Results 171 to 180 of about 98,461 (251)

The function role of HIGD1A in nonalcoholic steatohepatitis from chronic hepatitis B

, 2023
Minran Li, Jinzhong Li, Dehua Wang, Tao‐yuan Li, Lihong Ye, Xujing Liang, Hai-cong Zhang, Zhiquan Liu, Xuedong Zhang, Junqing Li, Yunyan Liu, Calvin Q. Pan, Erhei Dai   +12 more
openalex   +1 more source

Benzoxazole Derivatives as Potent FXR and PPARα Dual Agonists With Anti‐Fibrotic and Metabolic Regulatory Effects

MedComm, Volume 6, Issue 11, November 2025.
MHY5396, a benzoxazole derivative, functions as a potent dual FXR and PPARα agonist. It exhibits significant anti‐fibrotic and metabolic regulatory effects, effectively improving liver and kidney fibrosis in experimental models. These findings highlight its potential as a therapeutic candidate for fibrosis and metabolic disorders.
Mi‐Jeong Kim, Dong‐Gyun Han, Hyeon Seo Park, Sugyeong Ha, Sang Gyun Noh, Jeongwon Kim, Ji‐an Yoo, Byeong Moo Kim, Khas‐Erdene Battogtokh, Soohwan Oh, Youngmi Jung, Youngsuk Jung, Hae Young Chung, Hyung Ryong Moon, In‐Soo Yoon, Ki Wung Chung   +15 more
wiley   +1 more source

Mucosal‐Associated Invariant T Cells: Origins, Biological Functions, Diseases, and Therapeutic Targets

MedComm, Volume 6, Issue 11, November 2025.
Mucosa‐associated invariant T (MAIT) cells are an evolutionarily conserved class of innate‐like T lymphocytes that rely on MR1 molecules to recognize microbial metabolites and play a central role in immune surveillance and inflammatory regulation.
Cheng Zhu, Qian Huai, Yishan Du, Xingyu Li, Fumin Zhang, Yongkang Zhang, Mengwei Wu, Ying Dai, Xiaolei Li, Hanren Dai, Hua Wang   +10 more
wiley   +1 more source

Shugan Xiaozhi Decoction attenuates nonalcoholic steatohepatitis by modulating oxidative stress and AMPK pathway. [PDF]

BMC Complement Med Ther
Yang R, Feng L, Gong Z, Yang H, Du H, Chen J, Qin M, Chen N, Huang H, Wang P, Wu Q, Xing Y.   +11 more
europepmc   +1 more source

Bariatric Surgery Reduces Features of Nonalcoholic Steatohepatitis in Morbidly Obese Patients [PDF]

, 2015
Guillaume Lassailly, Robert Caïazzo, David Buob, Marie Pigeyre, Hélène Verkindt, Julien Labreuche, Violeta Raverdy, Emmanuelle Leteurtre, Sébastien Dharancy, Alexandre Louvet, Monique Romon, Alain Duhamel, François Pattou, Philippe Mathurin   +13 more
openalex   +1 more source

Discovering Heterogeneous Leukocytes Subsets Associated With Alcoholic Steatohepatitis by scRNAseq Analysis

MedComm, Volume 6, Issue 11, November 2025.
In this study, we explored comprehensive profiling of heterogeneous immune leukocytes at a single‐cell level using scRNAseq analysis to discover the regulation of inflammatory‐mediated liver fibrosis in ALD‐induced mice compared with healthy controls.
Haribalan Perumalsamy, Sehee Park, Ji Eun Kim, Xiao Xiao, Hye Young Kim, Dae Won Jun, Tae‐Hyun Yoon   +6 more
wiley   +1 more source

The Construction and Performance Evaluation of a Risk Prediction Model for Nonalcoholic Steatohepatitis Based on Serological Markers. [PDF]

Gastroenterol Res Pract
Huang D, Zhang W, Fang Y, Liu T, Zhou D.
europepmc   +1 more source

Association of histologic disease activity with progression of nonalcoholic fatty liver disease [PDF]

, 2019
Brundt, Elizabeth M, et al,, Kleiner, David E   +2 more
core   +1 more source

Attenuating effects of allantoin on oxidative stress in a mouse model of nonalcoholic steatohepatitis

, 2021
Zeinab Hamidizad, Azam Moslehi, Maryam Rastegarpanah   +2 more
openalex   +1 more source

The Gut‒Liver Axis in Liver Disease: Molecular Mechanisms and Therapeutic Targets

MedComm, Volume 6, Issue 11, November 2025.
The global burden of liver disease is increasing, and gut‐liver axis dysregulation is a key driver. This article explains its mechanisms in various liver diseases and explores targeted therapeutic strategies, aiming to provide new insights into liver disease treatment.
Zhiji Chen, Siqi Liao, Suhua Wu, Siyuan Chen, Qin Tang, Li Zhou, Xiaoqin Li, Huiyi Hu, Jiayao Xu, An Zhang, Song He, Zhi‐Hang Zhou   +11 more
wiley   +1 more source