Results 81 to 90 of about 6,567,287 (293)

Can EGFR-TKIs be used in first line treatment for advanced non-small cell lung cancer based on selection according to clinical factors ? -- A literature-based meta-analysis

Journal of Hematology & Oncology, 2012
Background In the first line treatment of non-small cell lung cancer (NSCLC), several clinical trials have shown that not all NSCLC patients can benefit from treatment with tyrosine kinase inhibitors (TKIs) than receiving chemotherapy.
Xu Chongrui, Zhou Qing, Wu Yi-long
doaj   +1 more source

Chemical characterization of marijuana blunt smoke by non-targeted chemical analysis

Inhalation Toxicology, 2020
Background: Marijuana blunts, which are tobacco cigar wrappers filled with marijuana, are commonly smoked in the US as a means of cannabis use. The use of marijuana blunts presents toxicity concerns because the smoke contains both marijuana-related and tobacco-related chemicals. Thus, it is important to understand the chemical composition of mainstream
Theodore P. Klupinski, Erich D. Strozier, Stephanie D. Makselan, Stephanie S. Buehler, Erica N. Peters, Eric A. Lucas, Jerry S. Casbohm, David A. Friedenberg, Andrew J. Landgraf, Aaron J. Frank, Vladimir B. Mikheev, Alexander Ivanov   +11 more
openaire   +2 more sources

Spatial Discrimination Limit Analysis of Macrophage Phagocytosis Between Target Antigens and Non-Target Objects Using Microcapillary Manipulation Assay

Micromachines
During phagocytosis, the FcGR–IgG bond is thought to be necessary to promote cell-membrane extension as the zipper mechanism. However, does this zipper mechanism provide a spatial antigen discrimination capability that allows macrophages to selectively ...
Maiha Ando, Dan Horonushi, Haruka Yuki, Shinya Kato, Amane Yoshida, Kenji Yasuda   +5 more
doaj   +1 more source

Analysis of Langevin Monte Carlo via convex optimization

, 2018
In this paper, we provide new insights on the Unadjusted Langevin Algorithm. We show that this method can be formulated as a first order optimization algorithm of an objective functional defined on the Wasserstein space of order $2$.
Durmus, Alain, Majewski, Szymon, Miasojedow, Błażej   +2 more
core  

‘They Need to Hear You Say It’: Healthcare Professionals’ Perspectives on Barriers and Enablers to End‐of‐Life Discussions With Adolescents and Young Adults With Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT End‐of‐life conversations with adolescents and young adults (AYAs) with cancer rarely occur without the guidance of healthcare professionals. As a part of the ‘Difficult Discussions’ study, focused on palliative care and advance care planning discussions with AYAs with cancer, we investigated the factors that healthcare professionals identify ...
Justine Lee, Holly Evans, Claire E. Wakefield, Antoinette Anazodo, Richard J. Cohn, Brittany C. McGill, Elizabeth A. Lobb, Lori Wiener, Madeleine L. Juhrmann, Ursula M. Sansom‐Daly   +9 more
wiley   +1 more source

Cluster-driven non-uniform characteristic analysis of underwater target acoustic scattering field

Frontiers in Physics
Underwater small targets typically exhibit non-centrosymmetric geometries, resulting in a highly spatially inhomogeneous acoustic scattering field under active sonar detection.
Tianyang Xu, Hongjian Jia, Jixing Qin
doaj   +1 more source

Feasibility and Safety of High‐Dose Proton Re‐Irradiation in Recurrent Pediatric Central Nervous System Tumors: A Single‐Institution Retrospective Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Pediatric central nervous system (CNS) tumors often recur despite multimodality therapy. Although re‐irradiation (re‐RT) has historically been limited by concerns for severe late toxicities, modern techniques have renewed interest in this approach. Proton therapy provides dosimetric advantages that may enable curative re‐treatment with
Jin‐Ho Song, Jonathan Baron, Carlos Chavez Perez, Sidharth Ramesh, Jane Minturn, Kavita A. Desai, Amish C. Shah, Jean M. Belasco, Kristina A. Cole, Michael J. Fisher, Phillip B. Storm, Peter M. Madsen, Goldie Kurtz, Robert A. Lustig, Christine Hill‐Kayser, Michael J. LaRiviere   +15 more
wiley   +1 more source

Passive Target Motion Analysis With Own‐Ship Location Uncertainty in the Presence of Non‐Gaussian Sensor Noise

IET Radar, Sonar & Navigation
Passive target motion analysis (TMA) is traditionally performed using angle‐only measurements, which requires the own‐ship to execute a manoeuvre to make the tracking system observable. These manoeuvres are burdensome for the naval community. In contrast,
Rohit Kumar Singh, Shreya Das, Shovan Bhaumik   +2 more
doaj   +1 more source

Analysis of Pulsed Laser Target Echo Characteristics in Non-Uniform Smoke Environments

Photonics
This study establishes a mathematical model for analyzing pulsed laser target echo signals in non-uniform smoke environments, thereby enabling evaluations of the target echo characteristics of laser detection systems under various smoke conditions.
Chenyoushi Xu, Ruihua Zhang, Zhen Zheng, Bingting Zha, Weiping Cao, He Zhang   +5 more
doaj   +1 more source

Feasibility and Preliminary Efficacy of Integrative Neuromuscular Training for Childhood Cancer Survivors: A Pilot Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Survivors of childhood acute lymphoblastic leukemia (ALL) often exhibit early deficits in muscle and movement competence, which can compromise long‐term health. Integrative neuromuscular training (INT), a multifaceted approach combining fundamental movement activities with strength exercises, may help address these deficits during ...
Anna Maria Markarian, Robert U. Newton, Dennis R. Taaffe, Nicholas G. Gottardo, Santosh Valvi, Carolyn J. Peddle‐McIntyre, Jodie Cochrane Wilkie, Daniel A. Galvão   +7 more
wiley   +1 more source