Results 51 to 60 of about 17,181,475 (289)

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Approximate Methods for Calculating a Non-Uniform Travelling Field

open access: yesIEEJ Transactions on Fundamentals and Materials, 1975
Abstract The approximation methods for calculating the non-uniform travelling field, which is formed by a series of parallel cylindrical electrodes located at equal intervals on a plane and applied with balanced three-phase voltage, are presented. The substitute-charge method using line-charges located inside the cylinders as their substitute-charges
Masuda, Sen-ichi, Kamimura, Tsutomu
openaire   +2 more sources

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

open access: yesMolecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

open access: yesMolecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim   +7 more
wiley   +1 more source

Non-uniform electric field-induced yeast cell electrokinetic behavior

open access: yesIngeniería e Investigación, 2008
Common dielectrophoresis (c-DEP, i.e. neutral matter motion induced by non-uniform electric fields) has become a basic pheno-menon of biochips intended for medical, biological and chemical assays, especially when they imply bioparticle handling.
Flavio Humberto Fernández Morales   +2 more
doaj  

Visual Perception in Non-uniform Fields

open access: yesJournal of Light & Visual Environment, 1992
Adaptation for uniform fields and for non-uniform fields is compared. Experimentally, the luminance difference thresholds for the Foveal Adaptation Luminance (Lf), the Background Luminance (Lb) and the Equivalent Veiling Luminance (Leq) are separately investigated.
openaire   +2 more sources

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

THE PROCESS OF HEAT TRANSFER IN TWO-LAYERED CYLINDRICAL BODY

open access: yesИзвестия высших учебных заведений: Проблемы энергетики, 2019
Determination of thermal regimes of composite cylindrical bodies by analytical methods leads to the appearance of complex characteristic equations, the solution of which is the determination of eigenvalues.
U. V. Vidin, R. V. Kazakov, V. S. Zlobin
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

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