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Transposon Vectors Enable Accelerated Development of Cellular Assay Platforms for the Identification and Characterization of Anti-Viral Small-Molecule Cell-Entry Inhibitors and Neutralizing Antibodies. [PDF]
Pißarreck M +3 more
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Advancing Chikungunya Prevention and Vaccination in Mexico: A Position Paper by the Immunization Committee of the Mexican Association of Pediatric Infectious Diseases. [PDF]
Vázquez-Narváez JA +6 more
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Vector competence of temperate and tropical mosquito species for Babanki virus. [PDF]
Ban M +10 more
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Advances in the application of recombinant herpesvirus-vectored vaccines in animal disease control. [PDF]
Guo J +6 more
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Non-viral vectors for the mediation of RNAi
Bioorganic Chemistry, 2012Though the delivery of siRNA into cells, tissues or organs remains to be a big obstacle for its applications, recently siRNA therapeutics has developed rapidly and already there are clinical trials ongoing or planned. Some non-viral vectors have attracted much more attention and shown the great potential for combating the delivery obstacle.
Shubiao, Zhang +3 more
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Production of Non Viral DNA Vectors
Current Gene Therapy, 2010After some decades of research, development and first clinical approaches to use DNA vectors in gene therapy, cell therapy and DNA vaccination, the requirements for the pharmaceutical manufacturing of gene vectors has improved significantly step by step.
Martin, Schleef +6 more
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Non-viral vectors for gene-based therapy
Nature Reviews Genetics, 2014Gene-based therapy is the intentional modulation of gene expression in specific cells to treat pathological conditions. This modulation is accomplished by introducing exogenous nucleic acids such as DNA, mRNA, small interfering RNA (siRNA), microRNA (miRNA) or antisense oligonucleotides.
Hao, Yin +5 more
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Synthetic Peptides As Non-Viral DNA Vectors
Current Gene Therapy, 2006The use of multiple peptide motifs to provide effective gene delivery holds great promise as an elegant, non-immunogenic approach to gene therapy. The molecular understanding of cell and viral biology provides a strong foundation on which to pursue this objective. Synthetic peptides containing multiple lysines and/or arginines (occasionally ornithines)
Fabre, J W, Collins, L
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