Results 221 to 230 of about 173,203 (312)

Identification and Characterization of Three Novel Biomarkers for Mixed/Cholestatic Drug‐Induced Liver Injury

open access: yesHepatology Research, EarlyView.
Three metabolites, pyroglutamylglycine (pyroGluGly), phenylalanine (Phe), and phenylalanyltryptophan (PheTrp), were identified as candidate DILI biomarkers. The serum concentrations of pyroGluGly, Phe, and PheTrp demonstrated a high differentiating ability in patients with mixed and cholestatic DILI compared with those in patients who recovered from ...
Kosuke Saito   +22 more
wiley   +1 more source

Metabolic Health Phenotypes Among Middle‐ to Older‐Aged Adults Living With and Without Obesity: Relationships With Hepatic Health Indicators

open access: yesHepatology Research, EarlyView.
We examined liver health indicators among obese and nonobese metabolic health phenotypes. In fully adjusted models, higher fatty liver index (FLI) scores and liver enzyme concentrations of gamma‐glutamyl transferase (GGT) and alanine aminotransferase (ALT) were associated with lower likelihood of metabolically healthy obese (MHO) and nonobese (MHNO ...
Grainne Dolan   +3 more
wiley   +1 more source

Epidemiology of Metabolic Dysfunction–Associated Steatotic Liver Disease in South Asian Ethnicities: A Systematic Review and Meta‐Analysis

open access: yesJournal of Gastroenterology and Hepatology, EarlyView.
ABSTRACT Background and Aims People of South Asian ethnicities are at increased risk of metabolic syndrome, but the epidemiology of metabolic dysfunction–associated steatotic liver disease (MASLD) in this population remains poorly understood. This systematic review and meta‐analysis assesses the prevalence, cross‐sectional severity, and clinically ...
Michael James   +4 more
wiley   +1 more source

A novel index including SNPs for the screening of nonalcoholic fatty liver disease among elder Chinese

open access: gold, 2018
Huanhuan Yang   +6 more
openalex   +1 more source

Inflammatory and Immunological Basis of Periodontal Diseases

open access: yesJournal of Periodontal Research, EarlyView.
The periodontal lesion emerges as an evolving immunological battlefield, where host–microbiome interactions, dysregulated immune responses, fragile resolution mechanisms, and inflammophilic dysbiosis converge to shift the balance from homeostasis to unrestrained tissue destruction.
Giacomo Baima   +3 more
wiley   +1 more source

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