Results 51 to 60 of about 2,707,119 (197)

Outcomes of pregnancies with trisomy 16 mosaicism detected by NIPT: a series of case reports

Molecular Cytogenetics, 2021
Background Trisomy 16 (T16) is thought to be the most frequent chromosome abnormality at conception, which is often associated with a high risk of abnormal outcomes.
Haishan Peng, Jiexia Yang, Dongmei Wang, Fangfang Guo, Yaping Hou, Aihua Yin   +5 more
doaj   +1 more source

Noninvasive Prenatal Testing in Modern Day Pregnancy Care. [PDF]

, 2022
BACKGROUND Literature review of noninvasive prenatal testing in modern-day pregnancy care for collecting information about methods, limitations and benefits of this technique.
Momeni, Kiana Marie,
core  

Noninvasive prenatal testing of α-thalassemia and β-thalassemia through population-based parental haplotyping

Genome Medicine, 2021
Background Noninvasive prenatal testing (NIPT) of recessive monogenic diseases depends heavily on knowing the correct parental haplotypes. However, the currently used family-based haplotyping method requires pedigrees, and molecular haplotyping is highly
Chao Chen, Ru Li, Jun Sun, Yaping Zhu, Lu Jiang, Jian Li, Fang Fu, Junhui Wan, Fengyu Guo, Xiaoying An, Yaoshen Wang, Linlin Fan, Yan Sun, Xiaosen Guo, Sumin Zhao, Wanyang Wang, Fanwei Zeng, Yun Yang, Peixiang Ni, Yi Ding, Bixia Xiang, Zhiyu Peng, Can Liao   +22 more
doaj   +1 more source

What are women saying about noninvasive prenatal testing? An analysis of online pregnancy discussion forums

, 2019
OBJECTIVE:The aim of this study was to explore what women are saying about noninvasive prenatal testing (NIPT) in online discussion forums. METHODS:Inductive thematic analysis of content from 13 open-access discussion forums written in English from 11 ...
Rebecca E.S. Crabbe, Peter Stone, Filoche, Sara K, Crabbe, Rebecca ES, Stone, Peter, Sara K. Filoche   +5 more
core   +1 more source

Clinical experience of noninvasive prenatal testing for rare chromosome abnormalities in singleton pregnancies

Frontiers in Genetics, 2022
Objectives: The study aimed to investigate the clinical use of noninvasive prenatal testing (NIPT) for common fetal aneuploidies as a prenatal screening tool for the detection of rare chromosomal abnormalities (RCAs).Methods: Gravidas with positive NIPT ...
Ting Hu, Ting Hu, Ting Hu, Jiamin Wang, Jiamin Wang, Jiamin Wang, Qian Zhu, Qian Zhu, Qian Zhu, Zhu Zhang, Zhu Zhang, Zhu Zhang, Rui Hu, Rui Hu, Rui Hu, Like Xiao, Like Xiao, Like Xiao, Yunyuan Yang, Yunyuan Yang, Yunyuan Yang, Na Liao, Na Liao, Na Liao, Sha Liu, Sha Liu, Sha Liu, He Wang, He Wang, He Wang, Xiaoyu Niu, Xiaoyu Niu, Shanling Liu, Shanling Liu, Shanling Liu   +34 more
doaj   +1 more source

Hemolytic Disease of the Fetus and Newborn: Fetal RHD Genotyping, Targeted Prophylaxis, and Prenatal Therapies

Prenatal Diagnosis, EarlyView.
ABSTRACT Hemolytic disease of the fetus and newborn (HDFN) remains a significant concern in prenatal care primarily caused by maternal alloimmunization against fetal red blood cell antigens, most commonly the D antigen. Noninvasive fetal RHD genotyping, used as a screening tool, enables targeted antenatal prophylaxis and has been implemented in several
Emilie Thorup, Steffen Thorsen, Morten Hanefeld Dziegiel, Olav Bjørn Petersen, Frederik Banch Clausen   +4 more
wiley   +1 more source

Clinical Utility of Nuchal Translucency Measurement in First‐Trimester Ultrasound Screening in a Setting With First‐Tier NIPT for Aneuploidy Screening

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective To investigate the additional clinical value of nuchal translucency (NT) measurement at the first‐trimester anomaly scan (FTAS) in a setting with first‐tier non‐invasive prenatal testing (NIPT). Method This nationwide prospective cohort study, part of the IMITAS study on FTAS implementation, included all pregnancies with increased NT
Eline E. R. Lust, Kim Bronsgeest, Lidewij Henneman, Neeltje M. T. H. Crombag, Caterina M. Bilardo, Robert‐Jan H. Galjaard, Esther Sikkel, Audrey B. C. Coumans, Ayten Elvan‐Taşpınar, Sander Galjaard, Attie T. J. I. Go, Gwendolyn T. R. Manten, Eva Pajkrt, Elisabeth van Leeuwen, Monique C. Haak, Mireille N. Bekker   +15 more
wiley   +1 more source

Fetal Brain Abnormalities in Trisomy 21 and Associated Neurodevelopmental Outcome: Key Factors to Identify Differences in Neurodevelopmental Outcome?

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective Trisomy 21 (T21) is associated with various neurological impairments. However, the mechanisms of fetal brain development in T21 and their impact on neurodevelopmental outcomes remain unclear, limiting prenatal counseling. Therefore, this study aims to assess neuropathological changes in fetuses with T21 and the associated ...
Christina Haberl, Pilar Palmrich, Eva Karner, Patric Kienast, Sarah Glatter, Florian Heinzl, Philipp Moser, Daniela Prayer, Gregor Kasprian, Julia Binder   +9 more
wiley   +1 more source

P3-67 Patient and professional experiences with non-invasive prenatal diagnosis (NIPD) and testing (NIPT): social and ethical issues raised

, 2015
Objectives: The aim of this study is to gain a rich understanding of early experiences with emerging non-invasive prenatal diagnosis (NIPD) and non-invasive prenatal testing (NIPT) testing technologies.
Strange, Heather
core   +1 more source

Coexistence of Suspected Tetralogy of Fallot With Absent Pulmonary Valve and Dextrocardia in Pre‐Gestational Diabetes Mellitus: A Case Report

Clinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT Early fetal echocardiography and serial surveillance are crucial in pregnancies complicated by pregestational diabetes. Tetralogy of Fallot with absent pulmonary valve syndrome may cause progressive cardiomegaly, ventricular hypertrophy, hydrops, and fetal demise.
Alireza Golbabaei, Vida Kahani, Marzieh Mousivand   +2 more
wiley   +1 more source