The Association Between Dietary Acid Load and Non‐Alcoholic Fatty Liver Disease
Based on the findings of this systematic review, higher dietary acid load (assessed by PRAL and NEAP scores) is significantly associated with an increased risk of non‐alcoholic fatty liver disease (NAFLD) in adults. The primary mechanisms underlying this relationship appear to be the induction of insulin resistance, systemic inflammation, and ...
Nadia Homayounfar +3 more
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Association between serum insulin levels and ultrasound-defined nonalcoholic fatty liver disease: A cross-sectional study based on NHANES 2017-2020. [PDF]
Li M, Qiu S, Xiang M.
europepmc +1 more source
Tet regulates lipid metabolism and cell apoptosis to alleviate NAFLD. Integrated network pharmacology, Mendelian randomization, and experimental validation demonstrate that Tet activates the PI3K/AKT/STAT3 signaling axis, suppresses apoptosis, reduces hepatic lipid accumulation, and improves biochemical liver injury markers, supporting its potential as
Peng Sun +11 more
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Multi-omics analysis reveals gut microbiota remodeling and lipid metabolism regulation during the treatment of nonalcoholic fatty liver disease with Yindan Pinggan capsule. [PDF]
Hou J +5 more
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Pachymic acid alleviates non‐alcoholic fatty liver disease via FGF21‐mediated inhibition of the p38 MAPK pathway. Pachymic acid (PAC) exerts anti‐ non‐alcoholic fatty liver disease (NAFLD) effects by promoting FGF21 expression, activating FGF21/FGFR1 signaling, and thereby suppressing p38 MAPK phosphorylation. ABSTRACT Non‐alcoholic fatty liver disease
Lijuan Nie +8 more
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Clinical studies identified 93 obesity‐associated and 24 NAFLD‐associated exosomal miRNAs, with let‐7b and miR‐335‐5p emerging as common nodes. Bioinformatics analysis revealed extensive overlap at the functional level, including 40,410 shared miRNA‐mRNA interactions and 42 common target genes. Several circulating exosomal miRNAs from obese individuals,
Qigui Mo +8 more
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Predictive role of lactate dehydrogenase-to-albumin ratio (LAR) in nonalcoholic fatty liver disease and advanced liver fibrosis. [PDF]
Li G, He T, Geng M, Hong S, Qi F.
europepmc +1 more source
With the development of society and the economy, nonalcoholic fatty liver disease (NAFLD) has become a major chronic disease in contemporary society. Finding a safe, effective, and economical method is essential for the treatment of NAFLD. Puerarin is a unique component of pueraria.
Wei Wang, Xiang Liu
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Influence of an internet-based proactive follow-up management model on the prognosis of nonalcoholic fatty liver disease. [PDF]
Liu SY, Gao GF, Wang XY, Yu J.
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Adverse Events of Saffron (Crocus sativus L.): Systematic Review of Current Evidence
ABSTRACT Background Crocus sativus L., commonly known as saffron, is a widely used spice with a rich history of culinary and medicinal applications. This systematic review aims to compile human data from studies on monopreparations of C. sativus, including stigma powder and other extracts, to evaluate their safety.
Fatemeh Sadat Hasheminasab +3 more
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