Results 231 to 240 of about 94,246 (299)

Chrysin Exhibits Bone‐Protective Effects Through Osteoclastogenesis Inhibition: In Vitro and In Vivo Evaluation in RAW 264.7 Murine Macrophages and Sprague–Dawley Rats

open access: yesMolecular Nutrition &Food Research, Volume 70, Issue 3, 13 February 2026.
The effects of chrysin, a plant‐derived compound, were investigated on osteoclast formation in cell culture and bone health parameters in Sprague–Dawley rats. Chrysin was shown to disrupt key osteoclast signaling pathways and inhibit osteoclast formation. Furthermore, chrysin moderately improved bone health parameters in the rats.
Caitlin Mason   +2 more
wiley   +1 more source

Examining Biomarkers for Dyslipidemia, Diabetes, and NAFLD by CDC's 2022 Extended BMI Percentiles in US Youth Aged 6–17 Years

open access: yesObesity, Volume 34, Issue 2, Page 450-459, February 2026.
ABSTRACT Objective This study examined associations between CDC's 2022 extended BMI percentiles (BMIp) and cardiometabolic biomarkers. Methods Using electronic medical record data, we included patients aged 6–17 years with BMI ≥ 85th percentile who had at least one of the following: total cholesterol, low‐density lipoprotein cholesterol (LDL), high ...
Samantha L. Pierce   +4 more
wiley   +1 more source

Model‐Based Meta‐Analysis of the Relationship Between Pioglitazone and Histological Outcomes in Metabolic Dysfunction‐Associated Steatohepatitis Patients

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 2, February 2026.
ABSTRACT Given the high prevalence of the population who have metabolic dysfunction‐associated steatohepatitis (MASH), interest is growing in MASH‐targeted treatments. However, currently, there has been only one regulatory approved drug for MASH (Rezdiffra).
Quyen Thi Tran   +11 more
wiley   +1 more source

Hevin Promotes Aging‐Related Cardiac Dysfunction via Facilitating Cardiac Inflammation in Male Mice

open access: yesAging Cell, Volume 25, Issue 2, February 2026.
Hevin released by iWAT into circulation stimulates cardiac macrophages through TLR4, inducing their polarization and CCL5 secretion, leading to worsened cardiac dysfunction and subsequent recruitment of additional inflammatory cells for pro‐inflammatory factor release.
Shi‐Yu Huang   +4 more
wiley   +1 more source

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