Results 41 to 50 of about 277,674 (289)

Quantized‐feedback hands‐off control for nonlinear systems

IET Control Theory & Applications, 2021
This paper addresses a quantized feedback hands‐off control for a class of nonlinear systems. Here, [K,KL] sector is constructed with the suitable choice of control‐Lyapunov function.
Ankit Sachan, Xiaogang Xiong, Sandeep Kumar Soni, Shyam Kamal, Sandip Ghosh   +4 more
doaj   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Threshold adjustment of deviations from the law of one price [PDF]

Using self-exciting threshold autoregressive models, we explore the validity of the law of one price (LOOP) for sixteen sectors in nine European countries.
Juvenal, Luciana, Taylor, Mark P.
core   +1 more source

Nonlinear Atmospheric Adjustment to Thermal Forcing

Journal of the Atmospheric Sciences, 2005
Abstract A nonlinear, numerical model of a compressible atmosphere is used to simulate the hydrostatic and geostrophic adjustment to a localized prescribed heating applied over five minutes with a size characteristic of an isolated, deep, cumulus cloud.
Peter R. Bannon, Paul F. Fanelli
openaire   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Shape Adjustment of a Large Planar Phased Array Antenna With Nonlinear Cable Actuators

International Journal of Aerospace Engineering
Shape adjustment of large planar phased array antennas is significant because the shape distortion of phased arrays can greatly reduce the antenna’s gain in the observing direction.
Jiyang Zhou, Xiang Liu, Guoping Cai, Jun Sun, Dongfang Zhu   +4 more
doaj   +1 more source

Data Quality Assessment of Time-Variable Surface Microgravity Surveys in the Southeastern Tibetan Plateau

Applied Sciences, 2022
Ground-based time-variable gravimetry with high accuracy is an important approach in monitoring geodynamic processes. The uncertainty of instruments including scale factor (SF) and drift rate are the primary factors affect the quality of observation data.
Qiuyue Zheng, Xiuyi Yao, Shi Chen, Jinling Yang, Dong Liu, Zhengyu Chen   +5 more
doaj   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

DESIGN AND EXPERIMENTAL ANALYSIS OF A NONLINEAR ULTRAHARMONIC VIBRATOR EXCITER

Jixie qiangdu, 2022
Aiming at the problem that the vibration frequency of conventional vibration exciter is small and can not realize the resonance of high stiffness components, Based on the superharmonic vibration characteristics of nonlinear vibration system, designed a ...
WANG ChengJun, SHANG ChenChen, ZHANG YuPing   +2 more
doaj  

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source