Results 41 to 50 of about 17,181,475 (289)
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Effect of non-uniform magnetic field on crystal growth by floating-zone method in microgravity
, 2001 The magnetic damping effect of the non-uniform magnetic field on the floating-zone crystal growth process in microgravity is studied by numerical simulation. The results show that the non-uniform magnetic field with designed configuration can effectively
胡文瑞 +2 more
core +1 more source
Chemosensors, 2023 At the moment, manipulation of liquid microdroplets is required in various microfluidic and lab-on-a-chip devices, as well as advanced sensors. The platforms used for these purposes should provide the possibility of controlled selective movement and ...
Georgii Pavliuk +2 more
doaj +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
AIP Advances, 2016 Molecular dynamics simulations are performed to investigate the nano-droplets coalescence process in a non-uniform electric field. Coalescence of droplets driven by dielectrophoresis (DEP) could be observed clearly in a strong electric field.
Qicheng Chen +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Magnetic field induced orientational transitions in liquid crystals doped with carbon nanotubes
Beilstein Journal of Nanotechnology, 2017 We propose a continuum theory of orientational phase transitions induced by an external magnetic field in a suspension of carbon nanotubes in a nematic liquid crystal.
Danil A. Petrov +2 more
doaj +1 more source
Energies, 2020 This paper describes a correlation of partial discharge phase-resolved patterns with an optical imaging performed in a non-uniform electric field configuration.
Marek Florkowski +3 more
doaj +1 more source