Results 51 to 60 of about 396,352 (242)

A Study of Nonlinear Fractional-Order Boundary Value Problem with Nonlocal Erdelyi-Kober and Generalized Riemann-Liouville Type Integral Boundary Conditions

Mathematical Modelling and Analysis, 2017
We investigate a new kind of nonlocal boundary value problems of nonlinear Caputo fractional differential equations supplemented with integral boundary conditions involving Erdelyi-Kober and generalized Riemann-Liouville fractional integrals.
Bashir Ahmad, Sotiris K. Ntouyas, Jessada Tariboon, Ahmed Alsaedi   +3 more
doaj   +1 more source

Investigation of hybrid fractional q-integro-difference equations supplemented with nonlocal q-integral boundary conditions

Demonstratio Mathematica, 2023
In this article, we introduce and study a new class of hybrid fractional qq-integro-difference equations involving Riemann-Liouville qq-derivatives, supplemented with nonlocal boundary conditions containing Riemann-Liouville qq-integrals of different ...
Alsaedi Ahmed, Ahmad Bashir, Al-Hutami Hana, Alharbi Boshra   +3 more
doaj   +1 more source

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky, Cara Joyce, H. Jeremy Bockholt, Paul A. Rudnick, William H. Adams, Fiona McAllister, Justin W. Smock, Michael A. Newton, Jane S. Paulsen   +8 more
wiley   +1 more source

Unraveling the Molecular Mechanisms of Glioma Recurrence: A Study Integrating Single‐Cell and Spatial Transcriptomics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Glioma recurrence severely impacts patient prognosis, with current treatments showing limited efficacy. Traditional methods struggle to analyze recurrence mechanisms due to challenges in assessing tumor heterogeneity, spatial dynamics, and gene networks.
Lei Qiu, Yinjiao Fei, Jiaxuan Ding, Kexin Shi, Jinyan Luo, Yuchen Zhu, Xingjian Sun, Gefei Jiang, Yuandong Cao, Weilin Xu, Shu Zhou   +10 more
wiley   +1 more source

The superposition operator in the space of functions continuous and converging at infinity on the real half-axis

Advances in Nonlinear Analysis, 2019
We will consider the so-called superposition operator in the space CC(ℝ+) of real functions defined, continuous on the real half-axis ℝ+ and converging to finite limits at infinity.
Rzepka Beata, Ścibisz Justyna
doaj   +1 more source

Association of CDKN2A/B Homozygous Deletion and Extent of Resection With Survival of Patients With WHO CNS5 Grade 4 Astrocytoma

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives WHO grade 4 astrocytomas are associated with poor prognosis, and their prognostic factors remain controversial. This study aimed to identify the prognostic factors and develop a management algorithm for these patients. Methods This study retrospectively included 151 CNS5 adult grade 4 astrocytomas from two medical centers.
Jiawei Cai, Guanglin Zhu, Qiu He, Chen Luo, Lingyun Zhuo, Xingfu Wang, Yiming Chen, Xiaoyong Chen, Wendong You, Jiaheng Xu, Yuanxiang Lin, Dezhi Kang, Shuai Wu, Zanyi Wu   +13 more
wiley   +1 more source

The influence of thermal and conductive temperatures in a nanoscale resonator

Results in Physics, 2018
In this work, the thermoelastic interaction in a nano-scale resonator based on two-temperature Green-Naghdi model is established. The nanoscale resonator ends were simply supported.
Aatef Hobiny, Ibrahim A. Abbas
doaj   +1 more source

Brainstem and Cerebellar Volume Loss and Associated Clinical Features in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Progressive Supranuclear Palsy (PSP) is a neurodegenerative ‘tauopathy’ with predominating pathology in the basal ganglia and midbrain. Caudal tau spread frequently implicates the cerebellum; however, the pattern of atrophy remains equivocal.
Chloe Spiegel, Timothy P. Siejka, Cassandra Marotta, Josh J. Y. Lee, Kelly Bertram, Terence J. O'Brien, Meng Law, Lucy Vivash, Ian H. Harding   +8 more
wiley   +1 more source

Oscillation and nonoscillation theorems of neutral dynamic equations on time scales

Advances in Difference Equations, 2019
We present the oscillation criteria for the following neutral dynamic equation on time scales: (y(t)−C(t)y(t−ζ))Δ+P(t)y(t−η)−Q(t)y(t−δ)=0,t∈T, $$ \bigl(y(t)-C(t)y(t-\zeta )\bigr)^{\Delta }+P(t)y(t-\eta )-Q(t)y(t-\delta )=0, \quad t\in {\mathbb{T ...
Yong Zhou, Ahmed Alsaedi, Bashir Ahmad
doaj   +1 more source

Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher, Charles B. Malpas, Stuart J. McDonald, William T. O’Brien, Craig Despott, Kelly L. Bertram, Matthew P. Pase, Lukas Frontzkowski, Meng Law, Terence J. O’Brien, Lucy Vivash   +10 more
wiley   +1 more source