Results 41 to 50 of about 411,672 (266)

Microscopic mechanism on coalescence of the nano-droplets in present non-uniform electric field by molecular dynamics simulations

open access: yesAIP Advances, 2016
Molecular dynamics simulations are performed to investigate the nano-droplets coalescence process in a non-uniform electric field. Coalescence of droplets driven by dielectrophoresis (DEP) could be observed clearly in a strong electric field.
Qicheng Chen   +3 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Magnetic field induced orientational transitions in liquid crystals doped with carbon nanotubes

open access: yesBeilstein Journal of Nanotechnology, 2017
We propose a continuum theory of orientational phase transitions induced by an external magnetic field in a suspension of carbon nanotubes in a nematic liquid crystal.
Danil A. Petrov   +2 more
doaj   +1 more source

Partial Discharge Imaging Correlated with Phase-Resolved Patterns in Non-Uniform Electric Fields with Various Dielectric Barrier Materials

open access: yesEnergies, 2020
This paper describes a correlation of partial discharge phase-resolved patterns with an optical imaging performed in a non-uniform electric field configuration.
Marek Florkowski   +3 more
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Non-uniform electric field-induced yeast cell electrokinetic behavior

open access: yesIngeniería e Investigación, 2008
Common dielectrophoresis (c-DEP, i.e. neutral matter motion induced by non-uniform electric fields) has become a basic pheno-menon of biochips intended for medical, biological and chemical assays, especially when they imply bioparticle handling.
Flavio Humberto Fernández Morales   +2 more
doaj  

The Future of Pediatric Hematology‐Oncology Fellowship Training: Reflections on the American Board of Pediatrics Training Model

open access: yes
Pediatric Blood &Cancer, EarlyView.
Scott C. Borinstein   +11 more
wiley   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

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