Results 21 to 30 of about 17,412 (233)

The endogenous exposome [PDF]

open access: yesDNA Repair, 2014
The concept of the Exposome, is a compilation of diseases and one’s lifetime exposure to chemicals, whether the exposure comes from environmental, dietary, or occupational exposures; or endogenous chemicals that are formed from normal metabolism, inflammation, oxidative stress, lipid peroxidation, infections, and other natural metabolic processes such ...
Nakamura, Jun   +9 more
openaire   +4 more sources

The exposome in practice: Design of the EXPOsOMICS project

open access: yesInternational Journal of Hygiene and Environmental Health, 2017
EXPOsOMICS is a European Union funded project that aims to develop a novel approach to the assessment of exposure to high priority environmental pollutants, by characterizing the external and the internal components of the exposome. It focuses on air and water contaminants during critical periods of life. To this end, the project centres on 1) exposure
Vineis, P   +14 more
openaire   +8 more sources

The role of inflammation in age-related disease. [PDF]

open access: yes, 2013
The National Institutes of Health (NIH) Geroscience Interest Group (GSIG) sponsored workshop, The Role of Inflammation inAge-Related Disease, was held September 6th-7th, 2012 in Bethesda, MD.
Augustine, Alison Deckhut   +9 more
core   +2 more sources

Chemical safety and the exposome

open access: yesEmerging Contaminants, 2023
Air pollution and rapid chemical intensification are major threats to the environment and human health. Today, we have produced over 350,000 chemicals, and current testing strategies do not meet the demands. Therefore, it is important to develop new approach methodologies (NAMs) that can help fill current information gaps.
openaire   +4 more sources

Exposome approach for identifying modifiable factors for the prevention of colorectal cancer

open access: yesScientific Reports, 2022
Previous studies have shown certain exposure factors (such as lifestyle and metabolism) are associated with colorectal cancer (CRC) events. However, the application of the exposome theoretical frame and the extent to which the exposome domain can ...
Nanqian Chen   +3 more
doaj   +1 more source

Protein Adductomics: Methodologies for Untargeted Screening of Adducts to Serum Albumin and Hemoglobin in Human Blood Samples. [PDF]

open access: yes, 2019
The reaction products of electrophiles in vivo can be measured as adducts to the abundant proteins, hemoglobin (Hb), and human serum albumin (HSA), in human blood samples.
Carlsson, Henrik   +2 more
core   +2 more sources

Environmental risk factors and their footprints in vivo – a proposal for the classification of oxidative stress biomarkers [PDF]

open access: yes, 2020
Environmental agents, including socioeconomic condition, and host factors can act as causal agents and risk factors in disease. We use biomarkers and sociomarkers to study causal factors, such as overproduction of reactive oxygen species (ROS) which ...
Ghezzi, Pietro
core   +1 more source

EXPOsOMICS: final policy workshop and stakeholder consultation

open access: yesBMC Public Health, 2018
The final meeting of the EXPOsOMICS project “Final Policy Workshop and Stakeholder Consultation” took place 28–29 March 2017 to present the main results of the project and discuss their implications both for future research and for regulatory and policy ...
Michelle C. Turner   +23 more
doaj   +1 more source

Recent Trends in Metabolomics by NMR Spectroscopy

open access: yesAngewandte Chemie, EarlyView.
AI tools were applied to analyze more than 5 000 publications indexed in Scopus (2018–2025), identifying key trends and research directions in NMR‐based metabolomics. The artificial intelligence‐assisted workflow classified papers into six main fields of application, human health, food and nutrition, veterinary science, plants, environment, and ...
Giorgio Di Paco   +6 more
wiley   +2 more sources

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