Results 21 to 30 of about 9,490 (157)

EXPOsOMICS: final policy workshop and stakeholder consultation

BMC Public Health, 2018
The final meeting of the EXPOsOMICS project “Final Policy Workshop and Stakeholder Consultation” took place 28–29 March 2017 to present the main results of the project and discuss their implications both for future research and for regulatory and policy ...
Michelle C. Turner, Paolo Vineis, Eduardo Seleiro, Michaela Dijmarescu, David Balshaw, Roberto Bertollini, Marc Chadeau-Hyam, Timothy Gant, John Gulliver, Ayoung Jeong, Soterios Kyrtopoulos, Marco Martuzzi, Gary W. Miller, Timothy Nawrot, Mark Nieuwenhuijsen, David H. Phillips, Nicole Probst-Hensch, Jonathan Samet, Roel Vermeulen, Jelle Vlaanderen, Martine Vrijheid, Christopher Wild, Manolis Kogevinas, on behalf of the EXPOsOMICS Consortium   +23 more
doaj   +1 more source

The human microbial exposome: expanding the Exposome-Explorer database with gut microbial metabolites

Scientific Reports, 2023
Metabolites produced by the gut microbiota play an important role in the cross-talk with the human host. Many microbial metabolites are biologically active and can pass the gut barrier and make it into the systemic circulation, where they form the gut ...
Vanessa Neveu, Geneviève Nicolas, Adam Amara, Reza M. Salek, Augustin Scalbert   +4 more
doaj   +1 more source

Creating personas for exposome research: the experience from the HEAP project [version 1; peer review: 2 approved]

Open Research Europe, 2023
The exposome is a complex scientific field that has enjoyed consistent growth over the last two decades, defined as the composite of every exposure to which an individual is subjected from conception to death.
Heather Coombs, Joakim Dillner, Heimo Müller, Tracy Wootton, Anouk Berger, Zisis Kozlakidis   +5 more
doaj   +1 more source

Manual Friction with Ethyl Alcohol at 70% (w/v) to Disinfect Three-Way Stopcocks

Hygiene, 2023
The disinfection procedures aim to reduce the microbial load, but there are doubts about the risks of contamination spreading into the lumens of devices, such as three-way stopcocks (3-WS).
Gisele Tais Roldão de Souza, Rachel Maciel Monteiro, Lucas Lazarini Bim, Felipe Lazarini Bim, Tatiana Areas da Cruz, Adriano Menis Ferreira, Paula Regina de Souza Hermann, Denise de Andrade, Evandro Watanabe   +8 more
doaj   +1 more source

Modelling socioeconomic position as a driver of the exposome in the first 18 months of life of the NINFEA birth cohort children

Environment International, 2023
Background: The exposome drivers are less studied than its consequences but may be crucial in identifying population subgroups with unfavourable exposures.
Chiara Moccia, Costanza Pizzi, Giovenale Moirano, Maja Popovic, Daniela Zugna, Antonio d'Errico, Elena Isaevska, Serena Fossati, Mark J. Nieuwenhuijsen, Piero Fariselli, Tiziana Sanavia, Lorenzo Richiardi, Milena Maule   +12 more
doaj   +1 more source

An Edible Biohybrid Platform Accomplishes In Situ Fenton‐Mediated Enteral Nanoplastics Aging and Excretion

Advanced Science, EarlyView.
An edible biohybrid platform triggers nanoplastics (NPs) aging and agglomeration by in situ generating hydroxyl radicals within the intestine. The enlarged NPs are unable to penetrate the intestine and are subsequently excreted. Simultaneously, probiotic biofilms reinforce the intestinal barrier.
Su Zhou, Anran Yan, Haowei Guo, Ping Chen, Qiang Chu   +4 more
wiley   +1 more source

From the exposome to mechanistic understanding of chemical-induced adverse effects

Environment International, 2017
The exposome encompasses an individual's exposure to exogenous chemicals, as well as endogenous chemicals that are produced or altered in response to external stressors. While the exposome concept has been established for human health, its principles can
Beate I. Escher, Jörg Hackermüller, Tobias Polte, Stefan Scholz, Achim Aigner, Rolf Altenburger, Alexander Böhme, Stephanie K. Bopp, Werner Brack, Wibke Busch, Marc Chadeau-Hyam, Adrian Covaci, Adolf Eisenträger, James J. Galligan, Natalia Garcia-Reyero, Thomas Hartung, Michaela Hein, Gunda Herberth, Annika Jahnke, Jos Kleinjans, Nils Klüver, Martin Krauss, Marja Lamoree, Irina Lehmann, Till Luckenbach, Gary W. Miller, Andrea Müller, David H. Phillips, Thorsten Reemtsma, Ulrike Rolle-Kampczyk, Gerrit Schüürmann, Benno Schwikowski, Yu-Mei Tan, Saskia Trump, Susanne Walter-Rohde, John F. Wambaugh   +35 more
doaj   +1 more source

Positive association between dietary exposure to polybrominated diphenyl ethers and breast cancer risk in the French E3N cohort: The role of vegetable oil consumption

Environment International, 2022
Exposure to endocrine-disrupting chemicals, like Polybrominated diphenyl ethers (PBDEs), is suspected of playing a role in the occurrence of breast cancer.
Pauline Frenoy, Chloé Marques, Thibault Fiolet, German Cano-Sancho, Gianluca Severi, Francesca Romana Mancini   +5 more
doaj   +1 more source

Microplastics‐Induced Gut Microbiota Dysbiosis Accelerates Alzheimer's‐Like Pathology and Cognitive Decline via the Gut–Brain Axis

Advanced Science, EarlyView.
Microplastics (MPs) breach the gut‐brain axis by triggering taurine‐depleting microbiota dysbiosis that accelerates Alzheimer‐like pathology in 5XFAD mice. Taurine supplementation normalizes autophagy, microglial quiescence, and cognition, and plasma taurine inversely tracks cognitive decline in ADNI participants, revealing a readily translatable ...
Zifeng Wu, Jiarong Yang, Miaoxuan Zhang, Yi Li, Zhuling Tu, Ji Wang, Jin‐Tai Yu, Kun Guo, Rongcan Luo   +8 more
wiley   +1 more source

Perspective on using non-human primates in Exposome research

Ecotoxicology and Environmental Safety
The physiological and pathological changes in the human body caused by environmental pressures are collectively referred to as the Exposome. Human society is facing escalating environmental pollution, leading to a rising prevalence of associated diseases,
Qiu Tu, Gaojing Liu, Xiuyun Liu, Jiao Zhang, Wenxian Xiao, Longbao Lv, Bo Zhao   +6 more
doaj   +1 more source