Results 131 to 140 of about 505,868 (261)

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Impact of scaphoid non-union characteristics on healing outcomes. [PDF]

JPRAS Open
Labèr R, Lautenbach G, Schweizer A.
europepmc   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Non-union after bisphosphonate-associated atypical femoral fractures: a review of the current literature. [PDF]

Eur J Orthop Surg Traumatol
Dowling J, Marsh S, O'Grady J.
europepmc   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Near-Infrared Fluorescence Imaging for Intraoperative Perfusion Assessment of the Bone During Elective Non-union Surgery: A Feasibility Study. [PDF]

JB JS Open Access
Koning S, Boldewijn DF, Dalmeijer SWR, Zweedijk BE, Kruiswijk MW, Peul RC, van der Aa LE, Planting I, Tange FP, Hoven van den P, Hilling DE, Keereweer S, Vahrmeijer AL, Verhofstad MHJ, Verhofstad MHJ, Hamming JF, Schipper IB, Wijffels MME, van der Vorst JR.   +18 more
europepmc   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Circulating CD38⁺ regulatory T cells are decreased in bone fracture non-union with chronic subclinical infection. [PDF]

Sci Rep
Fehrenbach P, Siverino C, Trenkwalder K, Erichsen S, Hackl S, Weisemann F, Muthukrishnan G, Riool M, Akdis CA, Garcia-Vallejo JJ, Zaat SAJ, de Jong EC, Moriarty TF.   +12 more
europepmc   +1 more source

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

Aging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss, Alexis C. Wardell, Allison M. Deal, Kirsten A. Nyrop, Allison Ross, Yara G. Abdou, Jeffrey D. Aldrich, Lisa A. Cary, E. Claire Dees, Katherine E. Reeder‐Hayes, Emily M. Ray, Natalia Mitin, Denis Tsygankov   +12 more
wiley   +1 more source

Clavicle Fracture Non-Union in a 3-Year-Old Child: A Case Report and Literature Review. [PDF]

J Orthop Case Rep
Kumar R, Tripathi A, Kumar N, Kumar G.
europepmc   +1 more source