Results 81 to 90 of about 1,150,684 (289)

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Cost Effective Offline Reconfiguration for Large-Scale Non-Uniformly Aging Photovoltaic Arrays Efficiency Enhancement

open access: yesIEEE Access, 2020
In the past decades, a huge number of large-scale photovoltaic (PV) plants have been constructed all around the world. However, the capital and operational costs can be high, which limits their widespread applications.
Zuyu Wu   +4 more
doaj   +1 more source

On $\ell$-torsion in class groups of number fields

open access: yes, 2017
For each integer $\ell \geq 1$, we prove an unconditional upper bound on the size of the $\ell$-torsion subgroup of the class group, which holds for all but a zero-density set of field extensions of $\mathbb{Q}$ of degree $d$, for any fixed $d \in \{2,3 ...
Ellenberg, Jordan   +2 more
core   +1 more source

Non-uniform stability for bounded semi-groups on Banach spaces

open access: yesJournal of Evolution Equations, 2008
Let S(t) be a bounded strongly continuous semi-group on a Banach space B and – A be its generator. We say that S(t) is semi-uniformly stable when S(t)(A + 1)−1 tends to 0 in operator norm. This notion of asymptotic stability is stronger than pointwise stability, but strictly weaker than uniform stability, and generalizes the known logarithmic ...
Batty, C, Duyckaerts, T
openaire   +2 more sources

NKCC1: A key regulator of glioblastoma progression

open access: yesMolecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen   +5 more
wiley   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

open access: yesFEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini   +2 more
wiley   +1 more source

Uniform bounds for solutions to elliptic problems on simply connected planar domains

open access: yes, 2018
We consider the singular Liouville equation and the Henon-Lane-Emden problem on simply connected planar domains. We show that any solution to each problem must satisfy a uniform bound on the mass. The same results applies to some systems and more general
Battaglia, Luca
core   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

Constrained Multiple Model Particle Filtering for Bearings-Only Maneuvering Target Tracking

open access: yesIEEE Access, 2018
This paper presents an effective constrained multiple model particle filtering (CMMPF) for bearings-only maneuvering target tracking. In the proposed algorithm, the process of target tracking is factorized into two sub-problems: 1) motion model ...
Hongwei Zhang, Liangqun Li, Weixin Xie
doaj   +1 more source

NURBS-based kinematic limit analysis of FRP-reinforced masonry walls with out-of-plane loading

open access: yesFracture and Structural Integrity, 2020
A three-dimensional (3D) general upper-bound limit analysis procedure for the determination of the collapse load of out-of-plane loaded masonry walls with Fiber Reinforced Polymer (FRP) reinforcement strips is presented.
Andrea Chiozzi   +3 more
doaj   +1 more source

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