Results 21 to 30 of about 5,865,913 (286)
Mitochondrial stress in advanced fibrosis and cirrhosis associated with chronic hepatitis B, chronic hepatitis C, or nonalcoholic steatohepatitis
Hepatology, EarlyView., 2022 Adaptive mitochondrial mechanisms allow mitochondrial resilience and prevent the worsening of fibrosis, while deregulation of these mechanisms promotes the progression from no/minimal‐mild (F0‐F2) fibrosis to advanced fibrosis and cirrhosis (F3‐F4). Abstract Background and Aims
Hepatitis B virus (HBV) infection causes oxidative stress (OS) and alters ...Dimitri Loureiro, Issam Tout, Stéphanie Narguet, Cheikh Mohamed Bed, Morgane Roinard, Ahmad Sleiman, Nathalie Boyer, Nathalie Pons‐Kerjean, Corinne Castelnau, Nathalie Giuly, Dorothy Tonui, Vassili Soumelis, Jamel El Benna, Patrick Soussan, Richard Moreau, Valérie Paradis, Abdellah Mansouri, Tarik Asselah +17 morewiley +1 more sourceAttacking the public health crisis of hepatocellular carcinoma at its roots
Hepatology, EarlyView., 2022 Abstract
As the third most common cause of cancer‐related death worldwide with significant mortality rates in the United States, hepatocellular carcinoma has strong association with cirrhosis and chronic hepatitis B virus (HBV) with a growing at‐risk population from the rise in chronic liver disease from alcohol use and nonalcoholic fatty liver disease.Hannah M. Lee, Steven D. Lidofsky, Tamar H. Taddei, Lisa J. Townshend‐Bulson +3 morewiley +1 more sourceGlucokinase links Kruppel-like factor 6 to the regulation of hepatic insulin sensitivity in nonalcoholic fatty liver disease [PDF]
, 2011 The polymorphism, KLF6-IVS1-27A, in the Krüppel-like factor 6 (KLF6) transcription factor gene enhances its splicing into antagonistic isoforms and is associated with delayed histological progression of nonalcoholic fatty liver disease (NAFLD).Gastaldelli, Amalia, Lee, Y., Isabel Fiel, Elisabetta Bugianesi, Miele, L., Lee, U., Bugianesi, E., Emma Buzzigoli, Andrea Mari, Pascoe, L., Mark Walker, Christopher P. Day, Burt, Alastair D., Walker, M., Bechmann, L., Hui, Kei Y, Fiel, I., Buzzigoli, E., Bechmann, Lars P., Miele, Luca, Fiel, Isabel., Luca Miele, Mari, Andrea, Patman, G., Ursula Muñoz, Day, Christopher P., Vetter, Diana., Burt, A., Lee, Young-Min., Munoz, Ursula., Hannivoort, Rebekka A., Alastair D. Burt, Amalia Gastaldelli, Walker, Mark., Agius, Loranne, Mari, A., Agius, Loranne., et al., Buzzigoli, Emma, Walker, Mark, Loranne Agius, Scott L. Friedman, Lee, Young-Min, Pascoe, Laura., Miele, Luca., Munoz, Ursula, Hui, K., Day, C., Laura Pascoe, Pascoe, Laura, Gastaldelli, Amalia., Fiel, Isabel, Ursula E. Lee, Gillian L. Patman, Munoz, U., Kei Y. Hui, Agius, L., Mari, Andrea., Vetter, D., Demetrio Ciociaro, Ciociaro, D., Buzzigoli, Emma., Lars P. Bechmann, Helen L. Reeves, Patman, Gillian L., Hannivoort, Rebekka A ., Ciociaro, Demetrio, Ciociaro, Demetrio., Mu?oz, Ursula, Bugianesi, Elisabetta, Diana Vetter, Reeves, Helen L., Hannivoort, R., Lee, Ursula E., Rebekka A. Hannivoort, Bugianesi, Elisabetta., Young-Min Lee, Vetter, Diana, Hui, Kei Y., Friedman, Scott L., Gastaldelli, A. +80 morecore +1 more sourceJanus kinase 2 inhibition by pacritinib as potential therapeutic target for liver fibrosis
Hepatology, EarlyView., 2022 Diagram of the activation of the profibrotic and procontractile Janus kinase 2 (JAK2)/Ras homolog family member A/Rho‐kinase pathway and the inhibition of phosphorylated JAK2 by pacritinib to inhibit hepatic stellate cell activity. Abstract Background and Aims
Janus kinase 2 (JAK2) signaling is increased in human and experimental liver fibrosis with ...Sandra Torres, Cristina Ortiz, Nadine Bachtler, Wenyi Gu, Leon D. Grünewald, Nico Kraus, Robert Schierwagen, Christoph Hieber, Caroline Meier, Olaf Tyc, Maximilian Joseph Brol, Frank Erhard Uschner, Bart Nijmeijer, Christoph Welsch, Marie‐Luise Berres, Carmen Garcia‐Ruiz, Jose Carlos Fernandez‐Checa, Christian Trautwein, Thomas J. Vogl, Stefan Zeuzem, Jonel Trebicka, Sabine Klein +21 morewiley +1 more sourceGenome-wide association analysis identifies variants associated with nonalcoholic fatty liver disease that have distinct effects on metabolic traits [PDF]
, 2011 Nonalcoholic fatty liver disease (NAFLD) clusters in families, but the only known common genetic variants influencing risk are near PNPLA3. We sought to identify additional genetic variants influencing NAFLD using genome-wide association (GWA) analysis ...Palmer Cameron D., Schwartz, SM, Benjamin F Voight, Fox, Caroline S., Hwang, Shih-Jen, GIANT Consortium, Launer, Lenore, Hernaez, R, Melissa E. Garcia, Hwang, SJ, Pietiläinen, Kirsi Hannele, Harris, Tamara B, Mitchell, Braxton D., CRISPONI, LAURA, Butler, Johannah L, Massaro, J.M., Gudnason, V., Feitosa, MF, Jeanne M. Clark, Massaro, J., Jørgensen, Torben, O'Donnell Christopher J., Stephen M. Schwartz, Schwartz SM, Palmer, C., Eiriksdottir, Gudny, Joel N Hirschhorn, Kao W. H. Linda, Laura M. Yerges-Armstrong, Stephen M Schwartz, Jeanne M Clark, Borecki Ingrid B., Mitchell, Braxton, Smith, AV, null null, Palmer, C.D., Kao, W.H.L., Johannah L. Butler, Butler, Johannah L., Borecki, IB, Palmer CD, Salomaa, V., Hirschhorn, Joel, Borecki, Ingrid B., Johannah L Butler, Speliotes, Elizabeth K, Fox Caroline S., Shuldiner, Alan R., Fox CS, Hoffmann, Udo, Palmer, CD, Nalls, Michael, Garcia, Melissa E, Hwang SJ, Wu, Jun, Mary F Feitosa, Massaro, Joseph M., Eiriksdottir G, Schadt, EE, Voight, Benjamin F, Nalls, Michael A., Clark, Jeanne M., Eiriksdottir, G, Smith AV, O'Donnell, CJ, Sahani DV, NASH CRN, Schwartz Stephen M., Lauren J Kim, CJ, Butler Johannah L., Speliotes, Elizabeth K., Tamara B Harris, Speliotes, E.K., Feitosa, Mary F., Joseph M. Massaro, Caroline S. Fox, Smith, Albert V, Launer, Lenore J, Shuldiner Alan R., GOLD Consortium, Hoffmann, U, Harris, Tamara, Tamara B. Harris, Garcia Melissa E., Kao, W. H Linda, Albert V. Smith, Mitchell BD, Smith, A.V., Voight, BF, Voight, Benjamin F., Mary F. Feitosa, Alan R Shuldiner, Kim, L.J., Kao, W H Linda, Speliotes EK, Siscovick, DS, Schadt, Eric E., Fox, C.S., Vilmundur Gudnason, Sahani, Dushyant V, Ruben Hernaez, Raychaudhuri, Soumya, Cameron D Palmer, Dushyant V Sahani, Salomaa, Veikko, O'Donnell, Christopher J., Feitosa, Mary, Shuldiner AR, Carr, J Jeffrey, Harris, T.B., Speliotes Elizabeth K., Salomaa, V, Posthuma, D., Tomas, Marta, Palmer, Cameron D, Tomas, M, Wu Jun, Siscovick David S., Launer Lenore J., Palmer, Cameron, et al., de Geus, E.J.C.; id_orcid, Butler, J.L., Clark Jeanne M., Hernaez, R., Mitchell, Braxton D, Borecki, Ingrid B, Shuldiner, A.R., Voight Benjamin F., Benjamin F. Voight, Kao, WH Linda, Lenore J. Launer, Feitosa MF, Siscovick, David, Nalls, M.A., Carr, J. Jeffrey, Clark, JM, Garcia, Melissa E., Lenore J Launer, Hirschhorn Joel N., Hwang, S.J., Eiriksdottir, G., Launer, L.J., Laura M Yerges-Armstrong, Melissa E Garcia, Hwang, S., Christopher J O'Donnell, Yerges-Armstrong, Laura M., Clark, J., Kim Lauren J., Launer, Lenore J., Hirschhorn JN, Harris, Tamara B., Michael A. Nalls, Launer LJ, Boomsma, D.I.; id_orcid, J Jeffrey Carr, Massaro, JM, Braxton D. Mitchell, Posthuma, D.; id_orcid, Heijer, M. den, Shih-Jen Hwang, Siscovick, David S., Mitchell, BD, Siscovick DS, Gudnason V, Yerges-Armstrong, L.M., Launer, LJ (Lenore), Gudnason, Vilmundur, Veikko Salomaa, de Geus, E.J.C., O' DONNELL, Willemsen, G.; id_orcid, Mitchell, B., Shuldiner, Alan, Kim, Lauren J, Sahani Dushyant V., Smith Albert V., David S Siscovick, Schadt, Eric, Kao WH, Fox, CS, David S. Siscovick, Carr JJ, Butler, Johannah, Massaro, Joseph, Hoffmann U, Garcia, Melissa, Tomas Marta, Mitchell Braxton D., Christopher J. O'Donnell, Lokki, Marja-Liisa, Gudnason Vilmundur, Fox, Caroline, DIAGRAM Consortium, Schadt, E.E., Tomas M, Hirschhorn, J.N., Jun Wu, Nalls, M., Ingrid B Borecki, Launer, L., Harris TB, Palmer, Cameron D., O'Donnell, C.J., Nalls MA, Voight BF, Borecki IB, Salomaa V, Massaro, Joseph M, Voight, B.F., Nalls, MA, O'Donnell, Christopher J, Garcia, M., Harris Tamara B., Kao, W., Kao, WH, Elizabeth K Speliotes, Gudnason, V, Siscovick, D.S., Yerges-Armstrong, Laura, Siscovick, David S, Cameron D. Palmer, Smith, Albert, Garcia ME, Marta Tomas, Clark, Jeanne M, Eric E. Schadt, Hottenga, J.J., Wu, J, Caroline S Fox, Joel N. Hirschhorn, Wu, J., Hoffmann Udo, Schadt EE, Albert V Smith, Carr J. Jeffrey, Sahani, D.V., J. Jeffrey Carr, Michael A Nalls, Feitosa, Mary F, Kao, W.H., O'Donnell, Christopher, Kim LJ, Nalls Michael A., Feitosa Mary F., Schwartz, S.M., Smith, Albert V., Shuldiner, Alan R, Voight, Benjamin, Wu J, Alan R. Shuldiner, Borecki, Ingrid, Massaro Joseph M., Lauren J. Kim, Schwartz, Stephen M, SCUTERI, ANGELO, Kao, WHL, Speliotes, Elizabeth, Kim, LJ, Clark, Jeanne, Carr, J.J., Nalls, Michael A, Feitosa, M.F., Harris, TB, Willemsen, G., Hirschhorn, Joel N., Clark JM, Yerges-Armstrong, L., Ingrid B. Borecki, Eric E Schadt, Butler, J., Butler JL, Schwartz, Stephen, Yerges-Armstrong LM, Garcia, M.E., Hernaez Ruben, Shuldiner, AR, GIANT, Boomsma, D.I., Kim, L., Elizabeth K. Speliotes, O’Donnell, C., Clark, J.M., Yerges-Armstrong, Laura M, Kim, Lauren J., Garcia, ME, Joseph M Massaro, Mitchell, B.D., Massaro JM, Speliotes, EK, Kim, Lauren, Udo Hoffmann, Jansson, John-Olov,, W H Linda Kao, MAGIC Investigators, Launer, LJ, Shuldiner, A., Hirschhorn, Joel N, Salomaa Veikko, Dushyant V. Sahani, Hwang Shih-Jen, Tomas, M., Hernaez R, Geus, E.J.C. de, Borecki, I.B., Kao, W. H. Linda, Hwang, Shih Jen, Butler, JL, Sahani, Dushyant, Hirschhorn, JN, Sahani, Dushyant V., Speliotes, E., YERGES ARMSTRONG LM, Yerges-Armstrong Laura M., Hernaez, Ruben, Eiriksdottir Gudny, Sahani, DV, Gudny Eiriksdottir, Braxton D Mitchell, Schadt Eric E., Schadt, Eric E, Hoffmann, U., PAOLISSO, Giuseppe, Schwartz, Stephen M., W. H. Linda Kao, Carr, JJ, Yerges-Armstrong, LM, Fox, Caroline S, Kaplan, Robert C., Chalasani, Naga, Welch, Ryan, Assimes, Themistocles L., Sanna, Serena, Teslovich, Tanya M., Hengstenberg, Christian, Zgaga, Lina, Dasarathy, Srinivasan, Peters, Annette, Gyurkey, Grace, Kaprio, Jaakko, Ketkar, Shamika, Navarro, Pau, Qi, Lu, Monda, Keri L., Gejman, Pablo V., Lawrence, Robert W., Abecasis, Gonçalo R., Diehl, Anna Mae, White, Melanie, Valle, Timo T., Facheris, Maurizio F., Frayling, Timothy M., Jarvelin, Marjo-Riitta, Liu, Jianjun, Piercy, Dawn, Ludwig, Barbara, Wang, Chia, Killenberg, Paul, Kilpeläinen, Tuomas O., Almgren, Peter, Balmforth, Anthony J., Huikuri, Heikki V., Gräβler, Jürgen, Strachan, David P., Waeber, Gérard, Bergman, Richard N., König, Inke R., Ingelsson, Erik, Workalemahu, Tsegaselassie, Lajunen, Taina, Kwan, Samantha, Nelson, James, Gloyn, Anna L., Clark, Lisa, Lehtimäki, Terho, Vitart, Veronique, Iribarren, Carlos, Stringham, Heather M., Chasman, Daniel I., Weedon, Michael N., Selph, Kimberly, Mc, Steven A., Contos, Melissa J., Farooqi, I. Sadaf, Erdmann, Jeanette, O'Rahilly, Stephen, Loos, Ruth J. F., Roberts, Sarah, Hall, Per, Rafelt, Suzanne, Hicks, Andrew A., Munroe, Patricia B., Dupuis, Josée, Mägi, Reedik, Quertermous, Thomas, Gaget, Stefan, Gyllensten, Ulf, Dehghan, Abbas, Manunta, Paolo, Perola, Markus, Wallaschofski, Henri, Heard-Costa, Nancy L., Ruokonen, Aimo, Sargeant, Carol, Molleston, Jean, King, Debra, Polasek, Ozren, Koskinen, Seppo, Ziegler, Andreas, Dixon, Anna L., van Duijn, Cornelia M., Bass, Nathan M., Smith, Melissa, Klipsch, Ann, Raitakari, Olli, Randall, Joshua, Zhang, Qunyuan, Wilson, James F., Wiegand, Susanna, Bhimalli, Prajakta, Robertson, Neil R., Schlessinger, David, Illig, Thomas, Hoesel, Volker, Rogers, Nicholette, Ruth Sargent, P. A. -C., Myers, Richard H., Laakso, Markku, Hayes, Richard B., Knowles, Joshua W., Buchanan, Thomas A., Visscher, Peter M., Lamina, Claudia, Chen, Chih-Mei, Ngwa, Julius S., Wheeler, Eleanor, Lanzani, Chiara, Duan, Jubao, Purcell, Shaun, Luan, Jian'an, Edwards, Kevin, Elosua, Roberto, Caulfield, Mark J., Kleiner, David, Jeffrey Carr, J., Ebrahim, Shah, Greenawalt, Danielle M., Sandhu, Manjinder S., Guiducci, Candace, Yeh, Matthew, Smit, Jan H., Bragi Walters, G., MAGIC Investigators, ,, Hall, Alistair S., Berndt, Sonja I., Kvaløy, Kirsti, Campbell, Harry, Narisu, Narisu, Folsom, Aaron R., Rayner, Nigel W., Schwimmer, Jeffrey B., Watanabe, Richard M., Allen, Hana Lango, Graham, Martin, Day, Ian N. M., Hu, Frank B., Atwood, Larry D., Mooney, Jody, Mulic, Rosanda, Groop, Leif C., Tammesoo, Mari-Liis, Brancati, Fred, Chanock, Stephen J., Franklin, Christopher S, Jacobs, Kevin B., Colvin, Ryan, Grönberg, Henrik, Peltonen, Leena, Widen, Elisabeth, Boehnke, Michael, Thomson, Brian, Brunt, Elizabeth, Johansson, Åsa, Green, Mika, Preuss, Michael, Witte, Daniel R., Steinthorsdottir, Valgerdur, Pichler, Irene, Silander, Kaisa, Xu, Jianfeng, Zitting, Paavo, Spector, Timothy D., Egan, Josephine M, Wilson, Laura, Khaw, Kay-Tee, Lecoeur, Cecile, Platou, Carl G. P., Stefansson, Kari, Cappuccio, Francesco P., Boomsma, Dorret I., Marek, Diana, Kovacs, Peter, Tönjes, Anke, Chatterjee, Nilanjan, Jones, Amy, Rissanen, Aila, Kraft, Peter, Stager, Margaret, Soranzo, Nicole, Hayward, Caroline, Schwarz, Peter, Igl, Wilmar, Filipowski, Danuta, Gustafsson, Stefan, Gieger, Christian, Viikari, Jorma, Hinney, Anke, NASH CRN, ,, Van Natta, Mark, Barlow, Sarah, Tyrer, Jonathan P., Hottenga, Jouke Jan, Kuusisto, Johanna, Thorleifsson, Gudmar, Neville, Matt J., Watkins, Hugh, Arnold, Alice M., Paré, Guillaume, Scott, Laura J., Oostra, Ben, Pellikka, Niina, Aspelund, Thor, van Meurs, Joyce B. J., Gottfried, Marcia, Boes, Tanja, Song, Kijoung, Petcharaporn, Lita, Schunkert, Heribert, Kathiresan, Sekar, Jula, Antti, Froguel, Philippe, Belt, Patricia, Wild, Sarah H., Lavine, Joel E., Uitterlinden, André G., Jansson, John-Olov, Sanyal, Arun J., Ripatti, Samuli, Connell, John, Yates, Katherine, Ridker, Paul M., Tuomilehto, Jaakko, Ouwehand, Willem H., Jewell, Elizabeth, Lantieri, Olivier, McKnight, Barbara, Pedersen, Oluf, Goddard, Michael E., Amin, Najaf, Linda Kao, W. H., Kettunen, Johannes, Rosenthal, Philip, Jackson, Anne U., Elliott, Paul, Vogel, Carla I. G., Isaacson, Milana, den Heijer, Martin, Hoofnagle, Jay H., Lanzani C, Boerwinkle, Eric, Wabitsch, Martin, Heinrich, Joachim, Vedantam, Sailaja, Perry, John R. B., Fischer-Posovszky, Pamela, Stewart, Susan, Rzehak, Peter, Wood, Andrew R., Lettre, Guillaume, Friedrich, Nele, Hartikainen, Anna-Liisa, Lee, Lydia, Surakka, Ida, Goel, Anuj, Erdos, Michael R., Shi, Jianxin, Behling, Cynthia, Havulinna, Aki S., Freimer, Nelson B., Hebebrand, Johannes, ?, ?, Zhao, Jing Hua, Yang, Jian, Winkler, Thomas W., Kaplan, Lee M., Kiemeney, Lambertus A., Kajantie, Eero, Donithan, Michele, Uda, Manuela, Isomaa, Bo, Prokopenko, Inga, Parker, Alex N., Bergmann, Sven, Groves, Christopher J., Lawlor, Debbie A., Cavalcanti-Proença, Christine, Steel, Tessa, Sparsø, Thomas, Bringman, Diane, Henneman, Peter, Visvikis-Siest, Sophie, Liu, Yao-Chang, Thompson, John R., Savolainen, Markku J., Ridderstråle, Martin, McArdle, Wendy L., Scherag, Susann, McCullough, Arthur, Pan, Yi-Ping, Grarup, Niels, Aben, Katja K., Adrienne Cupples, L., Chen, Yii-Der Ida, Ferreira, Teresa, Busonero, Fabio, Miriel, Laura, Park, Ju-Hyun, Stead, Alice, Haritunians, Talin, Bryan, Daphne, Penninx, Brenda W., Wright, Alan F., Thiering, Elisabeth, Tardif, Jean-Claude, Morris, Andrew P., Coin, Lachlan J. M., Ong, Ken K., Fuchs, Michael, Sinisalo, Juha, Homuth, Georg, Deloukas, Panos, Jarick, Ivonne, Wiklund, Fredrik, Wareham, Nicholas J., Laitinen, Jaana, Hawkins, Carol, Brown, Morris J., Stumvoll, Michael, Karpe, Fredrik, Timpson, Nicholas J., Pietiläinen, Kirsi H., Hofman, Albert, Durelle, Janis, Glazer, Nicole L., Meitinger, Thomas, Li, Shengxu, Neuschwander-Tetri, Brent A., Luben, Robert N., Bornstein, Stefan R., Moffatt, Miriam F., Vuppalanchi, Raj, Krude, Heiko, Robuck, Patricia R., McCarthy, Anne, Sandhu, Bimalijit, Wichmann, H. -Erich, Sternberg, Alice, Stein, Tanya, Guy, Cynthia, Hassanein, Tarek, Bambha, Kiran, Doney, Alex, Hveem, Kristian, Mohlke, Karen L., Midthjell, Kristian, Heid, Iris M., Lindgren, Cecilia M., Kutalik, Zoltán, Hattersley, Andrew T., Abdelmalek, Manal, Sirlin, Claude, Kaakinen, Marika, Martin, Nicholas G., Samani, Nilesh J., Bouatia-Naji, Nabila, Alavere, Helene, Langenberg, Claudia, Barroso, Inês, Siegner, Joan, Eriksson, Johan G., Doo, Edward, Carola Zillikens, M., Geus, Eco J. C., North, Kari E., Biebermann, Heike, Teder-Laving, Maris, Ragozzino, Linda, Swift, Amy, Pouta, Anneli, Lorentzon, Mattias, Sanders, Alan R., Schreiber, Stefan, Rivadeneira, Fernando, Derdoy, Jose, Grallert, Harald, Willemsen, Gonneke, Saramies, Jouko, Vatin, Vincent, Fu, Mao, Clarke, Robert, Rosenthal, Monique, Luketic, Velimir A. C., Mangino, Massimo, Tonascia, James, Barlassina, Christina, Ünalp, Aynur, Thorsteinsdottir, Unnur, Willer, Cristen J., Macciardi, Fabio, Hassanali, Neelam, Cummings, Oscar W., Stephens, Jonathan, Chines, Peter, John, Ulrich, Meyre, David, McCarthy, Mark I., Saxena, Richa, Hunter, David J., Marre, Michel, Merriman, Raphael, Navarro, Pau; id_orcid, Boeing, Heiner, O'DONNELL CJ, Jousilahti, Pekka, Kowdley, Kris V., Fisher, Eva, Rudan, Igor, Felix, Stephan B., Sandholt, Camilla, Reinehr, Thomas, Beckmann, Jacques S., Smith, George Davey, Morken, Mario A., van Ommen, Gert-Jan, Nelis, Mari, Ben-Shlomo, Yoav, White, Charles C., Alibrandi, Maria T. S., Everhart, Jay, Esko, Tõnu, Cooper, Matthew N., Absher, Devin M., Estrada, Karol, Johnson, Toby, Rief, Winfried, Gjesing, Anette P., GIANT Consortium, ,, MANUNTA P, Saunders, Cheryl, Scherag, Andre, Bennett, Amanda J., Hoffmann, Joyce, Nemesh, James, Kim, Wana, Heath, Andrew C., van Wingerden, Sophie, Blakemore, Alexandra I. F., Hui, Jennie, Pabst, Mark, Gold Consortium, ,, Montgomery, Grant W., Goyette, Philippe, Ferrell, Linda D., Levinson, Douglas F., Thompson, Judy, Bonnycastle, Lori L., Balkau, Beverley, Melander, Olle, Liang, Liming, Kolcic, Ivana, Segrè, Ayellet V., Seeff, Leonard, Kinnunen, Leena, Rybin, Denis, Nieminen, Markku S., Hansen, Torben, Sovio, Ulla, Witteman, Jacqueline C., Waite, Lindsay L., Nyholt, Dale R., Beilby, John P., Schipf, Sabine, Peters, Marjolein J., James, Alan L., O'Connell, Jeffrey R., Weyant, Robert J., Boyett, Sherry, Pramstaller, Peter P., Ohlsson, Claes, Kähönen, Mika, Tuomi, Tiinamaija, Metspalu, Andres +803 morecore +5 more sourcesInterleukin‐18 signaling promotes activation of hepatic stellate cells in mouse liver fibrosis
Hepatology, EarlyView., 2022 Interleukin‐18 signaling promotes activation of hepatic stellate cells in mouse liver fibrosis. Abstract Background and Aims
Nucleotide‐binding oligomerization domain‐like receptor‐family pyrin domain‐containing 3 (NLRP3) inflammasome activation has been shown to result in liver fibrosis.Jana Knorr, Benedikt Kaufmann, Maria Eugenia Inzaugarat, Theresa Maria Holtmann, Lukas Geisler, Jana Hundertmark, Marlene Sophia Kohlhepp, Laela M. Boosheri, Daisy R. Chilin‐Fuentes, Amanda Birmingham, Kathleen M. Fisch, Joel D. Schilling, Sven H. Loosen, Christian Trautwein, Christoph Roderburg, Münevver Demir, Frank Tacke, Hal M. Hoffman, Ariel E. Feldstein, Alexander Wree +19 morewiley +1 more sourceElevated endotoxin levels in non-alcoholic fatty liver disease [PDF]
, 2010 Background: Emerging data indicate that gut-derived endotoxin may contribute to low-grade systemic inflammation
in insulin resistant states. This study aimed to examine the importance of serum endotoxin and inflammatory markers
in non-alcoholic fatty ...Ashour, E., Steven J Creely, Youssef-Elabd, E., Youssef-Elabd, Elham M., Harte, A., Abdalla, M., Creely, S., Ashour Esmat, da Silva, Nancy F., McTernan Philip G, Mohga S Abdalla, Day, C.P., Day, Christopher Paul, Billyard, T., Burt, Alastair D., Burt Alastair D, Philip G McTernan, Kumar, S., Elham M Youssef-Elabd, da Silva, N.F., Alison L Harte, Burt, A.D., Nancy F da Silva, Amin, Ashraf I., Tripathi, Gyanendra, Sharada, H., Burt, A., McTernan, P. G., Billyard, Thomas, da Silva, N., Harte, A.L., Day Christopher P, Youssef-Elabd Elham M, Tripathi Gyanendra, Alastair D Burt, Sharada, Hayat M., Hayat M Sharada, Kumar Sudhesh, Abdalla Mohga S, Sharada, H.M., Day, C., Abdalla, Mohga S., Sudhesh Kumar, Creely, S.J., McGee Kirsty C, Esmat Ashour, McTernan, P., Abdalla, M.S., Tripathi, G., McGee, K.C., Youssef-Elabd, E.M., Kirsty C McGee, Christopher P Day, Ashour, Esmat, McGee, K., Billyard Thomas, Gyanendra Tripathi, Thomas Billyard, Kumar, Sudhesh, Amin Ashraf I, Amin, A., da Silva Nancy F, Harte, A. L., Ashraf I Amin, McTernan, P.G., Creely, Steven J., McGee, K. C., Harte Alison L, Creely Steven J, Sharada Hayat M, Amin, A.I. +70 morecore +1 more sourceNoninvasive tests for nonalcoholic fatty liver disease in a multi‐ethnic population: The HELIUS study
Hepatology Communications, EarlyView., 2022 Abstract
Nonalcoholic fatty liver disease (NAFLD) is increasing in prevalence and severity globally, prompting noninvasive testing, yet limited data exist on noninvasive liver tests (NITs) including transient elastography (TE) in ethnically diverse populations.Anne‐Marieke van Dijk, Yasaman Vali, Anne Linde Mak, Henrike Galenkamp, Max Nieuwdorp, Bert‐Jan van den Born, Adriaan Georgius Holleboom +6 morewiley +1 more source
