Results 51 to 60 of about 2,695,761 (299)

The Problematic Nature of Using Western Treatments for PTSD in Non-Western Settings and a Discussion of Culturally Sensitive Interventions [PDF]

open access: yes, 2010
In recent years, American clinicians have sought to diagnose and treat individuals with Post-Traumatic Stress Disorder around the world. Despite noble intentions, their faulty assumption that western treatments for trauma are universally applicable is ...
Baldachin, Jenna
core   +2 more sources

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Non-Western International Relations Theory: Myth or Reality?

open access: yesVestnik RUDN. International Relations, 2017
In recent years, Russian and foreign literature increasingly raises the question on national theories of international relations. A special interest is manifested towards non-Western theories of international relations.
Marina Mikhailovna Lebedeva
doaj   +1 more source

Homosexual rights and the non-western world: a postcolonial reading of homosexual rights in international human rights law [PDF]

open access: yes, 1999
This paper examines the calls for the international legal recognition and protection of rights for homosexual men and women. To undertake such an examination, the paper utilises theoretical paradigms from within the field of postcolonial studies. Opening
Obendorf, Simon
core   +1 more source

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

open access: yesMolecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad   +35 more
wiley   +1 more source

Typical Islands, Borrowed Islands: Epistemological and Intellectual Decolonialization in Island Studies

open access: yesIsland Studies Journal, 2023
In the emerging scene of non-western island studies, research done on the sinophone world mainly (but not exclusively) by sinophone scholars has become a conspicuous strand in the literature. Despite the diverse locations in focus, most research tends to
Gang Hong
doaj   +1 more source

Against Marrying a Stranger Marital Matchmaking Technologies in Saudi Arabia

open access: yes, 2017
Websites and applications that match and connect individuals for romantic purposes are commonly used in the Western world. However, there have not been many previous investigations focusing on cultural factors that affect the adoption of similar ...
Abokhodair, Norah   +3 more
core   +1 more source

India as a global security actor [PDF]

open access: yes, 2014
Thanks to sustained economic growth and key investments in military capabilities, India will face growing demands from within and the international community to seek and play a greater role in global security affairs.
Asian Development Bank   +22 more
core   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

open access: yesMolecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone   +11 more
wiley   +1 more source

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