Results 141 to 150 of about 98,461 (251)

Identification and Characterization of Three Novel Biomarkers for Mixed/Cholestatic Drug‐Induced Liver Injury

open access: yesHepatology Research, EarlyView.
Three metabolites, pyroglutamylglycine (pyroGluGly), phenylalanine (Phe), and phenylalanyltryptophan (PheTrp), were identified as candidate DILI biomarkers. The serum concentrations of pyroGluGly, Phe, and PheTrp demonstrated a high differentiating ability in patients with mixed and cholestatic DILI compared with those in patients who recovered from ...
Kosuke Saito   +22 more
wiley   +1 more source

NASH IN CHILDREN – A SHORT REVIEW

open access: yesKhyber Medical University Journal, 2010
Nonalcoholic fatty liver disease (NAFLD) describes a hepatic disorder with the typical characteristics of an alcoholic liver disease without alcohol consumption.
M Fazal Karim   +3 more
doaj  

Diacylglycerol acyltranferase 1 anti-sense oligonucleotides reduce hepatic fibrosis in mice with nonalcoholic steatohepatitis [PDF]

open access: bronze, 2007
Kanji Yamaguchi   +9 more
openalex   +1 more source

Epidemiology of Metabolic Dysfunction–Associated Steatotic Liver Disease in South Asian Ethnicities: A Systematic Review and Meta‐Analysis

open access: yesJournal of Gastroenterology and Hepatology, EarlyView.
ABSTRACT Background and Aims People of South Asian ethnicities are at increased risk of metabolic syndrome, but the epidemiology of metabolic dysfunction–associated steatotic liver disease (MASLD) in this population remains poorly understood. This systematic review and meta‐analysis assesses the prevalence, cross‐sectional severity, and clinically ...
Michael James   +4 more
wiley   +1 more source

Lipid Autophagy: An Idea for the Treatment of Diabetic Nephropathy With Ginseng and Its Active Compounds

open access: yeseFood, Volume 6, Issue 6, December 2025.
In light of the steadily increasing incidence of diabetic nephropathy (DN), this review explores the potential of edible natural products to slow disease progression, addressing the limitations of conventional clinical drug therapies. Key findings show that ginsenosides, the active compounds in edible ginseng, regulate lipid autophagy, reducing ...
Rui Zhang   +7 more
wiley   +1 more source

A novel S1PR4 functional antagonist prevents nonalcoholic steatohepatitis by deactivating the NLRP3 inflammasome without causing lymphopenia [PDF]

open access: gold, 2020
Ki‐Up Lee   +21 more
openalex   +1 more source

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