Results 31 to 40 of about 9,490 (157)

The ageing holobiont: crosstalk between telomere dynamics, oxidative stress and the gut microbiome

Biological Reviews, EarlyView.
ABSTRACT The gut tissue is at the frontline of early onset of ageing. It exhibits high cell turnover rates and rapid telomere shortening, which can have systemic effects on the developing or senescing organism. We conducted a literature review of studies on the crosstalk between telomere length dynamics, telomerase activity, oxidative stress, and gut ...
Michael L. Pepke, Søren B. Hansen, Morten T. Limborg   +2 more
wiley   +1 more source

Characterizing the adult exposome in men and women from the general population: Results from the EHES-LUX study

Environment International, 2023
Throughout life individuals are exposed to a large array of diverse environmental exposures (exposome). Hair analyses can assess chronic exposure to a large number of chemicals with less intra-variability than urine and blood.
Maria Ruiz-Castell, Gwenaëlle Le Coroller, Achilleas Pexaras, Giovana M. Ciprián, Guy Fagherazzi, Torsten Bohn, Léa Maitre, Jordi Sunyer, Brice M.R. Appenzeller   +8 more
doaj   +1 more source

Residence Near Agricultural Crops at Birth and Risk of Adult Testicular Germ Cell Tumors: A French Nationwide Case–Control Study Using Historical Aerial GIS Data

International Journal of Cancer, EarlyView.
As the incidence of testicular germ cell tumors (TGCTs) rises, prenatal exposure to agricultural pesticides may represent an important risk factor. Here, geographic information system‐based measures of farmland proximity at birth were used as a proxy for early‐life pesticide exposure in France, a major pesticide consumer.
Aurélie M. N. Danjou, Astrid Coste, Lény Grassot, Elodie Faure, Carlos Crispim‐Junior, Laure Tougne Rodet, Olivia Pérol, Rémi Béranger, Jeanne Perrin, Barbara Charbotel, Joachim Schüz, Béatrice Fervers, the TESTIS study group, Helen Boyle, Aude Fléchon, Elodie Belladame, Véronique Drouineaud, Céline Chalas, Myriam Virlouvet, Lucile Ferreux, Guillemette Perier, Pauline Peretout, Diane Rivet, Sandrine Rulle, Florence Eustache, Nathalie Sermondade, Marine Durand, Rachel Levy, Isabelle Berthaut, Jacqueline Saias‐Magnan, Catherine Metzler‐Guillemain, Carole Daoud‐Deveze, Louis Bujan, Myriam Daudin, Florence Brugnon, Valérie Bruhat, Cyril Bouche, Isabelle Kocsinski, Marius Teletin, Françoise Schmitt, Nathalie Guyomard, Aline Papaxanthos, Volcy Soula, Sandrine Giscard d’Estaing, Pascale Dehee, Delphine Yalcinkaya, Céline Bouillon, Cynthia Frapsauce, Anne Viallon, Bérengère Ducrocq, Marie‐Ange Clarotti, Ethel Szerman, Amélie Ancelle, Oxana Blagosklonov, Séverine Bey, Célia Ravel, Ségolène Veau, Agnès Letremy, Patricia Fauque, Julie Barberet, Stéphanie Lattes, Emmanuelle Thibault, Catherine Diligent, Christel Hersant, Vanessa Loup‐Cabaniols, Anna Gala, Sylvianne Hennebicq, Julien Bessonnat, Marie‐Claude Blocquaux, Brigitte Dananché, Johan Spinosi, Matthieu Dubuis, Charlotte Carretero, Etienne Durand, Bénédicte Thomas, Rémi Ratajczak   +75 more
wiley   +1 more source

High‐Throughput Geocoding to Assess Short‐Term Air Pollution in Correlation With Mortality in a French Cancer Patient Cohort

International Journal of Cancer, EarlyView.
Although chronic air pollution exposure is linked to lung cancer mortality, the short‐term effects of fluctuating air quality on overall cancer mortality remain uncertain. Here, the authors applied geomatics and machine‐learning models to retrospectively examine possible associations between 31‐day pollution exposure and mortality in a French cancer ...
Loice Pokam, Joséphine Bocquet, Nadia Hégarat, Julie Perlbarg‐Samson, Thomas Balezeau, Maud Milder, Bastien Rance, Hector Countouris, Julien Guerin, Flavien Gilles, Jean Gaudart, Nicolas Girard, Clémence Basse   +12 more
wiley   +1 more source

The human exposome unraveling the impact of environment on health: promise or reality?

Revista de Saúde Pública, 2019
Considering the innovative nature of the approach to human exposome, we present the state of the art of studies on exposome, and discuss current challenges and perspectives in this area.
Kelly Polido Kaneshiro Olympio, Fernanda Junqueira Salles, Ana Paula Sacone da Silva Ferreira, Elizeu Chiodi Pereira, Allan Santos de Oliveira, Isabelle Nogueira Leroux, Flávia Bosquê Alves Vieira   +6 more
doaj   +1 more source

From prediction to actionable mechanisms: Explainable multi‑omics AI for farm‑to‑fork postharvest preservation

iMeta, EarlyView.
Graphical overview of explainable artificial intelligence (XAI) for farm‐to‐fork postharvest preservation. Postharvest deterioration accumulates across orchard, packhouse, refrigerated transportation, warehouse, and distribution stages under fluctuating temperature, humidity, atmosphere, and mechanical stress.
Peihua Ma, Xiaoxue Jia, Bei Fan, Boqiang Li, Tao Lin, Jiping Sheng, Cheng‐I Wei, Yingjian Lu, Yizhou Ma, Lin Chen, Songtao Jiu, Fengzhong Wang   +11 more
wiley   +1 more source

Association of cumulative early medical events and neurodevelopmental conditions through a common latent factor—A population‐based twin study

JCPP Advances, EarlyView.
Abstract Background The cumulative effect of early medical events has been shown to be associated with autism. It is unclear whether this effect is specific to autism or if it is associated to other neurodevelopmental conditions (NDCs) as well. Methods We established a registry‐linked population‐based twin cohort of 10,254 pairs within the child and ...
Torkel Carlsson, Henrik Larsson, Sebastian Lundström, Sven Bölte, Mark J. Taylor   +4 more
wiley   +1 more source

Evaluating the combined toxicity of Penicillium mycotoxins in absorption, metabolism, and excretion systems

Journal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND Penicillium mycotoxins, including ochratoxin A (OTA), citrinin (CIT), and cyclopiazonic acid (CPZ), frequently co‐occur in food commodities, contributing to chronic low‐level dietary exposure. However, current risk assessments often consider these toxins individually, overlooking potential interaction effects.
Carolina Sousa Monteiro, Eugénia Pinto, Miguel A Faria, Sara C Cunha   +3 more
wiley   +1 more source

Redox biology: Interface of the exposome with the proteome, epigenome and genome

Redox Biology, 2014
The exposome is the cumulative measure of environmental influences and associated biological responses throughout lifespan, including exposures from the environment, diet, behavior and endogenous processes. Much of the direct interaction of an individual′
Young-Mi Go, Dean P. Jones
doaj   +1 more source

Startups Driving Artificial Intelligence Into Clinical Dermatology

JEADV Clinical Practice, EarlyView.
ABSTRACT Artificial intelligence (AI) is rapidly transitioning from innovation to routine clinical application in dermatology. This review examines how AI‐enabled technologies are being developed and integrated across diverse clinical purposes and workflows.
Dominique Du Crest, Benjamin Miguel Monteagudo, Stanislas Vandier, Mullarkey Dan, Svedenhag Per, Jon Friis, Monisha Madhumita, Lilit Garibyan, Tu‐Anh Duong, Merete Haedersdal, Vinzent Kevin Ortner   +10 more
wiley   +1 more source