Results 41 to 50 of about 157,495 (266)
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Communications BiologyMyosin motors are fundamental biological actuators that power diverse mechanical tasks in eukaryotic cells via ATP hydrolysis. Previous work has linked myosin’s velocity-dependent detachment rate to macroscopic scale muscle dynamics described by Hill’s ...
Jake McGrath +3 more
doaj +1 more source
NONLINEAR RELAXATION IN POPULATION DYNAMICS [PDF]
Scaling and Disordered Systems, 2002 We analyze the nonlinear relaxation of a complex ecosystem composed of many interacting species. The ecological system is described by generalized Lotka-Volterra equations with a multiplicative noise. The transient dynamics is studied in the framework of the mean field theory and with random interaction between the species. We focus on the statistical
Cirone, Markus A. +2 more
openaire +3 more sources
Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley +1 more source
Fractional dynamic system simulating the growth of microbe
Advances in Difference Equations, 2021 There are different approaches that indicate the dynamic of the growth of microbe. In this research, we simulate the growth by utilizing the concept of fractional calculus.
Samir B. Hadid, Rabha W. Ibrahim
doaj +1 more source
Application and Assessment of Cooperative Localization in Three-Dimensional Vehicle Networks
Applied Sciences, 2022 The trajectory planning and control of multi-agent systems requires accurate localization, which may not be possible when GPS signals and fixed features required for SLAM are not available.
Juan Carlos Oliveros, Hashem Ashrafiuon
doaj +1 more source
Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer
Aging and Cancer, EarlyView.Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss +12 more
wiley +1 more source
Symmetry in Nonlinear Dynamics and Chaos
Symmetry, 2022 Nonlinear dynamics and chaos have collaborated to increase our understanding of several phenomena [...]
openaire +2 more sources
Predictive Value of Composite Inflammatory Markers for Stroke Prognosis: A Prospective Cohort Study
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Novel composite inflammatory markers' role in stroke prognosis is understudied, and the best predictor is unclear, requiring further exploration. Objectives This study aimed to systematically evaluate the associations of 6 novel composite inflammatory markers on stroke prognosis.
Bing Wu +7 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To evaluate the diagnostic accuracy of glial fibrillary acidic protein (GFAP) measured in dried plasma spots versus conventional plasma‐ and serum‐GFAP testing for assessment of disease severity in aquaporin‐4 immunoglobulin G–positive neuromyelitis optica spectrum disorder (AQP4‐IgG+ NMOSD).
Felix Wohlrab +19 more
wiley +1 more source