Results 51 to 60 of about 17,181,475 (289)
CEACAM1 participation in breast cancer progression
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Approximate Methods for Calculating a Non-Uniform Travelling Field
Abstract The approximation methods for calculating the non-uniform travelling field, which is formed by a series of parallel cylindrical electrodes located at equal intervals on a plane and applied with balanced three-phase voltage, are presented. The substitute-charge method using line-charges located inside the cylinders as their substitute-charges
Masuda, Sen-ichi, Kamimura, Tsutomu
openaire +2 more sources
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley +1 more source
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
Non-uniform electric field-induced yeast cell electrokinetic behavior
Common dielectrophoresis (c-DEP, i.e. neutral matter motion induced by non-uniform electric fields) has become a basic pheno-menon of biochips intended for medical, biological and chemical assays, especially when they imply bioparticle handling.
Flavio Humberto Fernández Morales +2 more
doaj
Visual Perception in Non-uniform Fields
Adaptation for uniform fields and for non-uniform fields is compared. Experimentally, the luminance difference thresholds for the Foveal Adaptation Luminance (Lf), the Background Luminance (Lb) and the Equivalent Veiling Luminance (Leq) are separately investigated.
openaire +2 more sources
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
THE PROCESS OF HEAT TRANSFER IN TWO-LAYERED CYLINDRICAL BODY
Determination of thermal regimes of composite cylindrical bodies by analytical methods leads to the appearance of complex characteristic equations, the solution of which is the determination of eigenvalues.
U. V. Vidin, R. V. Kazakov, V. S. Zlobin
doaj +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source

