Results 41 to 50 of about 18,791,723 (223)

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Further Reflections on Samuel P. Huntington’s “Clash of Civilization” and Contemporary Global Politics

open access: yesArụmarụka, 2022
When civilizations clash or encounter one another, it is a general expectation that one of them will necessarily influence or even dominate the other. This has been the principal character of the advent of Euro-Western civilizations across regions of the
Damilola Peter Olatade
doaj   +2 more sources

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Non-Western International Relations Theory: Myth or Reality?

open access: yesVestnik RUDN. International Relations, 2017
In recent years, Russian and foreign literature increasingly raises the question on national theories of international relations. A special interest is manifested towards non-Western theories of international relations.
Marina Mikhailovna Lebedeva
doaj   +1 more source

Life-Span Developmental Psychology: Midlife and Later Years in Western and Non-Western Societies [PDF]

open access: yes, 2002
This chapter discusses the basis on which studies have been done on the later years of life in Western and non-Western cultures. It suggests that because Westerners value independence, most research on aging in Western societies has focused on how to ...
Eyetsemitan, Frank, Frank Eyetsemitan
core   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

open access: yesFEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos   +9 more
wiley   +1 more source

Western String Chamber Orchestra, November 14, 1996

open access: yes, 2016
Recorded during a live performance at Dalton Center Recital Hall, Western Michigan University, Kalamazoo, Michigan, November 14, 1996, 8:00 p.m., the 137th concert of the School of Music's 1996-1997 season.Western String Chamber Orchestra, Bruce J ...
Western String Chamber Orchestra
core   +2 more sources

Western String Chamber Orchestra, March 29, 1993

open access: yes, 2016
Recorded during a live performance at Dalton Center Recital Hall, Western Michigan University, Kalamazoo, Michigan, March 29, 1993, 8:00 p.m., the 419th concert of the School of Music’s 1992-1993 season.Western String Chamber Orchestra, Bruce Uchimura ...
Western String Chamber Orchestra
core   +2 more sources

Western Winds, November 3, 1999

open access: yes, 2016
Recorded during a live performance at Dalton Center Recital Hall, Western Michigan University, Kalamazoo, Michigan, November 3, 1999, 8:00 p.m., the 111th concert of the School of Music's 1999-2000 season.1st work transcribed from Rossini's 4th sonata ...
Western Winds
core   +1 more source

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