Results 131 to 140 of about 15,499,840 (341)

Risk factors associated in multivariate analysis with perceived worsening of noncommunicable disease.

, 2020
Risk factors associated in multivariate analysis with perceived worsening of noncommunicable disease.
Blanche Greene-Cramer (7405772), Oleg Bilukha (3483986), Alexia Couture (8741442), Barbara Lopes-Cardozo (8741436), Farah Husain (8741439), Aimee Summers (382838)   +5 more
core   +1 more source

The potential impact of pre-exposure prophylaxis for HIV prevention among men who have sex with men and transwomen in Lima, Peru: a mathematical modelling study. [PDF]

, 2012
BACKGROUND: HIV pre-exposure prophylaxis (PrEP), the use of antiretroviral drugs by uninfected individuals to prevent HIV infection, has demonstrated effectiveness in preventing acquisition in a high-risk population of men who have sex with men (MSM ...
Robert M Grant, Grant, RM, Gomez, Gabriela B, Robert M. Grant (128215), Hallett, Timothy B., Gabriela B. Gomez (128197), Hallett, TB, Segura, Eddy R., Grant, Robert M., Grant, Robert, Garnett, Geoff P, Geoff P Garnett, Caceres, CF, Gomez, Gabriela B., Caceres, Carlos F., Timothy B. Hallett (89580), Hallett, Timothy B, Carlos F. Caceres (128205), Borquez, Annick, Gomez, GB, Borquez, A, Grant, Robert M, Segura, ER, Gabriela B Gomez, Annick Borquez (128201), Annick Borquez, Geoff P. Garnett (92067), Segura, Eddy R, Carlos F Caceres, Eddy R Segura, Caceres, Carlos F, Timothy B Hallett, Garnett, Geoff P., Garnett, GP, Eddy R. Segura (128211)   +34 more
core   +2 more sources

A Hepatocyte‐to‐Stellate Cell Axis Couples Alternate‐Day Fasting to Liver Fibrosis Resolution via ATG7 S‐Nitrosylation

Advanced Science, EarlyView.
Alternate‐day fasting suppresses mitochondrial complex II assembly via SDHAF4 to upregulate hepatocyte eNOS. The resulting nitric oxide S‐nitrosylates ATG7 at C184 in hepatic stellate cells, restraining autophagic flux and preventing their profibrotic activation.
Xueqiang Wang, Mengqi Zeng, Cunxiao Sun, Yuhan Gou, Zhaode Feng, Weiqiang Lv, Chaoying Yan, Hansen Wu, Pengfei Zhang, Jie Xu, Ke Cao, Hao Li, Mingge Ding, Zhongbo Liu, Xing Zhang, Jiankang Liu, Xuan Zou, Zhihui Feng   +17 more
wiley   +1 more source

Reproductive health and rheumatoid arthritis

BMC Rheumatology
Introduction The prevalence of Rheumatoid Arthritis (RA) has been steadily increasing over the last thirty years, particularly among women. Due to the conflicting results of various studies on the link between rheumatoid arthritis and reproductive health,
Mohammad Erfan Ranjbaran, Maryam Kazemi
doaj   +1 more source

Correlation between noncommunicable disease mortality in people aged 30-69 years and those aged 70-89 years

, 2019
Objective: To investigate whether the key metric for monitoring progress towards sustainable development goal target 3.4 that is measuring premature noncommunicable disease mortality (deaths among people aged 30-69 years), is ageist.Methods: To examine ...
Byass, Peter,
core   +1 more source

NS1‐Induced PARP1 Phase Transitions Prolongs Host Transcriptional Pausing to Promote Influenza A Virus Replication

Advanced Science, EarlyView.
After IAV infection, NS1 induces PARP1 phase transition, reducing molecular mobility in condensates, prolonging host transcriptional pause, aiding RdRp cap snatching, and promoting viral transcription. ABSTRACT Influenza A virus (IAV) commandeers host transcriptional machinery to replicate, but mechanisms remain elusive.
Shufeng Ma, Changyuan Kang, Xixian Liu, Lichao Yang, Mengyi Li, Yuting Ye, Jianfang Zhang, Yingjun Li, Guanghui Jin, Yang Liu, Xiaohong Chen, Kexin Wang, Zifeng Yang   +12 more
wiley   +1 more source

A Multi‐Targeting Chimeric Antigen Receptor‐T Cell Platform to Overcome Antigen Heterogeneity in the Treatment of Non‐Small Cell Lung Cancer

Advanced Science, EarlyView.
A dual‐transmembrane Bicephali CAR‐T platform simultaneously targets CD276 and NKG2D ligands to address antigen heterogeneity in non‐small cell lung cancer. By improving immune synapse formation, mitochondrial fitness, antioxidant capacity, and stem‐like persistence, this design enhances durable tumor control and provides a versatile strategy to ...
Lina Wang, Yanlei Zhang, Shuixiu Peng, Chenchen Hou, Huaqi Guo, Tianyu Zhou, Alex H. Chang, Lifeng Yan, Weining Xiong   +8 more
wiley   +1 more source

Cancer Burden and Control in the Western Pacific Region: Challenges and Opportunities

Annals of Global Health, 2014
Background: Cancer has become a priority public health challenge in the Member States of the World Health Organization’s (WHO) Western Pacific Region (WPR).
Cherian Varghese, Marie Clem Carlos, Hai-Rim Shin   +2 more
doaj   +1 more source

Noncommunicable disease-attributable medical expenditures, household financial stress and impoverishment in Bangladesh

SSM: Population Health, 2018
Background Treatment of noncommunicable diseases (NCDs) in low-income countries can entail large out-of-pocket (OOP) medical expenditures, which can increase the likelihood of household impoverishment and perpetuate the poverty cycle.
B. Datta, M. Husain, M. Husain, D. Kostova   +3 more
semanticscholar   +1 more source

Transformer‐Based Multitask Framework Integrating Habitat and Deep Learning for Predicting Early Disease Control and Survival in Immunotherapy‐Treated Hepatocellular Carcinoma

Advanced Science, EarlyView.
This study developed ECOS‐Net, a transformer‐based multitask framework integrating CT‐derived habitat and 2.5D deep learning features to simultaneously predict early disease control and overall survival in hepatocellular carcinoma patients treated with immune checkpoint inhibitors.
Xiaona Fu, Yusheng Guo, Bingxin Gong, Jie Lou, Ning Wang, Xuejun Chen, Hongtao Hu, Rundong Wang, Xiaofang Guo, Shanmei Li, Yangyang Xie, Shichao Long, Mengsi Li, Shubo Pan, Wen Shen, Zhaogang Zhang, Zifang Song, Pengchen Liang, Xiaoyun Liang, Peng Sun, Guilin Zhang, Shanshan Jiang, Jinxiang Zhang, Lian Yang   +23 more
wiley   +1 more source