Results 111 to 120 of about 15,499,840 (341)

NONCOMMUNICABLE DISEASE CONDITIONS AND HIV IN RURAL AND URBAN SOUTH AFRICA: 2005-2015 [PDF]

Journal Article, Hypertension in Africa Research Team (HART), North-West University, Potchefstroom CampusPurpose: Hypertension, obesity, hyperlipidemia, and type 2 diabetes contribute primarily to noncommunicable disease deaths and together with human ...
Lammertyn, Leandi, Fourie, Carla M. T., Klipstein-Grobusch, Kerstin, Kruger, Iolanthe M, Kruger, Herculina S   +4 more
core   +1 more source

Low SLC8A1 in Colorectal Cancer Dictates Radiotherapy Resistance Through Calcium‐Dependent ANXA2+sEVs Driving M2 Polarization of TAMs

Advanced Science, EarlyView.
SLC8A1 deficiency in colorectal cancer cells increases intracellular calcium signaling, promoting the secretion of ANXA2‐enriched small extracellular vesicles. These vesicles reprogram tumor‐associated macrophages towards an M2 phenotype, which in turn fosters a tumor microenvironment conducive to radioresistance and is associated with poor patient ...
Yimin Fang, Jinghan Zhu, Qian Xiao, Qichun Wei, Xiujing He, Ping Li, Kai Jiang, Yue Liu, Yeting Hu, Weiwei Yu, Chuansheng Guo, Sheng Chen, Jian Zhao, Siqi Dai, Jingsun Wei, Hang Yang, Tongtong Bu, Kefeng Ding, Haiyan Chen   +18 more
wiley   +1 more source

Analysis of Chinese adult residents receiving healthy lifestyle advice from medical institutions

Zhongguo gonggong weisheng
ObjectiveTo understand the status of Chinese adult residents receiving healthy lifestyle advice from medical institutions and to provide evidence for promoting healthy lifestyles in China. MethodsData were collected from 170 208 residents aged ≥ 18 years
Huiyan SUN, Limin WANG, Chun LI, Xiao ZHANG, Zhenping ZHAO, Mei ZHANG   +5 more
doaj   +1 more source

Factors associated with noncommunicable disease in Mecha district, Ethiopia, 2017.

, 2019
Factors associated with noncommunicable disease in Mecha district, Ethiopia, 2017.
Yeshalem Mulugeta Demilew (3704920), Belet Sewasew Firew (6751505)   +1 more
core   +1 more source

KLF5 Downregulation Links Impaired BNIP3‐Mediated Mitophagy to Inflammatory Valve Remodeling in Calcific Aortic Valve Disease

Advanced Science, EarlyView.
In human CAVD, KLF5 is reduced in VIC‐rich regions and remodeling/stress‐associated VIC states. In VICs, KLF5 sustains BNIP3 promoter activity and BNIP3‐mediated mitophagy, thereby limiting cytosolic mtDNA accumulation. KLF5 loss weakens mitochondrial quality control and enhances mtDNA‐sensitive STING/NF‐κB/NLRP3 inflammatory signaling under osteogenic
Jin‐Hui Bian, Jia‐Xi Gu, Zhang Yue, Chun‐Ze Yuan, Hai‐Bin Ji, Ao Li, Yu Zhong, Xiu‐Fan Xu, Yu‐Qiu He, Ye‐Fan Jiang, Hong‐Shan Chen, Xiang Chen, Meng‐Lin Chao, Yong‐Feng Shao   +13 more
wiley   +1 more source

Prevalence and influencing factors of individuals at high risk of cardiovascular disease in 35 – 75 years old residents in Hebei province, 2016 – 2020: a cross-sectional survey

Zhongguo gonggong weisheng
ObjectiveTo detect individuals at high risk of cardiovascular disease (CVD) and to explore influencing factors of the risk among 35 – 75-year-old residents in Hebei province for prevention and treatment of CVD in the population.
Yuhuan LIU, Jingjing ZHAO, Fujuan YUE, Lijuan TANG, Fan ZHANG, Xiaoli LIU, Dongsheng JIANG   +6 more
doaj   +1 more source

Fiscal austerity measures hamper noncommunicable disease control goals in Brazil.

Ciência & Saúde Coletiva, 2018
Given the Constitutional Amendment 95 and the economic crisis, we discussed the possible effects of austerity measures on the achievement of the goals established for the control of chronic noncommunicable diseases (NCDs) in the country.
D. Malta, B. Duncan, M. B. de Azevedo Barros, S. Katikireddi, Fátima Marinho de Souza, A. G. da Silva, D. Machado, M. Barreto   +7 more
semanticscholar   +1 more source

Expanding Genetic Code to Generate Human Brain Organoids with Both Vasculature and Microglia‐Like Cells

Advanced Science, EarlyView.
Using genetic code expansion, we engineered vascularized human cerebral organoids (vhCOs) with microglia‐like cells and blood‐brain barrier features. vhCOs recapitulate neurovascular interactions, regional identities, and neuronal subtypes resembling the fetal brain.
Haishuang Lin, Yaqing Wang, Hu Du, Yuxin Qin, Haoyu Zhang, Peng Wang, Lin Wei, Jianhua Qin   +7 more
wiley   +1 more source

Comorbid depression and obesity: Correlates and synergistic association with noncommunicable diseases among australian men [PDF]

, 2020
INTRODUCTION: Obesity and depression are among the leading causes of disease worldwide. Their bidirectional relationship often results in comorbid depression and obesity, which further increases the risk of adverse health outcomes.
Haregu, TN, Oldenburg, B, Armstrong, G, Lee, JT   +3 more
core   +1 more source

The GPX3‐VCAM1 Axis Gates Pro‐Fibrotic Tubule Cell Fate in Hyperuricemic Nephropathy

Advanced Science, EarlyView.
Hyperuricemia induces NLRP3 inflammasome signaling activation and downregulation of GPX3 in proximal tubular epithelial cells, leading to oxidative stress–driven VCAM1 upregulation, emergence of pro‐fibrotic proximal tubule cells, macrophage recruitment, and renal fibrosis.
Yunfei Qi, Qiang Zhao, Yue Lve, Yaming Yuan, Tingting Zhou, Yue Yuan, Dexi Wu, Yifan Tang, Yan Liu, Zhigang Li, Chunping Jiang, Qiurong Ding   +11 more
wiley   +1 more source