Results 51 to 60 of about 18,791,723 (223)
Island Studies Journal, 2023 In the emerging scene of non-western island studies, research done on the sinophone world mainly (but not exclusively) by sinophone scholars has become a conspicuous strand in the literature. Despite the diverse locations in focus, most research tends to
Gang Hong
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Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
DNA ligase LigE increases bacterial transformation with damaged extracellular DNA
FEBS Letters, EarlyView.The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan +4 more
wiley +1 more source
Non-Western responses to Russia's war in Ukraine: Learning from Indonesia [PDF]
Journal of Regional Security, 2023 Using Indonesia, one of the leading voices in the so-called Global South, I trace the diverse narratives of non-Western elites on interpreting the war in Ukraine, the relationship between Russia and the "non-Western" world, and the NATO factors. The lack
Dharmaputra Radityo
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Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
, 2016 Recorded during a live performance at Miller Auditorium, Western Michigan University, Kalamazoo, Michigan, October 11, 1998, 3:00 p.m., the 53rd concert of the School of Music's 1998-1999 season.University Symphony Orchestra, Bruce J. Uchimura, conductor.
Western Michigan University Symphony Orchestra
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Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
Modernization theory - and the non-western world [PDF]
, 2004 "In this paper I want to deal with three topics: first, with the development and the ups and downs of modernization theory and its treatment of the non-Western world (I), secondly, with some basic social structure distributions and trends of human development for selected societies, including Islamic countries (II), thirdly, with modernization and ...
openaire +3 more sources
A Revised framework to address TB-HIV co-infection in the Western Pacific Region [PDF]
1. Introduction. -- 2. Background . -- 3. Conceptual framework -- 4. TB-HIV surveillance -- 5. HIV testing in TB patient care settings -- 6. Intensified TB case-finding in HIV care settings. -- 7. Treatment for people with both TB and HIV -- 8.
World Health Organization Regional Office for the Western Pacific.
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