Results 151 to 160 of about 98,461 (251)
Design of the phase 3
, 2023 Stephen A. Harrison +13 more
openalex +1 more source
Extracellular Vesicles in Nonalcoholic Fatty Liver Disease: Mechanisms and Therapeutic Opportunities
iNew Medicine, Volume 1, Issue 1, December 2025.The role of extracellular vesicles (EVs) in the progression of nonalcoholic fatty liver disease (NAFLD). Donor cells release EVs containing various molecules such as cholesterol, ceramide, sphingomyelin, miRNA, DNA, proteins, and lipids. These EVs are taken up by multiple recipient cells including Kupffer cells, adipocytes, β cells, adipose tissue ...
Yunsheng Dong +12 more
wiley +1 more source
NGM282: a step forward in the nonalcoholic steatohepatitis treatment landscape?
, 2018 Luca Valenti, Valério Nobili
openalex +2 more sources
Journal of Ultrasound in Medicine, Volume 44, Issue 12, Page 2243-2255, December 2025.Objectives To evaluate the diagnostic performance of ultrasound‐derived fat fraction (UDFF) in detecting and grading hepatosteatosis using liver histology as the reference, and to assess the effectiveness of point shear wave elastography (pSWE), UDFF, and auto‐pSWE in diagnosing steatohepatitis and detecting fibrosis in metabolic dysfunction‐associated
Ahmet Burak Kale +5 more
wiley +1 more source
New Medications in the Treatment of Nonalcoholic Steatohepatitis
, 2018 Scot Walker
openalex +2 more sources
Liver International Communications, Volume 6, Issue 4, December 2025.ABSTRACT Chemokine receptor type 5 (CCR5) is upregulated in the livers of patients with metabolic dysfunction–associated steatohepatitis (MASH). Leronlimab, a humanised IgG4κ monoclonal antibody, directly binds the extracellular domains of CCR5, modulates downstream signalling and potentially can slow, reverse or prevent fibrosis. The aim of this study
Melissa Palmer +10 more
wiley +1 more source
Fungal‐Bacterial Dysbiosis in IBD: Microbial Biomarkers of Disease Activity
MicrobiologyOpen, Volume 14, Issue 6, December 2025.This study characterizes bacterial, fungal, and viral communities in Crohn's disease and ulcerative colitis using intestinal and faecal samples. Distinct microbial signatures and inter‐kingdom interactions were identified, with taxa such as Prevotella, Fusobacterium, and Roseburia linked to disease activity.
Elisa Arribas‐Rodríguez +12 more
wiley +1 more source
Biomarkers and subtypes of deranged lipid metabolism in non-alcoholic fatty liver disease. [PDF]
, 2019 Nonalcoholic fatty liver disease (NAFLD) is a heterogeneous and complex disease that is imprecisely diagnosed by liver biopsy. NAFLD covers a spectrum that ranges from simple steatosis, nonalcoholic steatohepatitis (NASH) with varying degrees of fibrosis,
Alonso, Cristina +3 more
core
MicrobiologyOpen, Volume 14, Issue 6, December 2025.Probiotic supplementation with Bifidobacterium adolescentis and Bifidobacterium bifidum, especially combined, ameliorates liver injury and metabolic dysfunction in HFD+STZ‐induced MAFLD rats by enhancing lipophagy, preserving liver structure, and improving serum lipid and liver function markers.
Mahtab Mehboodi +12 more
wiley +1 more source