Results 41 to 50 of about 2,172,307 (300)

A cohort study protocol to analyze the predisposing factors to common chronic non-communicable diseases in rural areas: Fasa Cohort Study

BMC Public Health, 2016
Background Non-communicable diseases (NCDs) have become the main causes of morbidity and mortality even in rural areas of many developing countries, including Iran.
Mojtaba Farjam, Hossein Bahrami, Ehsan Bahramali, Javad Jamshidi, Alireza Askari, Habibollah Zakeri, Reza Homayounfar, Hossein Poustchi, Reza Malekzadeh   +8 more
doaj   +1 more source

Dietary Fats and Chronic Noncommunicable Diseases [PDF]

Nutrients, 2018
The role of dietary fat has been long studied as a modifiable variable in the prevention and treatment of noncommunicable cardiometabolic disease. Once heavily promoted to the public, the low-fat diet has been demonstrated to be non-effective in preventing cardiometabolic disease, and an increasing body of literature has focused on the effects of a ...
Hayley E. Billingsley, Salvatore Carbone, Carl J. Lavie   +2 more
openaire   +5 more sources

Thymosin Alpha‐1 Provides Direct Neuroprotection by Engaging the Orexin Receptor HCRTR1 to Suppress Neuronal Necroptosis

Advanced Science, EarlyView.
In this study, we unveil a thymus‐brain endocrine axis wherein Tα1 engages HCRTR1 to inhibit RIPK3‐mediated necroptosis. This study nominates the Tal‐HCRTR1‐RIPK3 axis as a potent and clinically translatable therapeutic target for stroke and neurodegeneration.
Xinmei Kang, Shisi Wang, Liubin Zhang, Mengyan Hu, Xiaotao Su, Yuxin Liu, Qin Qin, Haotong Yi, Liling Yuan, Wei Cai, Lei Wei, Zhengqi Lu   +11 more
wiley   +1 more source

Tuberculosis comorbidity with communicable and non-communicable diseases: integrating health services and control efforts. [PDF]

, 2013
Recent data for the global burden of disease reflect major demographic and lifestyle changes, leading to a rise in non-communicable diseases. Most countries with high levels of tuberculosis face a large comorbidity burden from both non-communicable and ...
Abubakar, Ibrahim, Pletschette, Michel, Migliori, Giovanni Battistai, Migliori, Giovanni Battista, Zafar, Afia, Hoelscher, Michael, Pantaleo, Guiseppe, Kim, Peter, Lawn, Stephen D, Swaminathan, Soumya, Memish, Ziad A, Maeurer, Markus, Hasan, Rumina, Marais, Ben J., A Memish, Ziad, Marais, Ben J, Zumla, Alimuddin, Craig, Gill, Lawn, Stephen D., Glaziou, Philippe, Lönnroth, Knut, Mwaba, Peter, Schito, Marco, Zijenah, Lynn, Bates, Matthew, Memish, Ziad A., Colagiuri, Ruth, Mwaba, P., Zafar, A., Hasan, R., Zijenah, L., Marais, B.J., Glaziou, P., Kim, P., Abubakar, I., Pletschette, M., Lönnroth, K., Migliori, G.B., Hoelscher, M., Memish, Z.A., Bates, M., Craig, G., Lawn, S.D., Colagiuri, R., Pantaleo, G., Zumla, A., Schito, M., Maeurer, M., Swaminathan, S.   +48 more
core   +1 more source

UDP‐Glucose‐6‐Dehydrogenase Mediated O‐GlcNAcylation of Tight Junction Protein 1 Suppresses Metastasis in Renal Cell Carcinoma

Advanced Science, EarlyView.
Our research unveiled a regulatory paradigm wherein TRIM25 orchestrates the ubiquitin‐mediated degradation of UGDH. UGDH modulates the protein stability of TJP1 by regulating O‐GlcNAcylation levels, effectively impeding the metastasis of ccRCC. Our insights elevate UGDH to a pivotal biomarker and tumor suppressor, marking the first demonstration that ...
Xiaolin Chen, Yuhang Bao, Tao Liu, Jianhui Qiu, Yuanyuan Ma, Zedan Zhang, Chuandong Wang, Ruiyi Deng, Zheng Song, Tianyi He, Haode Liu, Jingcheng Zhou, Yizhou Wang, Kan Gong   +13 more
wiley   +1 more source

Targeted Temperature Management in Pregnant Patients after Cardiac Arrest: A Systematic Review [PDF]

Iranian Journal of Medical Sciences
Background: Targeted temperature management (TTM) is a standard care intervention following resuscitation, known to improve neurological outcomes in patients.
Sina Azadikhah Jahromi, Mina Ostovan, Razieh Zahedi, Zhila Rahmanian, Pegah Abdollahzadeh   +4 more
doaj   +1 more source

Perception and practice of ‘healthy’ diet in relation to noncommunicable diseases among the urban and rural people in northern Ethiopia: a community-based qualitative study [PDF]

, 2018
2018-11Dietary habits are related to the risks of noncommunicable diseases (NCDs), such as cardiovascular disease and diabetes, of which burdens are increasing in low-income countries including Ethiopia.
Hirakawa, Yoshihisa, Matsuyama, Akiko, Lemlem Weldegerima Gebremariam, Chiang, Chifa, Aoyama, Atsuko, Alemayehu Bayray Kahsay, Yatsuya, Hiroshi   +6 more
core   +1 more source

scTIDE: Deciphering Critical Transitions Through Cell‐Perturbed Manifold Graphs and Optimal Transport Conditional Flow Matching

Advanced Science, EarlyView.
scTIDE identifies single‐cell tipping points by combining manifold‐based graph representations with optimal‐transport conditional flow matching, which preserves intrinsic topology and models distributional dynamics. It supports critical‐transition detection at individual‐cell resolution, prediction of unseen cells, and dimensionality reduction and ...
Jiayuan Zhong, Bowen Niu, Yongbo Yu, Shiyang Nie, Xuerong Gu, Pei Chen, Rui Liu   +6 more
wiley   +1 more source

Protocol for the development of the WHO package of ear and hearing care interventions

BMJ Public Health
Introduction This protocol article describes the methodology that guides the development of the package of ear and hearing care interventions (PEHCI), led by the WHO.
Shelly Chadha, Carolina Der, Pallavi Mishra, Lauren K Dillard   +3 more
doaj   +1 more source

Demographic and environmental factors associated with disability in India, Laos, and Tajikistan: a population-based cross-sectional study

BMC Public Health, 2022
Background The number of people experiencing functional limitations due to health conditions (capacity) is expected to increase in low and middle-income countries as populations age and rates of non-communicable disease rise.
Michael Zhu Chen, Lindsay Lee, Carolina Fellinghauer, Alarcos Cieza, Somnath Chatterji   +4 more
doaj   +1 more source