Results 131 to 140 of about 19,530 (228)

Peptide‐based responsive molecular fluorescent probes for precision oncology

Responsive Materials, EarlyView.
Peptide‐based responsive fluorescent probes have emerged as adaptive functional materials for precision tumor theranostics, combining tumor‐selective recognition, programmable stimulus responsiveness, and modular tunability. They enable high‐contrast imaging, intraoperative guidance, real‐time monitoring, and multimodal applications, while next ...
Xing Wang, Wen Liu, Jiahao Zhang, Wanqi Wang, Zhicheng Jin, Yuqi Tang, Quan Li   +6 more
wiley   +1 more source

EDA Complex-Mediated C(sp³)-H Cross-Dehydrogenative Coupling Enables Synthesis of Noncanonical <i>α</i>,<i>β</i>-Diamino Acids. [PDF]

European J Org Chem
Sachidanandan K, Stenftenagel C, Joshy A, Cluff AM, Laulhé S.   +4 more
europepmc   +1 more source

Photo‐responsive carbon dots for pyroptosis‐mediated anti‐tumor application

Responsive Materials, EarlyView.
Photo‐responsive CDs generate ROS to induce tumor cell pyroptosis, thereby stimulating antitumor immunity. Abstract Pyroptosis refers to a kind of lytic programmed cell death, characterized by the release of pro‐inflammatory cytokines during the process. Owing to its immune response stimulation ability, pyroptosis has garnered considerable attention in
Lingyun Li, Xue Wu, Zekun Yan, Jun Wu, Caishi Huang, Songnan Qu   +5 more
wiley   +1 more source

Splice site diversity and abundance of noncanonical introns in diplonemids (Diplonemea, Euglenozoa). [PDF]

RNA
Thakur PK, Butenko A, Karásek F, Svobodová M, Faktorová D, Pavlisková H, Varga V, Horák A, Lukeš J, Staněk D.   +9 more
europepmc   +1 more source

Recent Advances in Photocatalyst‐Driven Protein Labeling and Proximity Mapping

The Chemical Record, EarlyView.
Photocatalyst‐driven protein labeling and proximity mapping have rapidly advanced as powerful strategies for spatiotemporal control in complex biological environments. This review integrates recent developments across single‐electron transfer and energy transfer‐based mechanisms and highlights how catalyst design, reactive intermediates, and diffusion ...
Shinichi Sato, Kazuki Miura, Juki Nakao, Hiroyuki Nakamura   +3 more
wiley   +1 more source

Degradation Determinants Are Abundant in Human Noncanonical Proteins and Minor Annotated Isoforms. [PDF]

Genome Biol Evol
Casola C, Owoyemi A, Vakirlis N.
europepmc   +1 more source

Deciphering diverse cell‐death patterns to predict the prognosis and potential therapy target of hepatocellular carcinoma patients

VIEW, EarlyView.
Abstract Ninety percent of all primary liver malignancies are hepatocellular carcinomas (HCC), making liver cancer the third most common cause of cancer‐associated mortality. Different patterns of programmed cell death (PCD) are crucial for the survival of tumors, and they might serve as a prognostic marker for HCC.
Lin Ding, Qian Li, Wenjing Yang, Te Liu, Tongtong Tian, Yu Liu, Chunyan Zhang, Baishen Pan, Beili Wang, Fan Wu, Wei Guo   +10 more
wiley   +1 more source

Single-Cell Transcriptomes and Phylogenomic Analysis of Uncultivated Oxymonads. [PDF]

J Eukaryot Microbiol
Trznadel M, Lax G, Boscaro V, Scheffrahn RH, Nalepa CA, Kolisko M, Keeling PJ.   +6 more
europepmc   +1 more source

Nanobodies as next‐generation targeting platforms: From discovery technologies to translational biomedicine

VIEW, EarlyView.
Nanobodies, derived from the variable domains of camelid heavy‐chain‐only antibodies, have emerged as transformative biomedical tools due to their nanoscale size, exceptional stability, and unique capacity to recognize cryptic epitopes. This review provides a comprehensive overview of the field, outlining the structural and biochemical features of ...
Zhenrui Ye, Xianyang Li, Meixiao Zhan
wiley   +1 more source

Canonical and noncanonical NF-κB signaling in uveal melanoma: mechanisms, microenvironment, and therapeutic modulation. [PDF]

Med Hypothesis Discov Innov Ophthalmol
Jalali S, Dianat I, Baghi Keshtan S, Izadfar R, Esfandiari HR, Lohrasbi G, Firuzpour F.   +6 more
europepmc   +1 more source