Bart P. F. Rutten, Jim van Os, Jim van Os, Jim van Os, Sinan Guloksuz, Sinan Guloksuz, Sinan Guloksuz   +8 more
doaj   +1 more source

The exposome and the future of epidemiology: a vision and prospect [PDF]

Environmental Health and Toxicology, 2017
It is widely accepted that a relatively small proportion of chronic disease can be explained by genetic factors alone. Although information about environmental exposure is important to comprehensively evaluate chronic diseases, this information is not ...
Kyoung-Nam Kim, Yun-Chul Hong
doaj   +1 more source

An integrative analysis of genomic and exposomic data for complex traits and phenotypic prediction

Scientific Reports, 2021
Complementary to the genome, the concept of exposome has been proposed to capture the totality of human environmental exposures. While there has been some recent progress on the construction of the exposome, few tools exist that can integrate the genome ...
Xuan Zhou, S. Hong Lee
doaj   +1 more source

Performance of approaches relying on multidimensional intermediary data to decipher causal relationships between the exposome and health: A simulation study under various causal structures

Environment International, 2021
Challenges in the assessment of the health effects of the exposome, defined as encompassing all environmental exposures from the prenatal period onwards, include a possibly high rate of false positive signals.
Solène Cadiou, Xavier Basagaña, Juan R. Gonzalez, Johanna Lepeule, Martine Vrijheid, Valérie Siroux, Rémy Slama   +6 more
doaj   +1 more source

Exposome-based public health interventions for infectious diseases in urban settings

Environment International, 2021
The COVID-19 pandemic placed public health measures against infectious diseases at the core of global health challenges, especially in cities where more than half of the global population lives.
Xanthi D. Andrianou, Anjoeka Pronk, Karen S. Galea, Rob Stierum, Miranda Loh, Flavia Riccardo, Patrizio Pezzotti, Konstantinos C. Makris   +7 more
doaj   +1 more source

Beyond the single-outcome approach: A comparison of outcome-wide analysis methods for exposome research

Environment International, 2023
Outcome-wide analysis can offer several benefits, including increased power to detect weak signals and the ability to identify exposures with multiple effects on health, which may be good targets for preventive measures.
Augusto Anguita-Ruiz, Ines Amine, Nikos Stratakis, Lea Maitre, Jordi Julvez, Jose Urquiza, Chongliang Luo, Mark Nieuwenhuijsen, Cathrine Thomsen, Regina Grazuleviciene, Barbara Heude, Rosemary McEachan, Marina Vafeiadi, Leda Chatzi, John Wright, Tiffany C. Yang, Rémy Slama, Valérie Siroux, Martine Vrijheid, Xavier Basagaña   +19 more
doaj   +1 more source

Application of two statistical approaches (Bayesian Kernel Machine Regression and Principal Component Regression) to assess breast cancer risk in association to exposure to mixtures of brominated flame retardants and per- and polyfluorinated alkylated substances in the E3N cohort

Environmental Health, 2022
Background Brominated flame retardants (BFR) and per- and polyfluorinated alkylated substances (PFAS) are two groups of substances suspected to act as endocrine disruptors. Such substances could therefore be implicated in the occurrence of breast cancer,
Pauline Frenoy, Vittorio Perduca, German Cano-Sancho, Jean-Philippe Antignac, Gianluca Severi, Francesca Romana Mancini   +5 more
doaj   +1 more source