Results 151 to 160 of about 224 (182)
European Journal of Organic Chemistry, Volume 29, Issue 21, 4 June 2026.A practical and scalable route to C1 and C2 lysine homologs has been developed using Hofmann degradation of N‐protected L‐asparagine and L‐glutamine as the key step. These short‐tether scaffolds enable efficient synthesis of diverse Fmoc‐protected noncanonical amino acids (ncAAs) bearing donor, acceptor, redox‐active, and fluorescent residues.
Adelaide R. Mashweu +7 more
wiley +1 more source
Molecular Oncology, Volume 20, Issue 6, Page 1429-1452, June 2026.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
FEBS Open Bio, Volume 16, Issue 6, Page 1087-1101, June 2026.dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source
Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells
FEBS Open Bio, Volume 16, Issue 6, Page 1150-1165, June 2026.Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi +7 more
wiley +1 more source
Becoming Noncanonical: The Case Against Willa Cather
American Quarterly, 1988 IN THE 1920S WILLA CATHER ACHIEVED BOTH CRITICAL ACCLAIM AND POPULAR success. So confident was she of her ability to attract contemporary and future readers that in 1927 she asked her publisher Alfred Knopf for a one percent increase in her royalties for Death Comes for the Archbishop.
Sharon O’Brien
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A case of neuroblastoma in DICER1 syndrome: Chance finding or noncanonical causation?
Pediatric Blood & Cancer, 2017 AbstractDICER1 syndrome is an inherited disorder associated with at least a dozen rare, mainly pediatric‐onset tumors. Its characterization remains incomplete. Some studies suggested that neuroblastoma (NB) may be involved in this syndrome. Here, we describe the case of a 14‐year‐old female presenting with a multinodular goiter (MNG) and a collision ...
Avi Saskin +6 more
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Brain and Language, 2005 Despite this, none of the participants showed any improvements in comprehension of the same sentence structure. After production treatment, each participant performed within the individual pre-treatment chance level in comprehension. DISCUSSION The finding that none of the participants improved in comprehension of sentences successfully trained in ...
Astrid Schröder +6 more
openalex +4 more sources
Prospects, 1996 The authors of these passages share more than a belief in the efficacy of the category of “race” and a need to assert pride in their African-American heritage. Both have, of late, experienced notable recognition and affirmation from constituencies that typically evince little interest in black Americans and their culture.
Stanley Corkin, Phyllis Frus
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The Strange Case of the Noncanonical Lamina: Deep Divisions in Nuclear Organisation?
The nuclear envelope is subtended in most eukaryotes by a proteinaceous lamina, a network that has been recognised since the 1950s. Originally considered as a simple structural support, it is now clear that the lamina can be highly dynamic and participates in a multitude of functions, including transcriptional and epigenetic regulation, definition of ...
Mark C. Field, Michael P Rout
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