Results 141 to 150 of about 101,002 (279)

Effect of pentoxifylline on histological activity and fibrosis of nonalcoholic steatohepatitis patients: A one year randomized control trial [PDF]

, 2017
Shahinul Alam, SKM Nazmul Hasan, Golam Mustafa, Mahabubul Alam, Mohammad Amjad Kamal, Nooruddin Ahmad   +5 more
openalex   +1 more source

Ashwagandha: Is It Safe? Part 2: A Preclinical Evidence Review

Phytotherapy Research, EarlyView.
ABSTRACT The preclinical evidence for the safety of ashwagandha (Withania somnifera (L.) Dunal, AS) is reviewed, and its preparations (extracts) and constituents, from the general toxicity in animal models to in vitro and cell culture studies, which may elucidate mechanisms of action and explain clinical case reports.
Elizabeth M. Williamson, Thomas Brendler
wiley   +1 more source

Organic solute transporter OSTα/β is overexpressed in nonalcoholic steatohepatitis and modulated by drugs associated with liver injury [PDF]

, 2018
Melina M. Malinen, Izna Ali, Jacqueline Bezençon, James J. Beaudoin, Kim L. R. Brouwer   +4 more
openalex   +1 more source

Hepatic fibrosis in patients diagnosed with rheumatoid arthritis and psoriatic arthritis receiving methotrexate: A cross‐sectional analysis using transient elastography

Rheumatology &Autoimmunity, EarlyView.
Hepatic fibrosis and metabolic syndrome are more prevalent in PsA patients treated with methotrexate, compared to RA patients. Metabolic syndrome is associated with the risk of hepatic fibrosis in patients diagnosed with PsA and RA even after adjustment forcumulative methotrexate exposure.
Ratchaya Lertnawapan, Soonthorn Chonprasertsuk, Sith Siramolpiwat, Kanon Jatuworapruk   +3 more
wiley   +1 more source

Narcolepsy Is Associated With Subclinical Cardiovascular Disease as Early as Childhood: A Big Data Analysis

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Narcolepsy is linked to adverse cardiovascular disease (CVD) outcomes, but few studies have examined its associations with subclinical CVD, including in children.
Christopher N. Kaufmann, Munaza Riaz, Haesuk Park, Wei‐Hsuan Lo‐Ciganic, Debbie Wilson, Emerson M. Wickwire, Atul Malhotra, Rakesh Bhattacharjee   +7 more
doaj   +1 more source

Ablation of the deubiquitinase USP15 ameliorates nonalcoholic fatty liver disease and nonalcoholic steatohepatitis [PDF]

, 2023
Jung-Hwan Baek, Myung Sup Kim, Hye Ryeon Jung, Min-Seon Hwang, Chan-Ho Lee, Dai Hoon Han, Yong‐ho Lee, Eugene C. Yi, Seung‐Soon Im, Ilseon Hwang, Kyungeun Kim, Joon‐Yong Chung, Kyung‐Hee Chun   +12 more
openalex   +1 more source

Histopathological Characterization and Differential Expression of miRNAs in Male Pediatric Patients With Lichen Sclerosus

Andrology, EarlyView.
ABSTRACT Background Lichen sclerosus is a chronic, inflammatory, scarring disease of the skin that manifests mostly in the genital region. Objective We studied the histomorphological characteristics, grade, and pattern of inflammation in male pediatric patients with lichen sclerosus.
Valerie Flammang, Arndt Hartmann, Robert Stöhr, Katrin Weigelt, Carol Geppert, Frederik A. Stuebs, Matthias W. Beckmann, Bernd Wullich, Helge Taubert, Marios Marcou, Sven Wach   +10 more
wiley   +1 more source

Therapeutic efficacy of an angiotensin II receptor antagonist in patients with nonalcoholic steatohepatitis [PDF]

, 2004
Shiro Yokohama, Masashi Yoneda, Masakazu Haneda, Satoshi Okamoto, Mituyoshi Okada, Kazunobu Aso, Takenao Hasegawa, Yoshihiko Tokusashi, Naoyuki Miyokawa, Kimihide Nakamura   +9 more
openalex   +1 more source

Gestational Melatonin Supplementation Attenuates Maternal Sleep Deprivation‐Induced Steatohepatitis Susceptibility in Offspring

Cell Proliferation, EarlyView.
Maternal SD during pregnancy enhances the development of diet‐induced NASH in adult offspring of both sexes through an NR4A3‐dependent mechanism, characterised by heightened inflammation and increased apoptosis. Maternal melatonin supplementation effectively alleviates this increased susceptibility to NASH in offspring.
Fei Guo, Zexin Yang, Junsen She, Chen Fang, Yizhi Hu, Hefeng Huang, Ling Gao   +6 more
wiley   +1 more source

Resmetirom: Finally, the Light at the End of the NASH Tunnel?

Livers
Nonalcoholic steatohepatitis (NASH) is a double composite word that was first coined in 1980 by Ludwig and Colleagues [...]
Amedeo Lonardo
doaj   +1 more source