Results 121 to 130 of about 15,499,840 (341)

Diabetic kidney disease screening status and related factors: a cross-sectional study of patients with type 2 diabetes in six provinces in China

BMC Health Services Research
Objective To understand the awareness and practice of diabetic kidney disease (DKD) or nephropathy screening among community-based patients with type 2 diabetes in six provinces and cities in China, and to analyse the related factors affecting screening ...
Zhang Xia, Xuechun Luo, Yanzhi Wang, Tingling Xu, Jianqun Dong, Wei Jiang, Yingying Jiang   +6 more
doaj   +1 more source

Fecal hemoglobin concentration as a risk stratification tool for advanced colorectal neoplasm in a community-based screening program

Frontiers in Oncology
BackgroundCompared with traditional binary classification, the quantitative fecal immunochemical test (qFIT) provides detailed fecal hemoglobin (f-Hb) concentrations, which facilitate more refined risk stratification for advanced colorectal neoplasm ...
Xiaocong Zhang, Kai Gu, Yangming Gong, Chunxiao Wu, Yi Pang, Mengyin Wu, Yan Shi   +6 more
doaj   +1 more source

Towards a Compositional Framework for Describing Human Phenotypes

Advanced Science, EarlyView.
The Phenotype Assembly Method (PhenoAM) decomposes phenotype variables into measurable Features and typed Qualifiers, enabling standardized, machine‐readable Phenome Data Elements (PhenoDEs) that preserve measurement context. Applied in the International Human Phenome Project (IHPP), the framework yields 58 371 PhenoDEs and supports component‐level ...
Wanting Hu, Yunchao Ling, Xinyue Hu, Wei Chen, Rong Zhou, Xinhao Zhuang, Yanfeng Jiang, Jialu Zhao, Xingdong Chen, Jingchun Luo, Li Jin, Guoqing Zhang   +11 more
wiley   +1 more source

Created Ex Nihilo: A Near‐Infrared Afterglow Luminescent Framework of Imidazole Derivatives for Bioimaging

Angewandte Chemie, EarlyView.
A series of Ir(III) complexes (Ir‐1‐Ir‐4) based on imidazole derivatives provide a new afterglow luminescence mechanism. The work expands the range of afterglow luminescence frameworks to overcome: (i) a lack of new afterglow scaffolds; (ii) the dependence on initial external light activation; and (iii) aggregation‐caused quenching.
Zihan Wu, Liping Zhang, Ziwei Wang, Yachao Wang, Gelin Xu, Feng Chi, Dongxia Zhu, Martin R. Bryce, Ben Zhong Tang, Lijie Ren   +9 more
wiley   +2 more sources

Citywide community-based colorectal cancer screening in urban Shanghai: age and sex variations in risk mitigation from 1973 to 2020

Frontiers in Oncology
AimsTo evaluate the impact of Shanghai’s community colorectal cancer (CRC) screening program on CRC epidemiology and risk reduction.Materials and methodsData from the Shanghai Cancer Registry (1973-2020) were analyzed.
Mengyin Wu, Yangming Gong, Chunxiao Wu, Peng Peng, Lei Chen, Qi Li, Liang Shi, Yongmei Xiang, Jianming Dou, Yi Pang, Xiaocong Zhang, Kai Gu, Yan Shi   +12 more
doaj   +1 more source

Noncommunicable disease prevalence among conflict-affected adults in Ukraine, by sex and age.

, 2020
Noncommunicable disease prevalence among conflict-affected adults in Ukraine, by sex and age.
Blanche Greene-Cramer (7405772), Oleg Bilukha (3483986), Alexia Couture (8741442), Barbara Lopes-Cardozo (8741436), Farah Husain (8741439), Aimee Summers (382838)   +5 more
core   +1 more source

An Extracellular Pore‑Targeting Peptide Defines a Designable Allosteric Site in TRPV2

Advanced Science, EarlyView.
Structure‐guided peptide engineering yields Depiv2, a highly potent and subtype‐selective TRPV2 inhibitor that binds to the extracellular pore and remodels it into a closed, non‐conductive state. Depiv2 suppresses pathological cardiac hypertrophy, establishing the TRPV2 outer pore as a designable interface for selective peptide modulation.
Aiqin Zhu, Hongkun Wang, Jiawei Wang, Xiaolu Liu, Aerziguli Aierken, Lizhen Xu, Ping Liang, Fan Yang   +7 more
wiley   +1 more source

Prevalence and influencing factors of regular physical activity among community-dwelling adults in Shaanxi province, 2018: an analysis of surveillance data

Zhongguo gonggong weisheng
ObjectiveTo investigate the prevalence of regular physical activity and its influencing factors among adult community residents in Shaanxi province, providing a reference for behavioral interventions targeting the general population, especially key ...
Yali TAO, Rina SA, Weihua WANG, Meng WU, Rong LIU, Lin QIU   +5 more
doaj   +1 more source

Relation between the Global Burden of Disease and Randomized Clinical Trials Conducted in Latin America Published in the Five Leading Medical Journals [PDF]

, 2008
Background: Since 1990 non communicable diseases and injuries account for the majority of death and disability-adjusted life years in Latin America. We analyzed the relationship between the global burden of disease and Randomized Clinical Trials (RCTs ...
Ortiz, Z, Perel, P, Ortiz, Zulma, Juan Pablo Casas, Miranda, JJ, Casas, JP, Miranda, J Jaime, Casas, Juan Pablo, Pablo Perel, J Jaime Miranda, Zulma Ortiz, Perel, Pablo   +11 more
core   +1 more source

Isocyanate‐Modified Melatplatin(IV) Enhances Antitumor Efficacy via TCF4/COL6A3‐Mediated Extracellular Matrix Remodeling and cGAS‐STING Pathway Activation in Bladder Cancer

Advanced Science, EarlyView.
A series of melatonin‐conjugated platinum(IV) prodrugs was functionalized with isocyanate chains (compounds 5‒12). MP‐12C (compound 11) was identified as the lead candidate, with optimal potency and safety. MP‐12C exhibited greater efficacy than cisplatin by increasing intracellular uptake, reshaping the extracellular matrix, activating the cGAS‐STING ...
Linhui Wang, Xiaomeng Liu, Tao Zhu, Zirun Su, Ruiping Liu, Zhe Li, Kaixuan Du, Kaipeng Jia, Chong Fu, Yuda Lin, Zihan Xue, Zhe Zhang, Chong Shen, Yunkai Qie, Zhouliang Wu, Zhiheng Liu, Kangkang Liu, Jingyuan Xu, Hailong Hu   +18 more
wiley   +1 more source