Results 71 to 80 of about 1,210,639 (292)

Behavioural types for non-uniform memory accesses

open access: yes, 2016
Concurrent programs executing on NUMA architectures consist of concurrent entities (e.g. threads, actors) and data placed on different nodes. Execution of these concurrent entities often reads or updates states from remote nodes.
Drossopoulou, Sophia, Franco, Juliana
core   +2 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Injection Of air control of propeller performance

open access: yesEngineering Applications of Computational Fluid Mechanics
With the rise of bubble lubrication technology in transport ships, the interaction between propellers and bubble flow has become increasingly important. On the basis of solving the Reynolds averaged equation and the volume fraction equation, a numerical ...
Zhibo Wang, Jinjing Gu
doaj   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Selfish Network Creation with Non-Uniform Edge Cost

open access: yes, 2017
Network creation games investigate complex networks from a game-theoretic point of view. Based on the original model by Fabrikant et al. [PODC'03] many variants have been introduced.
A Cord-Landwehr   +17 more
core   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Attention Network for Non-Uniform Deblurring

open access: yesIEEE Access, 2020
Recently, image deblurring task is valuable and challenging in computer vision. However, existing learning-based methods can not produce satisfactory results, such as lacking of salient structures and fine details. In this paper, we propose a solution to
Qing Qi, Jichang Guo, Weipei Jin
doaj   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Color Constancy for Uniform and Non-Uniform Illuminant Using Image Texture

open access: yesIEEE Access, 2019
Color constancy is the capability to observe the true color of a scene from its image regardless of the scene’s illuminant. It is a significant part of the digital image processing pipeline and is utilized when the true color of an object is ...
Md Akmol Hussain   +2 more
doaj   +1 more source

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